Quais Mujawar
- Pediatric Hepatobiliary Diseases and Treatments
- Liver Disease and Transplantation
- Gallbladder and Bile Duct Disorders
- Gastrointestinal disorders and treatments
- COVID-19 Clinical Research Studies
- Poisoning and overdose treatments
- Inflammasome and immune disorders
- Parasites and Host Interactions
- Sleep and related disorders
- Pancreatic function and diabetes
- Connective tissue disorders research
- Child Nutrition and Feeding Issues
- Plant and fungal interactions
- Stoma care and complications
- Pancreatitis Pathology and Treatment
- Congenital Diaphragmatic Hernia Studies
- Cardiovascular Syncope and Autonomic Disorders
- Drug Transport and Resistance Mechanisms
- Pharmacological Effects and Toxicity Studies
- Gastrointestinal Tumor Research and Treatment
- Neonatal and fetal brain pathology
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Metastasis and carcinoma case studies
- Kawasaki Disease and Coronary Complications
- Therapeutic Uses of Natural Elements
University of Manitoba
2017-2023
Health Sciences Centre
2017-2019
King Khalid University
2014
King Saud University
2011-2014
King Khalid University Hospital
2011-2014
Kokilaben Dhirubhai Ambani Hospital
2011
Al-Ameen Medical College
2009-2011
Background and Aims: Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, real‐world lacking. This study aimed to elucidate the natural history of liver disease in contemporary, international cohort children with ALGS. Approach Results: was multicenter retrospective clinically and/or genetically confirmed ALGS diagnosis, born between January 1997 August 2019. Native survival (NLS) event‐free rates...
Background and Aims: Alagille syndrome (ALGS) is characterized by chronic cholestasis with associated pruritus extrahepatic anomalies. Maralixibat, an ileal bile acid transporter inhibitor, approved pharmacologic therapy for cholestatic in ALGS. Since long-term placebo-controlled studies are not feasible or ethical children rare diseases, a novel approach was taken comparing 6-year outcomes from maralixibat trials aligned harmonized natural history cohort the G lobal AL agille A lliance...
Pycnodysostosis is a rare clinical entity, first described in 1962 by Maroteaux and Lamy. The disease has also been named Toulouse-Lautrec syndrome, after the French artist Henri de Toulouse-Lautrec, who (it surmised) suffered from disease. In 1996, defective gene responsible for was located, offering accurate diagnosis, carrier testing more thorough understanding of this disorder. It an autosomal recessive osteochondrodysplasia, usually diagnosed at early age with incidence estimated to be...
Increased mortality risk because of severe acute respiratory syndrome coronavirus-2 (SARS-CoV2) infection in adults with native liver disease (LD) and transplant (LT) is associated advanced age comorbid conditions. We aim to report outcomes for children LD LT enrolled the NASPGHAN/SPLIT SARS-CoV2 registry.
Percutaneous liver biopsy (LB) is the gold standard method for evaluation and management of patients with disease. The purpose this study was to characterize pediatric undergoing LB at British Columbia Children's Hospital, determine rate timing complications following procedure. medical records all pediat-ric who underwent during a six-year retrospective were reviewed collect demographic procedure-related data. 223 LBs performed, 179 these biopsies percutaneous or transjugular. Elevated...
To determine the effects and safety of dioctahedral smectite (DS) on duration acute watery diarrhea in children.A Randomized, open labeled, clinical controlled trial a tertiary care hospital outpatient department (OPD) emergency department. Participants were one hundred seventeen children without any chronic illness between 2 5 years presenting to OPD, having for <48 h with mild moderate dehydration, not antibiotics requiring oral rehydration therapy. Intervention done was DS dose 1.5 g...
Panayiotopoulos syndrome is early-onset benign childhood epilepsy, now classified as an electroclinical syndrome. The original description in 1989 focused on the triad of nocturnal seizures, tonic eye deviation, and vomiting. With available data from long-term studies, a wide variety manifestations have been described, with recognition autonomic features being most prominent aspect this epilepsy. presenting symptoms are usually focal seizures comprising and/or behavioral changes. Majority...
Bronchiolitis is a self-limiting disease of children caused by viral infections the small airways with wide spectrum illness severity. Search literature reveals need for refinement criteria testing concomitant severe bacterial as well appropriate therapeutic interventions patients <90-day-old diagnosed clinical bronchiolitis. We believe that better understanding will help optimize health-care delivery to these patients.The aim this study was determine profile at presentation, course and...
Procedural sedation and analgesia (PSA) has become the standard of care for diagnostic therapeutic procedures undertaken in Emergency Department (ED). In Pediatric (PED) King Khalid University Hospital (KKUH), which is a major teaching hospital Riyadh Kingdom Saudi Arabia we developed protocol PSA since 2005. The aim this article to report experience at KKUH pediatric PSA.To PSA.Retrospective cross-sectional study all cases who underwent painful from December 2005 July 2008.A total 183...
Lisuride Maleate (Dopergin) is semi synthetic ergot alkaloid used for a variety of medical conditions. It licensed use in Canada, EU and Middle East countries marketed by various drug companies. There are no reported cases lisuride toxicity the literature on Google Search or Pub med Search.Herein, we present case accidental overdose maleate 21-month-old Saudi male further clinical course management. The aim this report was to document unusual features pediatric patients guide physicians its
Ahmad, Syed Amir MD; Mujawar, Quais Bawardi, Nazek A. MDEditor(s): Osterhoudt, Kevin C. MD Author Information
<h3></h3> Real-world evidence (RWE) analytics continue to advance natural history comparisons in rare diseases. The Global Alagille Alliance (GALA) is the largest global clinical research database for syndrome (ALGS). Maralixibat (MRX) an ileal bile acid transporter inhibitor approved by FDA treatment of cholestatic pruritus patients with ALGS ≥1 year age. A pre-specified analysis plan applied novel analytical techniques compare RWE from GALA a MRX cohort aim event-free survival (EFS) ALGS....