- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Bariatric Surgery and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Diet and metabolism studies
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Esophageal and GI Pathology
- Organ Transplantation Techniques and Outcomes
- Biliary and Gastrointestinal Fistulas
- Multiple and Secondary Primary Cancers
- Obesity and Health Practices
- Enhanced Recovery After Surgery
- Pediatric Hepatobiliary Diseases and Treatments
- Nutrition and Health in Aging
- Hemodynamic Monitoring and Therapy
- Central Venous Catheters and Hemodialysis
- Colorectal Cancer Surgical Treatments
- Renal cell carcinoma treatment
- Genetic and Kidney Cyst Diseases
- Helicobacter pylori-related gastroenterology studies
- Adipokines, Inflammation, and Metabolic Diseases
Vita-Salute San Raffaele University
2013-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2009-2022
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2008-2022
IRCCS Ospedale San Raffaele
2004-2020
Philadelphia University
2013
RELX Group (United States)
2013
Fondazione Idis Città della Scienza
2004-2012
University of Milan
2001-2002
San Raffaele University of Rome
1993-2000
Laparoscopy is gaining acceptance as a safe procedure for resection of liver neoplasms. The aim this study to evaluate surgical results and mid-term survival minor hepatic performed HCC.Data 16 patients with HCC, undergoing laparoscopic hepatectomy from September 2005 January 2009, were compared control group who underwent open (OR) during the same period. two groups matched in terms type resection, tumor size, severity cirrhosis.One patient conversion an approach. Laparoscopic approach...
Weight loss ameliorates arterial hypertension and glucose metabolism in obese patients, but the dietary approach is unsatisfactory because obesity relapses. Durable reduction of body weight, obtained through major nonreversible surgical procedures, such as jejunal gastric bypass, allows improvement blood pressure morbid (grade 3) obesity. Laparoscopic adjustable banding (LAGB) a minimally invasive reversible procedure that yields significant volume hunger sensation. In this study, 143...
OBJECTIVE—Lifestyle modifications and pharmacological interventions can prevent type 2 diabetes in obese subjects with impaired glucose tolerance. The aim of this study was to compare laparoscopic adjustable gastric banding (LAGB) conventional diet (No-LAGB) the prevention (primary intervention study; 56 vs. 29 patients) remission (secondary 17 20 hypertension grade 3 obesity a 4-year study. RESEARCH DESIGN AND METHODS—The (n = 122; age 48.5 ± 1.05 years; BMI 45.7 0.67 kg/m2) underwent...
Abstract Context: Obesity is frequently associated with left ventricular hypertrophy, even when uncomplicated by hypertension or diabetes mellitus. Left hypertrophy an important risk factor for congestive heart failure. Objective: The objective of this study was to evaluate the relationship between leptin and mass in uncomplicated, morbid (grade 3) obesity existence receptors intracellular signaling proteins human heart. Design: (LVM) calculated through electrocardiogram reading normotensive...
Surgery represents the mainstay treatment of colorectal liver metastases. Indications for laparoscopic approach in this setting have been widened and there is a need to confirm benefits minimally invasive surgery (MILS) patients with complex disease states.To compare outcomes those open metastases from cancer, focusing on characteristics modern MILS therefore overcoming possible selection bias related different policies patients' eligibility over time.A cohort study 885 resections performed...
Uncoupling protein (UCP)-2 is a member of the mitochondrial inner membrane carriers that uncouple pro-ton entry in matrix from ATP synthesis. The −866G/A polymorphism UCP2 gene, which enhances its transcriptional activity, was associated with enhanced risk for type 2 diabetes obese subjects. We addressed question whether contributes to variation insulin sensitivity by genotyping 181 nondiabetic offspring diabetic patients. Insulin sensitivity, assessed hyperinsulinemic-euglycemic clamp,...
Studies on thyroid function in obesity yielded inconsistent results; high thyroid-stimulating hormone (TSH) levels were generally shown; free triiodothyronine (fT)-3 or fT4 described some, but not other studies. After weight loss, TSH and hormones have been to either increase decrease. Our aim was describe TSH, fT3, obese subjects with normal before after durable significant obtained through laparoscopic gastric banding (LAGB), comparison nonobese subjects. fT4, fT3/fT4 ratio (an index of D1...
OBJECTIVE—The C-174G promoter polymorphism of the interleukin (IL)-6 gene was found to influence transcriptional activity and plasma IL-6 levels in humans. We addressed question whether contributes variation insulin sensitivity. RESEARCH DESIGN AND METHODS—Two cohorts subjects were genotyped. Cohort 1 includes 275 nondiabetic who underwent a euglycemic-hyperinsulinemic clamp. 2 77 patients with morbid obesity laparoscopic adjustable gastric banding (LAGB). RESULTS—The genotypes consistent...