A5058523182- Tryptophan and brain disorders
- Higher Education and Teaching Methods
- Neurological Disease Mechanisms and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Stress Responses and Cortisol
- Neurological disorders and treatments
- Resilience and Mental Health
- Medicinal Plants and Neuroprotection
- COVID-19 and Mental Health
- Parkinson's Disease Mechanisms and Treatments
- COVID-19 diagnosis using AI
- Vagus Nerve Stimulation Research
- Healthcare professionals’ stress and burnout
- Elder Abuse and Neglect
- Health and Wellbeing Research
- Biochemical effects in animals
- Outsourcing and Supply Chain Management
- Functional Brain Connectivity Studies
- Mindfulness and Compassion Interventions
- Education and Work Dynamics
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Workplace Violence and Bullying
- Efficiency Analysis Using DEA
- Sirtuins and Resveratrol in Medicine
- Medicinal Plants and Bioactive Compounds
Nanjing Medical University
2024-2025
Jiangsu Province Hospital
2024-2025
Wuhan University
2012-2024
Zhongnan Hospital of Wuhan University
2012-2024
Peking University
2023
Nanjing General Hospital of Nanjing Military Command
2011-2022
National Clinical Research
2022
Longgang Central Hospital
2019
Beihua University
2016-2017
Air Force Medical University
2014
In December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province; and then named "2019 novel coronavirus (2019-nCoV)" by the World Health Organization (WHO) on 12 January 2020. For it is never been experienced respiratory disease before with infection ability widely quickly, attracted world's attention but without treatment control manual. request from frontline clinicians public health professionals of 2019-nCoV infected management, an evidence-based guideline urgently...
An enriched environment (EE) is beneficial in modifying behaviors, particularly tasks involving complex cognitive functions. However, the impact of EE on impairment induced by chronic cerebral hypoperfusion (CCH) has not been studied. We investigated effects caused CCH and examined whether altered protein levels brain-derived neurotrophic factor (BDNF) N-methyl-D-aspartate (NMDA) receptor subunit 1 (NR1) 2B (NR2B) hippocampus rats exposure attenuated effects. Rats were divided into four...
To investigate psychological status, coping, social support, and psychosocial factors associated with people living HIV/AIDS in a highly HIV-infected area of central China.Cross-sectional descriptive correlation study.Of 200 individuals registered at the "Warm Homestead" health care center (central China), all who met eligibility criteria (n=103) were recruited; 94 these completed questionnaires.Four anonymous self-administered questionnaires used: (a) demographic data questionnaire, (b)...
Objective To explore the abuse risk and related important determinants among older people with dementia in central China. Methods In this cross‐sectional descriptive study, a sample of 158 family caregivers was conveniently recruited from Clinical Medicine Research Center Dementia Cognitive Impairment Hubei Province, A social‐demographic questionnaire, Simplified Coping Style Questionnaire (SCSQ), Social Support Rating Scale (SSRS), Caregiver Burden Inventory (CBI), Abuse Screen (CASE) were...
To investigate the experience and support of nurses as second victims in adverse events explore factors.Adverse have significant negative influences on healthcare professionals. However, there is still a lack research impacts individual event factors.A cross-sectional survey via self-report electronic questionnaire was sent to approximately 6400 from six tertiary comprehensive hospitals mainland China. The socio-demographic, event-related information second-victim questionnaires were...
Our study aimed to investigate the neural mechanisms of taVNS in motor symptoms PD, focusing on topological properties cortical functional networks and excitability. Thirty-two PD patients underwent near‐infrared spectroscopy transcranial magnetic stimulation evaluation prior after two-week taVNS, which were controlled by 20 healthy controls (HCs). exhibited decreased nodal efficiency (Ne) right M1 increased Ne left pre‐motor supplementary area compared with HCs. The was negatively...
Chronic stress can cause emotional dysfunction, but exposure to an enriched environment (EE) benefit homeostasis. Recent studies have demonstrated that EE ameliorate stress-induced depressive-like behaviors. Whether hypothalamic-pituitary-adrenal (HPA) axis activity and corticosteroid receptors are involved in these effects of is not known. In our current study, we examined HPA hippocampal mineralocorticoid receptor/glucocorticoid receptor (MR/GR) mRNA levels following chronic rats. Our...
Neuropsychiatric symptoms (including anxiety, depression, apathy, impulse-compulsive behaviors and hallucinations) are among the most common non-motor features of Parkinson's disease. Whether these should be considered as a direct consequence pathophysiologic mechanisms disease is controversial. Morphometric similarity network analysis epicenter mapping approach were performed on T1-weighted images 505 patients with 167 age- sex-matched healthy participants from Progression Markers...
The accumulation of chronic stress is associated with cognitive dysfunction. Radix Angelica Sinensis (RAS) has been shown to have neuroprotective potential for treating Alzheimer's disease and vascular dementia. However, the impact RAS on impairment induced by not studied. In present study, significantly alleviated deficits in rats subjected restraint stress. This effect was enhancement synaptic efficacy improving field excitatory postsynaptic amplitudes, alleviating adverse alterations...
The incidence of allergic rhinitis in children is high across the world, as well China. Allergic has serious impact on physical and mental health children. At same time, caregivers have heavy burden care, their problems are severe. It necessary to implement timely psychological intervention for Mindfulness-Based Cognitive Therapy (MBCT) a safe effective therapy, effect online can be comparable traditional face-to-face program. This study focused status main with rhinitis, conducted modified...
This study was to investigate the association between character strengths and job crafting among nurses in tertiary hospitals China.A cross-sectional survey conducted.From February 2021 April 2021, 1006 from four China were recruited complete a series of online questionnaires assessing their strengths. The analysis conducted using structural equation modelling (SEM).The mean scores for task crafting, cognitive relationship 3.19 ± 0.58, 3.50 0.55 3.58 0.51. There is moderate level Chinese...
Abstract PM 2.5 components may promote the development of breast cancer and increase risk mortality. This study aims to investigate associations between long-term exposure multiple causes mortality among women with living in Inner Mongolia, China. We constructed an Mongolia cohort 33 952 patients from 2012 2021 using data Regional Health Information Platform. assessed each patient’s Tracking Air Pollution China database. Cox regression models were used estimate adjusted hazard ratios 95%...
Severe acute respiratory syndrome (SARS) first emerged in Guangdong on November 16, 2002, and subsequently spread to Hong Kong, Beijing, Taiwan, other areas. According WHO, 8 098 cases were reported 29 countries.1,2 Although researchers around the world have been carrying out extensive studies for 10 years, reservoir of SARS coronavirus (CoV) has not found.1,3-18 At beginning, a virus sharing 99.8% homology with CoV was found Himalayan palm civet (Paguma larvata).10 However, it is...
Abstract Background Cyclooxygenase‐2 (COX‐2) is an inducible enzyme with catalytic activity for biosynthesis of prostaglandins which are the key mediators inflammation. COX‐2 also therapeutic target widely used non‐steroidal anti‐inflammatory drugs (NSAIDs). However, involvement in xenotransplantation (eg, pig‐to‐non‐human primate) remains poorly recognized. Methods We investigated mechanisms that regulate expression and effects on porcine aortic endothelial cell (PAEC) viability using vitro...
Choice of logistics distribution center is classified to qualitative analysis and quantitative analysis, this paper adopted the Delphi method analytic hierarchy process make research on problem choice solve it, based thought scale economy theory. At same time ensuring satisfy demand in zone, it plots out zone which needs be supplied service order avoid repeated computation cost service, decrease difficulty data investigation. It becomes easier adopt mode seek for an answer, also puts forward...