A5100346273- Endometriosis Research and Treatment
- Endometrial and Cervical Cancer Treatments
- Cervical Cancer and HPV Research
- Ectopic Pregnancy Diagnosis and Management
- Prenatal Screening and Diagnostics
- Glycosylation and Glycoproteins Research
- Liver Disease Diagnosis and Treatment
- Uterine Myomas and Treatments
- Genetic and Kidney Cyst Diseases
- Telomeres, Telomerase, and Senescence
- Monoclonal and Polyclonal Antibodies Research
- Reproductive System and Pregnancy
- Gynecological conditions and treatments
- Acute Ischemic Stroke Management
- Influenza Virus Research Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pleural and Pulmonary Diseases
- Nausea and vomiting management
- Epigenetics and DNA Methylation
- Reproductive tract infections research
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver physiology and pathology
- Genetic Syndromes and Imprinting
- Cancer, Lipids, and Metabolism
- Airway Management and Intubation Techniques
Shanxi Province Hospital of Traditional Chinese Medicine
2024
First Hospital of Shanxi Medical University
2024
Shanxi Medical University
2023-2024
Henan University of Traditional Chinese Medicine
2024
Qingdao University
2023-2024
Affiliated Hospital of Qingdao University
2023-2024
Peking University Third Hospital
2023
Peking University
2023
China Association for Science and Technology
2023
Chinese PLA General Hospital
2011-2022
To report the performance of massively parallel sequencing (MPS) based prenatal noninvasive fetal trisomy test on cell-free DNA from maternal plasma in a routine clinical setting China.The MPS-based was offered as screening for trisomies 21 and 18 to pregnant women 49 medical centers over 2 years. A total 11,263 participants were recruited performed 11,105 pregnancies. Fetal outcome data obtained after expected date confinement.One hundred ninety cases classified positive, including 143 47...
Abstract We assessed the prevalence characteristics of single and multiple high‐risk human papillomavirus (HR‐HPV) infections. A total 1783 women who underwent colposcopy cervical biopsy for abnormal ThinPrep Cytology Test and/or HR‐HPV subtype genotyping results were enrolled in study. Among participants, 770 diagnosed with cervicitis, 395 intraepithelial neoplasia grade 1 (CIN1), 542 CIN2‐3, 76 squamous cell carcinoma (SCC), infection rates 75.8%, 85.8%, 95.9%, 88.4%, respectively. The...
Abstract Epidemiological studies indicate an inverse correlation between the prevalence of so-called western diseases, such as obesity and metabolic syndrome, exposure to helminths. Obesity, a key risk factor for many chronic health problems, is rising globally accompanied by low-grade inflammation in adipose tissues. The precise mechanism which helminths modulate syndrome not fully understood. We infected high fat diet (HFD)-induced obese mice with intestinal nematode parasite...
Endometriosis is a complex and enigmatic disease that arises from the interplay among multiple genetic environmental factors. The defining feature of endometriosis deposition growth endometrial tissues at sites outside uterine cavity. Studies to date have established heritable but not addressed causal variants for this disease. Here, we conducted whole-exome sequencing comprehensively search somatic mutations in both eutopic ectopic endometrium 16 patients five normal control using laser...
Background: Lenvatinib combined with a PD-1 inhibitor has obtained satisfactory antitumor effect in several solid tumors. However, the efficacy and tumor response of lenvatinib advanced intrahepatic cholangiocarcinoma still need further exploration. Methods: This is single-arm study for assessment tolerability patients who had chemotherapy failure. Efficacy was evaluated based on Response Evaluation Criteria Solid Tumors RECIST Version 1.1 (RECIST 1.1). Results: A total 40 were enrolled...
The triglyceride-glucose (TyG) index, a simple measure of insulin resistance, is associated with intracranial atherosclerosis (ICAS) and stroke. In hypertensive populations, this association may be pronounced. aim was to investigate the relationship between TyG symptomatic (sICAS) recurrence risk in ischemic stroke patients hypertension.This prospective, multicenter cohort study included acute minor preadmission diagnosis hypertension from September 2019 November 2021 3-month follow-up....
Background Direct and indirect evidences have suggested that angiogenesis is a prerequisite for the development of endometriosis. Aiming at offering experimental anti-angiogenesis therapy, we transplanted eutopic endometrium from patient with endometriosis into severe combined immunodeficiency disease (SCID) mice, to evaluate effect endostatin on growth established lesions in SCID mice model. Methods Eutopic women was mice. The were randomized treatment (n=10) control groups (n=10). Two...
ARHI is a maternally imprinted tumor suppressor gene that responsible for initiating programmed cell death and inhibiting cancer growth. However, the influence of on epithelial ovarian underlying mechanisms behind how regulates cells still require further studies.Epithelial TOV112D ES-2 were used in this vitro study. Cell proliferation, apoptosis, autophagy activities compared transfected with vectors or control vectors. Bcl-2 siRNA was into to investigate roles played regulating apoptosis...
Bariatric surgery is one of the most effective ways to treat morbid obesity, and postoperative nausea vomiting (PONV) common complications after bariatric surgery. At present, mechanism high incidence PONV weight-loss has not been clearly explained, this study aims investigate effect surgical position on in patients undergoing
Failure in early diagnosis and ineffective treatment are the major causes of ovarian cancer mortality. Hyaluronan its receptor, cluster differentiation (CD)44, have been considered to be valid targets for treating cancer. The anti-CD44 monoclonal antibody IM7 is effective cancer; however, toxicity should not ignored. present study has developed a new drug carrier system composed chitosan nano-particles coated with polylactic acid (PLA) improve efficacy reduce toxicity. An ionic crosslinking...
Abstract Background Radiofrequency ablation (RFA) is considered as a convenient treatment with mild damage in treating recurrent hepatocellular carcinoma (RHCC). However, for patients high risk of progression after RFA still needs new strategies to decrease the repeat recurrence. Methods A total 460 RHCC within Milan criteria four institutions were enrolled. 174 pairs enrolled propensity score matching (PSM). Overall survival (OS) and tumor-free (TFS) compared between two groups....