- Pharmaceutical and Antibiotic Environmental Impacts
- Environmental Toxicology and Ecotoxicology
- Toxic Organic Pollutants Impact
- Effects and risks of endocrine disrupting chemicals
- Metabolomics and Mass Spectrometry Studies
- Pesticide and Herbicide Environmental Studies
- Advanced Chemical Sensor Technologies
- Analytical chemistry methods development
- Analytical Chemistry and Chromatography
- Mass Spectrometry Techniques and Applications
- Water Quality Monitoring and Analysis
- Carcinogens and Genotoxicity Assessment
- Pesticide Residue Analysis and Safety
- Water Treatment and Disinfection
- Isotope Analysis in Ecology
- Water Quality and Pollution Assessment
- Acute Ischemic Stroke Management
- Health, Environment, Cognitive Aging
- Insect and Pesticide Research
- Microbial bioremediation and biosurfactants
- Aquatic Ecosystems and Phytoplankton Dynamics
- Environmental Chemistry and Analysis
- Aluminum Alloys Composites Properties
- Microplastics and Plastic Pollution
- Magnesium Alloys: Properties and Applications
Helmholtz Centre for Environmental Research
2016-2025
University of Otago
2020-2023
University of Gothenburg
2023
Christchurch Hospital
2015-2022
Universitäres Zentrum für Zahnmedizin Basel
2019-2022
University of Kassel
2001-2019
World Health Organization Regional Office for Europe
2012-2018
Swiss Federal Institute of Aquatic Science and Technology
2008-2017
KraussMaffei (Germany)
2015
Viessmann (Germany)
2012
The removal efficiency for 220 micropollutants was studied at the scale of a municipal wastewater treatment plant (WWTP) upgraded with post-ozonation followed by sand filtration. During post-ozonation, compounds activated aromatic moieties, amine functions, or double bonds such as sulfamethoxazole, diclofenac, carbamazepine second-order rate constants reaction ozone >104 M−1 s−1 pH 7 (fast-reacting) were eliminated to concentrations below detection limit an dose 0.47 g O3 g−1 dissolved...
Environmental water quality monitoring aims to provide the data required for safeguarding environment against adverse biological effects from multiple chemical contamination arising anthropogenic diffuse emissions and point sources. Here, we integrate experience of international EU-funded project SOLUTIONS shift focus a few legacy chemicals complex mixtures, identify relevant drivers toxic effects. Monitoring serves range purposes, control ecological status compliance specific uses, such as...
Surface water can contain countless organic micropollutants, and targeted chemical analysis alone may only detect a small fraction of the chemicals present. Consequently, bioanalytical tools be applied complementary to effects complex mixtures. In this study, bioassays indicative activation aryl hydrocarbon receptor (AhR), pregnane X (PXR), estrogen (ER), adaptive stress responses oxidative (Nrf2), genotoxicity (p53) inflammation (NF-κB) fish embryo toxicity test were along with extracts...
Large-scale suspect and non-targeted screening approaches based on high-resolution mass spectrometry (HRMS) are today available for chemical profiling holistic characterisation of biological samples. These advanced techniques allow the simultaneous detection a large number features, including markers human exposure. Such interest biomonitoring, environmental health studies support to risk assessment. Furthermore, these have promising capability detect chemicals emerging concern (CECs),...
Non-target screening (NTS) including suspect with high resolution mass spectrometry has already shown its feasibility in detecting and identifying emerging contaminants, which subsequently triggered exposure mitigating measures. NTS a large potential for tasks such as effective evaluation of regulations safe marketing substances products, prioritization monitoring programmes assessment environmental quality. To achieve this, further development methodology is required, including: (i)...
There is an increasing need for comparable and harmonized retention times (tR) in liquid chromatography (LC) among different laboratories, to provide supplementary evidence the identity of compounds high-resolution mass spectrometry (HRMS)-based suspect nontarget screening investigations. In this study, a rigorously tested, flexible, less system-dependent unified time index (RTI) approach LC presented, based on calibration elution pattern. Two sets 18 calibrants were selected each ESI+...
Abstract Increasing production and use of chemicals awareness their impact on ecosystems humans has led to large interest for broadening the knowledge chemical status environment human health by suspect non-target screening (NTS). To facilitate effective implementation NTS in scientific, commercial governmental laboratories, as well acceptance managers, regulators risk assessors, more harmonisation is required. address this, NORMAN Association members involved activities have prepared this...
Abstract Background The NORMAN Association ( https://www.norman-network.com/ ) initiated the Suspect List Exchange (NORMAN-SLE; https://www.norman-network.com/nds/SLE/ in 2015, following collaborative trial on non-target screening of environmental water samples by mass spectrometry. Since then, this exchange information chemicals that are expected to occur environment, along with accompanying expert knowledge and references, has become a valuable base for “suspect screening” lists....
In this study, 56 effluent samples from 52 European wastewater treatment plants (WWTPs) were investigated for the occurrence of 499 emerging chemicals (ECs) and their associated potential risks to environment. The two main objectives (i) extend our knowledge on occurring in treated wastewater, (ii) identify prioritize compounds concern based three different risk assessment approaches identification consensus mixture drivers concern. Approaches include PNEC EQS-based regulatory quotients...
Background: An association between exposure to environmental tobacco smoke (ETS) and lung cancer risk has been suggested. To evaluate this possible better, researchers need more precise estimates of risk, the relative contribution different sources ETS, effect ETS on histologic types cancer. address these issues, we have conducted a case-control study in 12 centers from seven European countries. Methods: A total 650 patients with 1542 control subjects up 74 years age were interviewed about...