A5062848036- Acute Myeloid Leukemia Research
- Histone Deacetylase Inhibitors Research
- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- Immune cells in cancer
- Kruppel-like factors research
- Neonatal Health and Biochemistry
- Religion, Spirituality, and Psychology
- Nanoparticle-Based Drug Delivery
- Immune Cell Function and Interaction
- Parvovirus B19 Infection Studies
- Autoimmune and Inflammatory Disorders Research
- Hematopoietic Stem Cell Transplantation
- Neutropenia and Cancer Infections
- Myeloproliferative Neoplasms: Diagnosis and Treatment
Dalian Medical University
2022-2025
Chongqing Medical University
2022-2025
Second Affiliated Hospital of Chongqing Medical University
2022-2025
Background Effective treatment options are limited for elderly patients with acute myeloid leukemia (AML). A prospective phase II study was conducted to investigate the safety and efficacy of pegylated liposomal doxorubicin (PLD) combined low-dose cytarabine (LDAC) granulocyte colony-stimulating factor (G-CSF) in newly diagnosed older unfit AML patients. Methods Twenty-two were enrolled deemed evaluable. The included one cycle induction four cycles consolidation, followed by maintenance...
Abstract Inherited anemia continues to pose a significant public health concern on global scale, owing its extensive geographical prevalence, substantial patient population, and profound ramifications. Here, we investigated detailed information inherited anemias (including thalassemias, thalassemias trait, sickle cell disease, G6PD deficiency, trait) for the period 1990–2019 from Global Burden of Disease study. Over course three decades, there has been persistent rise in incidence worldwide,...
Abstract Background To assess the prevalence trend and contributing factors of heart failure (HF) impairment with thalassemias at global, regional national levels. Methods Data on HF was collected from Global Burden Disease study. The absolute number disease were systematically for each year, estimated annual percentage changes (EAPC) in calculated by gender, region country to measure temporal trends. Results Thalassemias have caused a significant global burden since 1990, case related has...
Background.Acute myeloid leukemia (AML) is a heterogeneous disease characterized by diverse genetic abnormalities.The NPM1 the most commonly mutated gene in newly diagnosed patients.Optimizing risk stratification this population could facilitate more rational clinical decision-making.Objectives.To identify biomarkers that optimize AML patients with mutations. Materials and methods.Acute from multiple centers were included study.Univariate, multivariate Kaplan-Meier survival analyses used to...
Abstract Purpose CD200, a trans-membrane protein belonging to the immunoglobulin superfamily, has been associated with poor prognosis in acute myeloid leukemia(AML). We aimed analyze correlations between CD200 expression and prognostic significance AML patients. Methods retrospectively reviewed 160 patients evaluating impact of on complete remission (CR), disease free survival(DFS), overall survival (OS) our institution 2018 2021. Results were expressed 100/160 (62.5%) cases, which defined...