- Environmental Toxicology and Ecotoxicology
- Agricultural safety and regulations
- Pesticide and Herbicide Environmental Studies
- Insect and Pesticide Research
- Pesticide Residue Analysis and Safety
- Pharmaceutical and Antibiotic Environmental Impacts
- Insect and Arachnid Ecology and Behavior
- Plant and animal studies
- Water Quality and Pollution Assessment
- Toxic Organic Pollutants Impact
- Pesticide Exposure and Toxicity
- Fish Ecology and Management Studies
- Insect Pest Control Strategies
- Microbial Community Ecology and Physiology
- Environmental Science and Water Management
- Species Distribution and Climate Change
- Antibiotics Pharmacokinetics and Efficacy
- Antibiotic Resistance in Bacteria
- Insect-Plant Interactions and Control
- Aquatic Invertebrate Ecology and Behavior
- Agriculture, Soil, Plant Science
- Forest Insect Ecology and Management
- Effects and risks of endocrine disrupting chemicals
- Environmental Chemistry and Analysis
- Animal testing and alternatives
Osnabrück University
2008-2025
Wageningen University & Research
2013-2023
Altera (United States)
2020
Netherlands Institute of Ecology
2013
The European Commission asked EFSA to revise the risk assessment for honey bees, bumble bees and solitary bees. This guidance document describes how perform from plant protection products, in accordance with Regulation (EU) 1107/2009. It is a review of EFSA's existing document, which was published 2013. outlines tiered approach exposure estimation different scenarios tiers. includes hazard characterisation provides methodology covering dietary contact exposure. also recommendations higher...
Summary Crucial steps in geochemical cycles are many cases performed by more than one group of microorganisms, but the significance this functional redundancy with respect to ecosystem functioning is poorly understood. Ammonia‐oxidizing archaea (AOA) and their bacterial counterparts (AOB) a perfect system address question: although performing same transformation step, they belong well‐separated phylogenetic groups. Using pig manure amended different concentrations sulfadiazine (SDZ), an...
Environmental water quality monitoring aims to provide the data required for safeguarding environment against adverse biological effects from multiple chemical contamination arising anthropogenic diffuse emissions and point sources. Here, we integrate experience of international EU-funded project SOLUTIONS shift focus a few legacy chemicals complex mixtures, identify relevant drivers toxic effects. Monitoring serves range purposes, control ecological status compliance specific uses, such as...
Two soils were amended three times with pig manure. The abundance of sulfonamide resistance genes was determined by quantitative PCR 2 months after each application. In both treated sulfadiazine-containing manure, the numbers copies sul1 and sul2 significantly increased compared to treatments antibiotic-free manure or a control accumulated repeated applications.
Following a request from EFSA, the Panel on Plant Protection Products and their Residues (PPR) developed an opinion state of art Toxicokinetic/Toxicodynamic (TKTD) models use in prospective environmental risk assessment (ERA) for pesticides aquatic organisms. TKTD are species- compound-specific can be used to predict (sub)lethal effects under untested (time-variable) exposure conditions. Three different types described, viz., (i) 'General Unified Threshold Survival' (GUTS), (ii) those based...
Abstract Aquatic ecosystems are affected by man-made pressures, often causing combined impacts. The analysis of the impacts chemical pollution is however commonly separate from that other pressures and their This evolved differences in data available for applied ecology vis-à-vis ecotoxicology, which field gradients laboratory toxicity tests, respectively. With this study, we demonstrate current approach impact assessment, consisting comparing measured concentrations to protective...
Abstract Acetamiprid is a pesticide active substance with insecticidal action whose approval was renewed by Commission Implementing Regulation (EU) 2018/113. In January 2022, the EFSA PPR Panel published statement following request from European to advise on human health or environment based new scientific evidence presented France during decision-making phase. July means of further mandate received Commission, requested provide advice if information and any other that has become available...
Difloxacin (DIF) belongs to the class of fluoroquinolone antibiotics that have been intensively used for treatment bacterial infections in veterinary and human medicine. The aim this field study was compare effect manure from DIF-treated pigs untreated on community structure resistance gene abundance bulk soil rhizosphere maize. A significant DIF composition revealed by denaturing gradient gel electrophoresis (DGGE) 16S rRNA fragments amplified total DNA. In few samples, quinolone genes qnrB...
Abstract The General Unified Threshold model for Survival (GUTS) integrates previously published toxicokinetic-toxicodynamic models and estimates survival with explicitly defined assumptions. Importantly, GUTS accounts time-variable exposure to the stressor. We performed three studies test ability of predict aquatic organisms across different pesticide patterns, time scales species. Firstly, using synthetic data, we identified experimental data requirements which allow estimation all...
In this study, a trait-based macroinvertebrate sensitivity modeling tool is presented that provides two main outcomes: (1) it constructs ranking and, subsequently, predictive trait model for each one of diverse set predefined Modes Action (MOAs) and (2) reveals data gaps restrictions, helping with the direction future research. Besides revealing taxonomic patterns species sensitivity, we find there was not genus, family, or class which most sensitive to all MOAs common test taxa were often...
The prospective aquatic environmental risk assessment (ERA) of pesticides is generally based on the comparison predicted concentrations in edge-of-field surface waters with regulatory acceptable derived from laboratory and/or model ecosystem experiments organisms. New improvements mechanistic effect modeling have allowed a better characterization ecological risks through incorporation biological trait information and landscape parameters to assess individual, population community-level...
Understanding factors driving the ecology of N cycling microbial communities is central importance for sustainable land use. In this study we report changes abundance denitrifiers, nitrifiers and nitrogen-fixing microorganisms (based on qPCR data selected functional genes) in response to different use intensity levels consequences potential turnover rates. We investigated grassland sites being comparable with respect soil type climatic conditions, which have been continuously treated many...
Abstract The present monitoring and assessment of water quality problems fails to characterize the likelihood that complex mixtures chemicals affect quality. European collaborative project SOLUTIONS suggests this can be estimated, amongst other methods, with improved component-based methods (CBMs). use CBMs is a well-established practice in WFD, as one lines evidence evaluate chemical pollution on per-chemical basis. However, currently limited pre-selection 45 approximately 300 monitored...
In the face of global climate change, where temperature fluctuations and frequency extreme weather events are increasing, it is needed to evaluate impact on ecological risk assessment chemicals. Current state-of-the-art mechanistic effect models, such as toxicokinetic–toxicodynamic (TK–TD) often do not explicitly consider a modulating factor. This study implemented in widely used modeling framework, General Unified Threshold model for Survival (GUTS). We tested using data from toxicokinetic...
A comprehensive understanding of chemical toxicity and temperature interaction is essential to improve ecological risk assessment under climate change. However, there only limited knowledge about the effect on chemicals. To fill this gap our mechanistic influence temperature, current study explored toxicokinetics chronic effects two insecticides, imidacloprid (IMI) flupyradifurone (FPF), Gammarus pulex at different temperatures (7-24 °C). In tests, organisms were exposed IMI or FPF for 2...
This article presents a framework to diagnose and predict the effects of chemicals, integrating 2 promising tools incorporate more ecology into ecological risk assessment, namely traits-based approaches modeling. Traits-based are used increasingly derive correlations between occurrence species traits chemical exposure from biological monitoring data. assessment can also be in diagnostic way, i.e., identify chemicals probably posing highest risks aquatic ecosystems. The describes how models...