A5063762384- Prenatal Screening and Diagnostics
- Advanced MIMO Systems Optimization
- Millimeter-Wave Propagation and Modeling
- Antenna Design and Analysis
- Fetal and Pediatric Neurological Disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Genetic and Kidney Cyst Diseases
- Parvovirus B19 Infection Studies
- Renal and related cancers
- Genomic variations and chromosomal abnormalities
- Connexins and lens biology
- Vestibular and auditory disorders
- Image and Video Quality Assessment
- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Genetic Syndromes and Imprinting
- Connective tissue disorders research
- Maternal and fetal healthcare
- Advanced Image Fusion Techniques
- Liver Disease Diagnosis and Treatment
- Advanced Wireless Communication Techniques
- Advanced Glycation End Products research
- Healthcare and Venom Research
- Animal Behavior and Reproduction
- Olfactory and Sensory Function Studies
Guangzhou University of Chinese Medicine
2025
Leshan Normal University
2025
Integrated Chinese Medicine (China)
2025
Shenzhen Bao'an District People's Hospital
2024
Zhejiang Taizhou Hospital
2014-2024
Wenzhou Medical University
2014-2024
Chinese Academy of Forestry
2021-2024
Research Institute of Tropical Forestry
2021-2024
Chinese PLA General Hospital
2013-2023
Central Hospital of Zibo
2021-2022
ABSTRACT Semliki Forest virus (SFV) and Sindbis (SIN) are enveloped alphaviruses that enter cells via low-pH-triggered fusion in the endocytic pathway exit by budding from plasma membrane. Previous studies with cholesterol-depleted insect have shown SFV requires cholesterol cell membrane for both efficient of progeny virus. An mutant, srf-3 , shows absence due to a single point mutation E1 spike subunit, proline 226 serine. We here characterized role entry SIN, an alphavirus quite distantly...
Human guanylate-binding protein-1 (hGBP-1) is a large GTPase, similar in structure to the dynamins. Like many smaller GTPases of Ras/Rab family, it farnesylated, suggesting may dock into membranes and perhaps play role intracellular trafficking. To date, however, hGBP-1 has never been associated with specific compartment. Here we present evidence that can associate Golgi apparatus. Redistribution from cytosol was observed by immunofluorescence subcellular fractionation after aluminum...
Adaptation of D. radiodurans cells to extreme irradiation environments requires dynamic interactions between gene expression and metabolic regulatory networks, but studies typically address only a single layer regulation during the recovery period after irradiation. Dynamic transcriptome analysis using strand-specific RNA sequencing (ssRNA-seq), combined with LC-MS based metabolite analysis, allowed an estimate immediate pattern genes antioxidants in response Transcriptome dynamics were...
ABSTRACT All enveloped viruses must bud through a cellular membrane in order to acquire their lipid bilayer, but little is known about this important stage virus biogenesis. We have developed quantitative biochemical assay monitor the budding of Semliki Forest (SFV), an alphavirus that buds from plasma reaction requiring both viral spike proteins and nucleocapsid. The was based on cell surface biotinylation newly synthesized retrieval biotinylated virions using streptavidin-conjugated...
Hemophagocytic lymphohistiocytosis (HLH) is a rare severe clinical syndrome. HLH manifesting during pregnancy has been paid much attention in recent years. Despite the specificity of pregnancy-related HLH, there not any consensus regarding its treatment. According to previous study, corticosteroid/IVIG mainstream therapy; however, efficacy controversial. Etoposide an important agent HLH-94 regimen; nevertheless, use limited because possible toxicity fetus. Methods: In this we summarized 13...
Introduction Postoperative delirium (POD) is a common complication after hip fracture surgery in older patients. Esketamine may be beneficial alleviating the occurrence of POD. Our trial aim to investigate whether intravenous administration esketamine can improve POD patients undergoing for fracture. Methods and analysis This randomised controlled will conducted at Chengdu Integrated TCM & Western Medicine Hospital Chengdu, China. A total 260 scheduled under general anaesthesia randomly...
Cyberbullying victimization (CV) has been linked to numerous adverse psychological outcomes among adolescents. While previous research established associations between CV and negative including depression, diminished self-esteem, academic burnout, the potential protective mechanisms in these relationships remain underexplored. This longitudinal study investigated mediating role of mindfulness Chinese A sample 1,421 high school students participated this study. The participants were asked...
Our objective was to compare the clinical features of Metabolic dysfunction-associated steatotic liver disease (MASLD) /metabolic alcohol-related (MetALD)/metabolic associated fatty (MAFLD)/nonalcoholic (NAFLD) and relative risk analysis metabolic disorders. The National Health Nutrition Examination Survey for 2017-2018 cycle used screen participants. Multivariate-adjusted logistic regression models were applied explore difference in between NAFLD/MAFLD/MASLD/MetALD Among 1,862 eligible...
Stem segments of Acacia mangium and A. auriculiformis containing full axillary buds were used to study the effects reduced amounts main nitrogen source in growth media. This condition, referred as deficiency this article denoted -N, involved omission ammonium nitrate potassium from MS media, its impact on bud induction was assessed. The results show that media lacking nitrogen, rate, contamination browning stem length, leaf number induced varied depending different culture used. optimal...
Massive multiple input and output (MIMO) systems can increase the spectrum energy efficiency of existing cells, because this, massive MIMO has been considered as a potential technique for next generation wireless communication networks. Since thorough knowledge propagation channel is prerequisite reliable systems, channels are great current interest. However, few investigations have done on channels, especially angle properties. In this paper, based realistic measurement in typical stadium...
A couple with a proband child of GJB2 (encoding the gap junction protein connexin 26)-associated hearing impairment and previous pregnancy miscarriage sought for reproductive solution to bear healthy child. Our study aimed develop customized preconception-to-neonate care trajectory fulfill this clinical demand by integrating preimplantation genetic diagnosis (PGD), noninvasive prenatal testing (NIPT), (NIPD) into strategy. Auditory was carried out identify disease causative mutations. The...
Nutrition and health of northern white-cheeked gibbons (Nomascus leucogenys) are considered to be primarily influenced by the diversity their gastrointestinal tract (GIT) microbiota. However, precise composition, structure, role gibbon GIT microbiota remain unclear. Microbial communities from GITs Nanning (NN, n = 36) Beijing (BJ, 20) Zoos were examined through 16S rRNA sequencing. Gibbon's microbiomes contained bacteria 30 phyla, dominated human-associated microbial signatures: Firmicutes,...
During human pregnancy, placental trophectoderm cells release extracellular vesicles (EVs) into maternal circulation. Trophoblasts also give rise to cell-free DNA (cfDNA) in blood, and has been used for noninvasive prenatal screening chromosomal aneuploidy. We intended prove the existence of EVs (evDNA) compared evDNA with plasma cfDNA terms genome distribution, fragment length, possibility detecting genetic diseases. Maternal blood from 20 euploid pregnancies, 9 T21 3 T18 1 T13 2...
Meckel-Gruber syndrome type 3 is an autosomal recessive genetic defect caused by mutations in TMEM67 gene. In our previous study, we have identified a homozygous mutation Chinese family exhibiting clinical characteristics of MKS3, which provided ground for further PGD procedure. Here report the development and first application this MKS3 family. Molecular analysis protocol procedure was established using 50 single cells pre-clinical set-up. After whole genomic amplification multiple...