A5101640863- Primary Care and Health Outcomes
- Chronic Disease Management Strategies
- Diabetes Management and Education
- Healthcare Policy and Management
- Obesity and Health Practices
- Mobile Health and mHealth Applications
- Health Promotion and Cardiovascular Prevention
- Global Health Workforce Issues
- Clinical practice guidelines implementation
- Diabetes and associated disorders
- Health Literacy and Information Accessibility
- Migration, Health and Trauma
- Diabetes Management and Research
- Health Systems, Economic Evaluations, Quality of Life
- Pancreatic function and diabetes
- Interprofessional Education and Collaboration
- Healthcare Systems and Technology
- Obesity, Physical Activity, Diet
- Health disparities and outcomes
- Health Policy Implementation Science
- Birth, Development, and Health
- Mental Health and Patient Involvement
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Child and Adolescent Health
- Health, psychology, and well-being
UNSW Sydney
2016-2025
The University of Queensland
2015-2024
Queensland Children’s Hospital
2015-2024
The University of Sydney
1994-2024
Primary Health Care
2012-2024
Neuroscience Research Australia
2024
Murdoch Children's Research Institute
2024
Royal Children's Hospital
2024
Children's Hospital at Westmead
2024
Sydney Children's Hospital
2024
An adverse prenatal environment may induce long-term metabolic consequences, in particular obesity and insulin resistance. Although the mechanisms are unclear, this programming has generally been considered an irreversible change developmental trajectory. Adult offspring of rats subjected to undernutrition during pregnancy develop obesity, hyperinsulinemia, hyperleptinemia, especially presence a high-fat diet. Reduced locomotor activity hyperphagia contribute increased fat mass. Using model...
We aimed to perform an observational study of age at loss independent ambulation (LoA) and side-effect profiles associated with different glucocorticoid corticosteroid (GC) regimens in Duchenne muscular dystrophy (DMD).We studied 340 participants the Cooperative International Neuromuscular Research Group Natural History Study (CINRG-DNHS). LoA was defined as continuous wheelchair use. Effects prednisone or prednisolone (PRED)/deflazacort (DFZ), administration frequency, dose were analyzed by...
Starvation causes a rapid reduction in thyroid hormone levels rodents. This adaptive response is caused by thyrotropin-releasing (TRH) expression that can be reversed the administration of leptin. Here we examined hypothalamic signaling pathways engaged leptin to upregulate TRH gene expression. As assessed leptin-induced suppressor cytokine signaling-3 (SOCS-3) fasted rats, neurons paraventricular nucleus are activated directly To greater degree, they also contain melanocortin-4 receptors...
Abstract Background With increasing rates of chronic disease associated with lifestyle behavioural risk factors, there is urgent need for intervention strategies in primary health care. Currently a gap the knowledge factors that influence delivery preventive by General Practitioners (GPs) around interventions smoking, nutrition, alcohol consumption and physical activity (SNAP). This qualitative study explores factor screening management GPs within 45–49 year old check consultation. The aims...
General practice can provide good quality care for a range of high-prevalence chronic diseases, at the same time providing continuity and management comorbidity. Although patients with disease is improving in general practice, about half patient does not meet optimal standards. Factors contributing to gap between current include method financing, availability other disciplines participate team care, limited engagement self-management education, lack information decision support systems....
Objectives: To review the effectiveness of chronic disease management interventions for physical health problems in primary care setting, and to identify policy options implementing successful Australian care. Methods: We conducted a systematic with qualitative data synthesis, using Chronic Care Model as framework analysis between January 1990 February 2006. Interventions were classified according which elements addressed: community resources, organisation, self-management support, delivery...
An adverse prenatal environment may induce long-term metabolic consequences, in particular obesity, hyperleptinemia, insulin resistance, and type 2 diabetes. Although the mechanisms are unclear, this "programming" has generally been considered an irreversible change developmental trajectory. Adult offspring of rats subjected to undernutrition (UN) during pregnancy develop hyperinsulinemia, especially presence a high-fat diet. Using model maternal UN, we have recently shown that neonatal...
Limited evidence exists regarding the relationship between health literacy and health-related quality of life (HRQoL) in Australian patients from primary care. The objective this study was to investigate impact on HRQoL a large sample without known vascular disease or diabetes examine whether difference low high groups clinically significant.This cross-sectional baseline data cluster randomised trial. included 739 30 general practices across four states conducted 2012 2013 using standard...
Weight gained in young adulthood often persists throughout later life with associated chronic disease risk. Despite this, current population prevention strategies are not specifically designed for adults.We and assessed the efficacy of an mHealth program, TXT2BFiT, preventing excess weight gain improving dietary physical activity behaviors adults at increased risk obesity unhealthy lifestyle choices.A two-arm, parallel-group randomized controlled trial was conducted. Subjects analyzing...
Ongoing care for chronic conditions such as diabetes is best provided by a range of health professionals working together. There are challenges in achieving this where collaboration crosses organisational and sector boundaries. The aim article to explore the influence power dynamics trust on between involved management their impact patient experiences. A qualitative case study conducted rural city Australia. Forty five service providers from nineteen organisations (including fee-for-service...
<h3>Objectives</h3> To quantify contemporary differences in cardiovascular disease (CVD) risk factor assessment and management between women men Australian primary healthcare services. <h3>Methods</h3> Records of routinely attending patients were sampled from 60 services 2012 for the Treatment Cardiovascular Risk using Electronic Decision Support study. Multivariable logistic regression models used to compare rate CVD recommended medication prescriptions, by gender. <h3>Results</h3> Of 53...
Background— Despite effective treatments to reduce cardiovascular disease risk, their translation into practice is limited. Methods and Results— Using a parallel arm cluster-randomized controlled trial in 60 Australian primary healthcare centers, we tested whether multifaceted quality improvement intervention comprising computerized decision support, audit/feedback tools, staff training improved (1) guideline-indicated risk factor measurements (2) medications for those at high risk. Centers...
The increased prevalence of diabetes and its significant impact on use health care services, particularly hospitals, is a concern for planners. This paper explores the risk factors all-cause hospitalisation excess due to in large sample older Australians. study population was 263,482 participants 45 Up Study. data assessed were linked records hospital admissions 12 months following completion baseline questionnaire. All cause ambulatory sensitive admission rates length stay examined....
The unprecedented rise in obesity among young adults, who have limited interaction with health services, has not been successfully abated.The objective of this study was to assess the maintenance outcomes a 12-week mHealth intervention on prevention weight gain adults and lifestyle behaviors at 9 months from baseline.A two-arm, parallel, randomized controlled trial (RCT) subjects allocated or control 1:1 conducted community setting Greater Sydney, Australia. From November 2012 July 2014, 18-...
Abstract Objective This study was aimed to assess the perceived fear of COVID-19 and its associated factors among older adults in Bangladesh. Methods cross-sectional conducted October 2020 1032 Bangladeshi aged ≥60 years. A semi-structured questionnaire used collect information on participants’ characteristics related information. Perceived measured using seven-item Fear Scale (FCV-19S), where cumulative score ranged from 7 35. Multiple linear regression performed identify with COVID-19....
<h3>Importance</h3> The quality of routine care for children is rarely assessed, and then usually in single settings or clinical conditions. <h3>Objective</h3> To estimate the health Australia inpatient ambulatory settings. <h3>Design, Setting, Participants</h3> Multistage stratified sample with medical record review to assess adherence indicators extracted from practice guidelines 17 common, high-burden conditions (noncommunicable [n = 5], mental 4], acute infection 7], injury 1]), such as...
BackgroundGenomic sequencing technology allows for identification of reproductive couples with an increased chance, as compared that in the general population, having a child autosomal recessive or X-linked genetic condition.MethodsWe investigated feasibility, acceptability, and outcomes nationwide, couple-based carrier screening program Australia part Mackenzie's Mission project. Health care providers offered to persons before pregnancy early pregnancy. The results obtained from testing at...