A5022027632- Digital Radiography and Breast Imaging
- Radiation Dose and Imaging
- Medical Imaging Techniques and Applications
- Lung Cancer Diagnosis and Treatment
- Advanced X-ray and CT Imaging
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Cardiovascular Function and Risk Factors
- Radiomics and Machine Learning in Medical Imaging
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Radiology practices and education
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Advanced MRI Techniques and Applications
- Respiratory Support and Mechanisms
- Aortic Disease and Treatment Approaches
- Asthma and respiratory diseases
- Peripheral Artery Disease Management
- Acute Ischemic Stroke Management
- Oral health in cancer treatment
- Cerebrovascular and Carotid Artery Diseases
- Esophageal Cancer Research and Treatment
- Colorectal Cancer Screening and Detection
- Esophageal and GI Pathology
- Inflammasome and immune disorders
- Cardiovascular Disease and Adiposity
Sahlgrenska University Hospital
2015-2025
Region Västra Götaland
2019-2025
University of Gothenburg
2015-2024
Institute of Clinical Research
2016
Abstract Cardiopulmonary diseases are major causes of death worldwide, but currently recommended strategies for diagnosis and prevention may be outdated because recent changes in risk factor patterns. The Swedish CArdioPulmonarybioImage Study (SCAPIS) combines the use new imaging technologies, advances large‐scale ‘omics’ epidemiological analyses to extensively characterize a cohort 30 000 men women aged between 50 64 years. information obtained will used improve prediction cardiopulmonary...
Purpose: To compare chest tomosynthesis with radiography in the detection of pulmonary nodules by using multidetector computed tomography (CT) as reference method. Materials and Methods: The Regional Ethical Review Board approved this study, all participants gave informed consent. Four thoracic radiologists acted observers a jackknife free-response receiver operating characteristic (JAFROC) study conducted 42 patients 47 without examined radiography. Multidetector CT served marked suspected...
Background: Spirometric diagnosis of chronic obstructive pulmonary disease (COPD) is based on the ratio forced expiratory volume in 1 second (FEV )/vital capacity (VC), either as a fixed value <0.7 or below lower limit normal (LLN). Forced vital (FVC) proxy for VC. The first aim was to compare use FVC and VC, assessed highest slow (SVC), when assessing FEV /VC general population setting. evaluate characteristics subjects with COPD who obtained higher SVC than FVC. Methods: Subjects (n=1,050)...
To validate a deep-learning (DL) algorithm for automated quantification of prostate cancer on positron emission tomography/computed tomography (PET/CT) and explore the potential PET/CT measurements as prognostic biomarkers.Training DL-algorithm regarding volume was performed manually segmented CT images in 100 patients. Validation carried out 45 patients with biopsy-proven hormone-naïve cancer. The were compared manual made independently by two observers. tumour burden based SUV abnormal...
The new technique chest tomosynthesis refers to the principle of collecting low-dose projections at different angles and using these reconstruct section images a radiation dose comparable that radiography.To investigate if, for experienced thoracic radiologists, detectability pulmonary nodules obtained after only short initial learning period improves with additional clinical experience technique.Two readings same cases, first performed 6 months second an 1 year, were conducted. Three senior...
Summary Background Oesophageal cancer is often diagnosed at an advanced stage, with poor prognosis and severe morbidity. In majority of cases, palliative treatment the only option available. Aim To find factors that can predict survival for patients incurable oesophagus or gastro‐oesophageal junction hence aid in choice treatment. Methods Ninety‐six were included. Health‐related quality life questionnaires (EORTC QLQ C‐30 OES18) administered computerized tomography‐derived size assessment...
The recent implementation of chest tomosynthesis is built on the availability large, dose-efficient, high-resolution flat panel detectors, which enable acquisition necessary number projection radiographs to allow reconstruction section images within one breath hold. A examination obtains increased diagnostic information provided by volumetric imaging at a radiation dose comparable that conventional radiography. There evidence sensitivity may be least three times higher than for radiography...
Since December 2006, ∼3800 clinical chest tomosynthesis examinations have been performed at our department Sahlgrenska University Hospital. A subset of the has included in studies detectability pulmonary nodules, using computed tomography (CT) as gold standard. Visibility studies, which and CT compared side-by side, used to determine depiction potential tomosynthesis. Comparisons with conventional radiography made. In setting, mostly an additional examination. The most frequent indication...
To evaluate intra- and interobserver variability, as well agreement for nodule size measurements on chest tomosynthesis computed tomographic (CT) images.The Regional Ethical Review Board approved this study, all participants gave written informed consent. Thirty-six segmented nodules in 20 patients were included the study. Eight observers measured left-to-right, inferior-to-superior, longest diameters CT images. Intra- repeatability, between images, assessed recommended by Bland Altman.The...
In chest tomosynthesis, low-dose projections collected over a limited angular range are used for reconstruction of an arbitrary number section images the chest, resulting in moderately increased radiation dose compared to radiography.To investigate effects learning with feedback on detection pulmonary nodules observers varying experience identify pitfalls regarding nodules, and present suggestions how avoid them, adapt European quality criteria radiography computed tomography (CT)...
Interstitial lung abnormalities (ILA) are incidental findings on chest computed tomography (CT). These patterns can present at an early stage of fibrotic disease. Our aim was to estimate the prevalence ILA in Swedish population, particular never-smokers, and find out its association with demographics, comorbidities symptoms.Participants were recruited CArdioPulmonary BioImage Study (SCAPIS), a population-based survey including men women aged 50-64 years performed six university hospitals...
Background Preserved ratio impaired spirometry (PRISm) is a pattern of interest regarding incident airflow obstruction and higher mortality risk. We applied proteomic approach to gain more insight into the biological mechanisms associated with PRISm. Methods From population-based Swedish CArdioPulmonary bioImage Study (SCAPIS), participants in Main (n=4835) Pilot (n=1054) studies, were included as discovery replication cohorts. Lower limit normal (LLN) post-bronchodilator FEV 1 , FVC /FVC...
Journal Article Nodule detection in digital chest radiography: effect of system noise Get access Markus Håkansson, Håkansson *Corresponding author: markus.hakansson@vgregion.se Search for other works by this author on: Oxford Academic PubMed Google Scholar Magnus Båth, Båth Sara Börjesson, Börjesson Susanne Kheddache, Kheddache Åse Allansdotter Johnsson, Johnsson Lars Gunnar Månsson Radiation Protection Dosimetry, Volume 114, Issue 1-3, 17 May 2005, Pages 97–101,...
This study contributes to social studies of imaging and visualization practices within scientific medical settings. The focus is on in radiology, which are bound up with visual records known as radiographs. addresses work following the introduction a new technology, tomosynthesis. Since it was novel there limited knowledge how correctly analyse tomosynthesis images. To address this problem, collective review session arranged. purpose present uncover practical that took place during show how,...
Purpose: To investigate the potential benefit of increasing dose per projection image in chest tomosynthesis, performed at current standard level, by reducing angular range covered or density and to evaluate influence tube voltage on quality. Methods: An anthropomorphic phantom was imaged using nine different configurations ten voltages with GE VolumeRAD tomosynthesis system. The resulting sets were representative being acquired same total effective dose. This achieved partly applying a...
The aim of the present study was to investigate nodule size measurements with chest tomosynthesis (TS) and computed tomography (CT). A 26-mm thick phantom, composed a Polylite block embedded spheres different materials sizes (4–20 mm), scanned by both CT TS. Six observers without prior knowledge true diameters independently measured diameter on TS images. Four were allowed change window settings two used predetermined fixed viewing conditions. mean relative errors for all compared known 1.4...
To investigate the accuracy and precision of pulmonary nodule size measurements on chest tomosynthesis images.Artificial ellipsoid-shaped nodules with known sizes were inserted in clinical images. The volume corresponded to that a sphere diameter 4.0, 8.0, or 12.0 mm. Four thoracic radiologists given task determine longest nodules. All measured twice. Measurement terms mean measurement error was determined. Intraobserver interobserver variabilities, as well variability because differences...
Rationale and ObjectivesEmphysema is a hallmark of chronic obstructive pulmonary disease. The primary aim this study was to investigate inter- intraobserver agreement visual assessment mild emphysema in low-dose multidetector computed tomography subjects the pilot SCAPIS order certify consistent detection emphysema. secondary performance quantitative densitometric measurements cohort.Materials MethodsParticipants with (n = 100, 56 males 44 females) reported electronic case report form 100...
There is no established technique that directly quantifies lower limb tissue perfusion. Blood oxygenation level-dependent magnetic resonance imaging (BOLD-MRI) an MRI can determine skeletal muscle BOLD-MRI relies on differences of oxygenated and deoxygenated hemoglobin, regional changes in oxy/deoxyhemoglobin ratio be recorded by T2* weighted sequences. We aimed to test whether differentiate perfusion peripheral arterial occlusive disease (PAOD) patients healthy controls. Twenty-two PAOD ten...