John G. Aversa

ORCID: 0000-0002-0430-6803
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About
Contact & Profiles
Research Areas
  • Colorectal Cancer Surgical Treatments
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Pancreatic and Hepatic Oncology Research
  • Neuroendocrine Tumor Research Advances
  • Gastrointestinal Tumor Research and Treatment
  • Gastric Cancer Management and Outcomes
  • Venous Thromboembolism Diagnosis and Management
  • Lung Cancer Research Studies
  • Enhanced Recovery After Surgery
  • Blood transfusion and management
  • Esophageal and GI Pathology
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Viral-associated cancers and disorders
  • Acute Ischemic Stroke Management
  • Trauma and Emergency Care Studies
  • Esophageal Cancer Research and Treatment
  • Colorectal Cancer Screening and Detection
  • Cardiovascular and Diving-Related Complications
  • Hemophilia Treatment and Research
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Vascular Tumors and Angiosarcomas
  • Cancer, Stress, Anesthesia, and Immune Response
  • Acute Myocardial Infarction Research
  • Abdominal Trauma and Injuries

National Institutes of Health
2019-2024

National Cancer Institute
2019-2024

Rush University Medical Center
2023

City of Hope
2023

Indiana University School of Medicine
2019-2022

Indiana University – Purdue University Indianapolis
2015-2022

Center for Cancer Research
2019-2021

Twitter (United States)
2021

University of Lübeck
2020

Indiana University
2015

Ampullary adenocarcinoma is a rare malignant neoplasm that arises within the duodenal ampullary complex. The role of adjuvant therapy (AT) in treatment has not been clearly defined.To determine if long-term survival after curative-intent resection may be improved by selection patients for AT directed histologic subtype.This multinational, retrospective cohort study was conducted at 12 institutions from April 1, 2000, to July 31, 2017, among 357 with resected, nonmetastatic receiving surgery...

10.1001/jamasurg.2019.1170 article EN JAMA Surgery 2019-05-29

Esophageal squamous cell carcinoma (ESCC) is the predominant histologic subtype of esophageal cancer worldwide. Measurements circulating inflammation‐related biomarkers may inform etiology or provide noninvasive signatures for early diagnosis. We therefore examined levels inflammation molecules associations with ESCC risk. Using a case–cohort study designed within Japan Public Health Center‐based Prospective Study, we measured baseline plasma 92 using multiplex assay in subcohort 410...

10.1002/ijc.32763 article EN International Journal of Cancer 2019-10-31

Abstract Background Li-Fraumeni syndrome is a cancer predisposition caused by germline TP53 tumor suppressor gene mutations, with no previous association pancreatic neuroendocrine tumors (PNETs). Here we present the first case of PNET associated syndrome. Case presentation This 43-year-old female who underwent laparoscopic distal pancreatectomy at age 39 for well-differentiated grade 2 cystic PNET. When patient was 41 years old, her seven-year-old daughter found to have an astrocytoma and...

10.1186/s12885-020-06723-6 article EN cc-by BMC Cancer 2020-03-30

The role of adjuvant chemotherapy in resected stage II colon cancer remains controversial. Treatment recommendations rely largely on the presence certain high-risk features for recurrence.

10.1097/dcr.0000000000002074 article EN Diseases of the Colon & Rectum 2021-12-13

Highlights•Characterization of extrahepatic biliary neuroendocrine tumors, EBNETs, including factors associated with survival.•Older age, lymph node metastases, and poorly/undifferentiated tumors were worse OS.•Patients EBNETs experienced abbreviated OS compared to patients small bowel or pancreas NETs, but improved when gallbladder NETs.AbstractBackgroundExtrahepatic (EBNETs) are rare. We aimed characterize survival.MethodsThe National Cancer Database was queried for from 2004 2016....

10.1016/j.heliyon.2024.e34714 article EN cc-by-nc-nd Heliyon 2024-07-23

Abstract Background Most gallbladder cancers are diagnosed after cholecystectomy for presumed benign disease, and nodal staging to inform subsequent treatment is therefore often lacking. We evaluated the association of lymphovascular invasion (LVI) with regional lymph node involvement in adenocarcinoma its impact on survival. Methods The National Cancer Database was queried identify patients resected available LVI status. Patients pT4 M1 disease were excluded. Univariable multivariable...

10.1002/jso.26160 article EN Journal of Surgical Oncology 2020-08-11

This cohort study examines national rates of neoadjuvant dual-agent chemotherapy and radiation followed by surgery in patients with locally advanced esophageal carcinoma after a randomized clinical trial demonstrated survival advantage.

10.1001/jamaoncol.2020.1065 article EN JAMA Oncology 2020-05-21
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