- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Neurotoxicity Research
- Anesthesia and Pain Management
- Machine Learning in Healthcare
- Pain Management and Opioid Use
- Privacy-Preserving Technologies in Data
- Airway Management and Intubation Techniques
- Nausea and vomiting management
- Cardiac Imaging and Diagnostics
- Respiratory Support and Mechanisms
- Hemodynamic Monitoring and Therapy
- Lung Cancer Diagnosis and Treatment
- Neuropeptides and Animal Physiology
- Pain Mechanisms and Treatments
- Enhanced Recovery After Surgery
- Neuroinflammation and Neurodegeneration Mechanisms
- Analytical chemistry methods development
- Atrial Fibrillation Management and Outcomes
- Artificial Intelligence in Healthcare and Education
- Patient Safety and Medication Errors
- Neonatal and fetal brain pathology
- Statistical Methods and Bayesian Inference
- Sepsis Diagnosis and Treatment
Massachusetts General Hospital
2016-2025
Harvard University
2016-2025
Sichuan University
2022-2025
Qingdao University
2025
Affiliated Hospital of Qingdao University
2025
West China Hospital of Sichuan University
2022-2025
Hunan University of Finance and Economics
2024-2025
Guangzhou University of Chinese Medicine
2024
Guangdong-Hongkong-Macau Joint Laboratory of Collaborative Innovation for Environmental Quality
2024
Pain and Rehabilitation Medicine
2024
Opioids administered to treat postsurgical pain are a major contributor the opioid crisis, leading chronic use in considerable proportion of patients. Initiatives promoting opioid-free or opioid-sparing modalities perioperative management have led reduced administration operating room, but this reduction could unforeseen detrimental effects terms postoperative outcomes, as relationship between intraoperative usage and later requirements is not well understood.To characterize association...
Intensive care data are valuable for improvement of health care, policy making and many other purposes. Vast amount such stored in different locations, on devices silos. Sharing among sources is a big challenge due to regulatory, operational security reasons. One potential solution federated machine learning, which method that sends learning algorithms simultaneously all sources, trains models each source aggregates the learned models. This strategy allows utilization without moving them....
BACKGROUND: A number of recent studies have reported an association between intraoperative burst suppression and postoperative delirium. These suggest that anesthesia-induced may be indicator underlying brain vulnerability. prominent feature electroencephalogram (EEG) under propofol sevoflurane anesthesia is the frontal alpha oscillation. This oscillation known to decline significantly during aging generated by prefrontal regions are particularly prone age-related neurodegeneration. Given...
Postoperative residual neuromuscular blockade continues to be a frequent occurrence with reported incidence rate of up 64%. However, the effect postoperative on health care utilization remains unclear. We conducted retrospective cohort study investigate effects hospital costs (primary outcome), intensive unit admission rate, and length stay (secondary outcomes).
China’s total carbon emissions account for one-third of the world’s total. How to reach peak by 2030 and achieve neutrality 2060 is an important policy orientation at present. Therefore, it great significance analyze characteristics driving factors temporal spatial evolution on basis effective calculation prediction in various provinces promoting high-quality economic development realizing emission reduction. Based energy consumption data 30 China from 2000 2021, this paper calculates...
Calabadion 2 is a new drug-encapsulating agent. In this study, the authors aim to assess its utility as an agent reverse general anesthesia with etomidate and ketamine facilitate recovery.To evaluate effect of calabadion on recovery, studied response rats after continuous bolus intravenous or intramuscular administration. The measured electroencephalographic predictors depth (burst suppression ratio total power), functional mobility impairment, blood pressure, toxicity.Calabadion...
Introduction Delirium, which is prevalent in postcardiac surgical patients, an acute brain dysfunction characterised by disturbances attention, awareness and cognition not explained a pre-existing neurocognitive disorder. The pathophysiology of delirium remains poorly understood. However, basic science clinical studies suggest that sleep disturbance may be modifiable risk factor for the development delirium. Dexmedetomidine α-2A adrenergic receptor agonist medication patterns activity...
BACKGROUND: Pneumoperitoneum and nonphysiological positioning required for robotic surgery increase cardiopulmonary risk because of the use larger airway pressures (Paws) to maintain tidal volume (V t ). However, quantitative partitioning respiratory mechanics transpulmonary pressure (P l ) during is not well described. We tested following hypothesis: (1) components driving (transpulmonary chest wall components) in a parallel fashion at surgical stages (Trendelenburg robot docking); (2)...
Abstract Diabetic periodontitis presents a unique therapeutic challenge, primarily due to its chronic inflammatory profile and the associated bone loss driven by immune dysregulation. Metformin (Met) is recognized for potent anti‐inflammatory properties, yet limited cellular uptake has hindered clinical effectiveness in diabetic periodontitis. A tetrahedral framework nucleic acid (tFNA)‐based delivery system developed enhance Met investigate effects on this study. The tFNA‐loaded complex...
Background Abdominal aortic calcification (AAC), an early indicator of abdominal wall atherosclerosis, is a marker subclinical atherosclerosis and predictive factor for vascular-associated morbidity mortality. These outcomes are driven by inflammatory processes. Given the pivotal role mediators in pathogenesis calcification, inflammation has attracted interest as peripheral biomarker mortality prediction patients with calcification. The neutrophil-to-lymphocyte ratio (NLR) measured blood...
<ns3:p>Background At the 2020 UN General Assembly, China pledged to peak carbon emissions before 2030 and achieve neutrality by 2060. However, traditional social development model has led increasing annually, highlighting need resolve contradiction between reduction. This study examines relationship emissions, economy, population, energy consumption in a specific region support goals. Methods A comprehensive indicator system was established, encompassing economic, consumption, indicators....
The health care systems in low-income countries have extremely limited capacity to treat surgical diseases. perioperative mortality rate has been suggested as a key quality metric guide the expansion of care, but there is little information on how risk-adjust this outcome measure. We did 42-month observational cohort study operations at Ugandan secondary referral hospital. examined factors associated with in-hospital 30-day outcomes. aim was suggest suitable indicator for comparative service...
<ns3:p>Background At the 2020 UN General Assembly, China pledged to peak carbon emissions before 2030 and achieve neutrality by 2060. However, traditional social development model has led increasing annually, highlighting need resolve contradiction between reduction. This study examines relationship emissions, economy, population, energy consumption in a specific region support goals. Methods A comprehensive indicator system was established, encompassing economic, consumption, indicators....