- Genetic and phenotypic traits in livestock
- Meat and Animal Product Quality
- Genetic Mapping and Diversity in Plants and Animals
- Veterinary Equine Medical Research
- Muscle metabolism and nutrition
- Animal Genetics and Reproduction
- Genetics and Physical Performance
- Genetic diversity and population structure
- Adipose Tissue and Metabolism
- Animal Nutrition and Physiology
- Muscle Physiology and Disorders
- Animal Behavior and Welfare Studies
- Genetics and Plant Breeding
- Molecular Biology Techniques and Applications
- Effects of Environmental Stressors on Livestock
- Artificial Intelligence in Healthcare and Education
- melanin and skin pigmentation
- Insect Utilization and Effects
- Identification and Quantification in Food
- Prostate Cancer Diagnosis and Treatment
- Ruminant Nutrition and Digestive Physiology
- Neurological diseases and metabolism
- Pharmacological Effects and Assays
- Cancer-related molecular mechanisms research
- Peroxisome Proliferator-Activated Receptors
Universidade Estadual Paulista (Unesp)
2016-2025
Universidade de São Paulo
2023
Universidade Estadual de Maringá
2015
Hospital de Santa Maria
2010
Abstract Artificial intelligence (AI) has shown promise for diagnosing prostate cancer in biopsies. However, results have been limited to individual studies, lacking validation multinational settings. Competitions be accelerators medical imaging innovations, but their impact is hindered by lack of reproducibility and independent validation. With this mind, we organized the PANDA challenge—the largest histopathology competition date, joined 1,290 developers—to catalyze development...
Frequent measurements of body weight (BW) in livestock systems are very important because they allow assessing growth. However, real-time monitoring animal growth through traditional weighing scales is stressful for animals, costly and labor-intensive. Thus, the objectives this study were to: 1) assess predictive quality an automated computer vision system used to predict BW average daily gain (ADG) beef cattle; 2) compare different approaches, including Multiple Linear Regression (MLR),...
The Gleason score is the most important prognostic marker for prostate cancer patients, but it suffers from significant observer variability. Artificial intelligence (AI) systems based on deep learning can achieve pathologist-level performance at grading. However, of such degrade in presence artifacts, foreign tissue, or other anomalies. Pathologists integrating their expertise with feedback an AI system could result a synergy that outperforms both individual pathologist and system. Despite...
Abstract With the availability of high‐density SNP panels and establishment approaches for characterizing homozygosity heterozygosity sites, it is possible to access fine‐scale information regarding genomes, providing more than just comparisons different inbreeding coefficients. This first study that seeks such Mangalarga Marchador (MM) horse breed on a genomic scale. To this end, we aimed assess levels using coefficients, as well characterize homozygous heterozygous runs in population....
An inorganic/organic hybrid material with a triggering mechanism for specific drug delivery at the colon is synthesized.
Amorphous carbon nanoneedles-supported Co<sub>3</sub>O<sub>4</sub>nanoparticles, materials that have electrocatalytic activity for ORR and the ability to store charges, are synthesized with nanoreactors using Co(<sc>ii</sc>) ions cellulose nanowhiskers as precursor.
The DMRT3 gene is described as the main involved in determination of gait phenotypes horses, and allele A 22999655C>A single nucleotide polymorphisms (SNP) has been reported a causal variant this trait. In Mangalarga Marchador breed, which exhibits two patterns with well-defined characteristics, genotypes AA CA are associated marcha picada genotype CC batida. only related to gait. objective study was identify type control batida investigate SNPs genomic regions responsible for phenotype...
Introduction To determine the impact of early weaning combined with concentrate supplementation on skeletal muscle energy metabolism, we profiled gene co-expression networks in Bos indicus (Nellore) calves. Material and methods Longissimus thoracis biopsies were collected from eight calves per treatment (conventional weaning) at 120 205 days age (longitudinal sampling). All grazed Brachiaria decumbens pasture until days. Subsequently, weaned received a 1% body weight supplement (20% CP, 75%...
Abstract This study aimed to compare dry matter intake (DMI), feed efficiency, carcass traits, and meat quality between feedlot Bos indicus cattle with divergent residual (RFI). Ninety-six Nellore bulls (initial body weight 362.45 ± 25.6 kg, aged 24-26 months) underwent a 70-d efficiency test in group-pen system equipped individual gain monitoring. After classification into low (efficient) high (inefficient) RFI groups (-0.54 vs. 0.59 kg/d, respectively), the animals were slaughtered at...
Objective: According to data from Brazil's National Cancer Institute nearly 30% of the new patients who present with breast cancer have locally advanced disease. These are inoperable and tumor reduction is usually attempted chemotherapy. First-line anthracyclin-based neoadjuvant chemotherapy often effective; however, about fail date there no established second-line treatment. We studied concomitant use radiation therapy capecitabine in this setting, determine toxicity efficacy regimen as a...
The objective of this study was to estimate allele frequencies the g.98535683A>G:BTAU7 SNP in CAST gene different genetic groups beef cattle produced Brazil (Nellore and their crosses with Bos taurus), evaluate associations between polymorphism meat traits. Five hundred animals from six were genotyped phenotyped for shear force (SF), myofibrillar fragmentation index (MFI), rib eye area, backfat thickness, total lipids. Alleles A G detected all frequency higher than G. Significant association...
Proteomics has been widely used to study muscle biology and meat quality traits from different species including beef. Beef proteomics studies allow a better understanding of the biological processes related trait determination. This aimed decipher by means two-dimensional electrophoresis (2D-PAGE), mass spectrometry bioinformatics changes in post-mortem with focus on proteins differentially expressed Longissimus thoracis (LT) immunocastrated young heifers steers. Carcass traits, chemical...
This study aimed to evaluate population parameters and describe the genetic diversity of Quarter Horse breed (QH) in Brazil, reported for first time literature. The pedigree data comprised 131,716 animals representing total (TP), with records born between 1747 2008. reference (RP) last generation was applied this considering 47,861 2000 average interval 9.6 10.8 years TP RP, respectively. equivalent complete generations (EG) were 5.09 (TP) 6.24 (RP). inbreeding coefficient (F), relatedness...
Abstract Linkage disequilibrium (LD) plays an important role in genomic selection and mapping of quantitative trait loci (QTL). This study investigated the pattern LD effective population size ( N e ) Gir cattle selected for yearling weight. For this purpose, 173 animals with imputed genotypes (from 18 genotyped Illumina BovineHD BeadChip 155 Bovine LDv4 panel) were analysed. The was evaluated at distances 25–50 kb, 50–100 100–500 kb 0.5–1 Mb. estimated based on 5 past generations. r 2...
This study evaluated the effects of hanging carcass by Achilles tendon (AS) versus pelvic suspension (PS) on meat quality traits. Bos indicus carcasses two distinct biological types/sex categories comprised 10 young Brangus heifers and Nellore bulls which were finished in a feedlot. Half-carcasses each type/sex category randomly hung using (n = 20, AS) or PS) for 48 h. At boning, longissimus samples collected evaluation untrained consumers tenderness, liking flavor, juiciness overall...
Different selection goals in the Quarter Horse breed have led to formation of lines. These lines different skills such as working with cattle or running and differ morphology, physiology inbreeding. The aim this study was characterize linkage disequilibrium (LD, r2) cutting racing Horses bred Brazil using large-scale SNP genotyping. Additionally, effective population size (Ne) two populations (lines) determined, well their structure relationships. A total 428 (both sexes) (cutting: 68;...
A genome-wide association study for morphometric traits was conducted in 184 Quarter Horses, 120 from a racing population, and 64 cutting which were genotyped using the Illumina EquineSNP50 chip. Association analysis performed with 42,058 single-nucleotide polymorphisms (SNPs) (after quality control) Qxpak5 software. The following measured: weight (W), rump length (RL), body (BL). These are important best performance race events. For weight, three SNPs associated (P < .0001) found on...
Different selection objectives within the Quarter Horse breed led to formation of groups with distinct skills, including racing and cutting lines. With a smaller population size in Brazil, but great economic representativeness, line is characterized by animals that can reach high speeds over short distances period time. The destined for functional tests, exploring skills such as agility obedience. Although athletic performance horses likely be influenced large number genes, few genetic...