A5109353263- Cancer-related cognitive impairment studies
- Family Support in Illness
- Dementia and Cognitive Impairment Research
- Cancer survivorship and care
- Palliative Care and End-of-Life Issues
- Glioma Diagnosis and Treatment
- Brain Metastases and Treatment
- Tryptophan and brain disorders
- Family Caregiving in Mental Illness
- Family and Disability Support Research
- Intergenerational Family Dynamics and Caregiving
- Empathy and Medical Education
- Intensive Care Unit Cognitive Disorders
- Meningioma and schwannoma management
- Muscle Physiology and Disorders
- COVID-19 and Mental Health
- Head and Neck Surgical Oncology
- Cancer, Stress, Anesthesia, and Immune Response
- Privacy, Security, and Data Protection
- Technology Adoption and User Behaviour
- Digital Mental Health Interventions
- Digital Marketing and Social Media
- Schizophrenia research and treatment
- Patient-Provider Communication in Healthcare
- Diabetes Management and Research
AdventHealth Orlando
2024
University of Pittsburgh
2013-2023
Islamic Azad University of Najafabad
2021
The Sherwood Institute
2021
Berman Group (Czechia)
2021
University of Leeds
2018
Virginia Commonwealth University
2014
Neurological Surgery
2014
West Virginia University
2003
We aimed to perform an observational study of age at loss independent ambulation (LoA) and side-effect profiles associated with different glucocorticoid corticosteroid (GC) regimens in Duchenne muscular dystrophy (DMD).We studied 340 participants the Cooperative International Neuromuscular Research Group Natural History Study (CINRG-DNHS). LoA was defined as continuous wheelchair use. Effects prednisone or prednisolone (PRED)/deflazacort (DFZ), administration frequency, dose were analyzed by...
BACKGROUND Glioblastoma multiforme (GBM) is associated with a poor prognosis, and patients rely heavily on family caregivers for physical emotional support. The capability mental health of may influence their ability to provide care affect patient outcomes. objective the current study was investigate whether caregivers' anxiety, depressive symptoms, burden, mastery influenced survival in sample newly diagnosed GBM. METHODS Baseline data from caregiver‐patient dyads participating longitudinal...
Abstract There is a growing literature on the effects of cancer caregiving well‐being informal family caregivers. However, there has been little longitudinal research caregivers patients with complex, rapidly‐changing disease primary malignant brain tumor. Objective Our objective was to model relationships between caregiver burden, social support, and distress within Methods Caregiver participants were recruited from neuro‐oncology clinic. questionnaire data, including sociodemographics,...
Background Stress biomarkers are documented in neuro-oncology family caregivers, although those reported to date not routinely assessed primary care, limiting their clinical utility. Objective This secondary analysis explored the impact of an 8-week, nurse-caregiver collaborative problem-solving intervention on a clinically relevant biomarker (C-reactive protein [CRP]) adult caregivers. Interventions/Methods As part randomized trial evaluate effectiveness intervention, CRP levels were...
Primary brain tumors (PBTs) are rare but have a great impact on both patient and family caregiver wellbeing. Supporting caregivers can help them to continue their caregiving activities maintain the patients' best possible level of quality life. Efforts improve PBT wellbeing should take into account country- or culture-specific differences in care issues supportive needs serve larger groups. We aimed explore caregivers' satisfaction with current provision, as well thoughts monitoring...
Skull base tumors comprise many common benign brain tumors. Treatment has advanced, allowing survivors to return work. However, literature is limited about the neuropsychological status of these patients prior treatment. Literature pertaining relationship between functioning and occupational ability surgical intervention even more limited. The purpose this analysis was evaluate impact function on work productivity in persons with skull resection.Neuropsychological were assessed adults newly...
OBJECTIVE: To report clinical findings resulting from a switch branded to generic clozapine. METHODS: Twenty patients diagnosed with schizophrenia were followed in this naturalistic outpatient study. The Positive and Negative Syndrome Scale (PANSS), Beck Anxiety Inventory (BAI), Abnormal Involuntary Movement Scale, the Disorder Assessment used assess differences status of before after switching Clozaril clozapine (Mylan Pharmaceuticals). Results analyzed by means paired t-test calculation...
Glioblastoma multiforme (GBM) is an aggressive brain tumor. Patients commonly rely on family caregivers for physical and emotional support. We previously demonstrated that caregiver mastery measured shortly after diagnosis was predictive of GBM patient survival, corrected known predictors survival (n = 88).The aims this study were to verify the contribution investigate added value over other predict 15-month survival.Data collected a longitudinal (NCT02058745) used. Multivariable Cox...
ABSTRACT BACKGROUND: Negative physical health results from the emotional stress of providing care to a family member with primary malignant brain tumor; however, downstream effects on caregivers' healthcare utilization (HCU) are unknown. This analysis examined associations between and markers HCU during 6 months after patients' diagnoses. METHODS: Caregivers' self-report data longitudinal study 116 neuro-oncology caregivers were analyzed. Healthcare was operationalized as number prescription...
Tight glycemic control is essential for optimal outcomes after coronary artery bypass graft (CABG) surgery, regardless of pre-operative diabetes status. The ideal timing transitioning from intravenous (IV) to subcutaneous (SC) insulin remains unclear. This study addresses this knowledge gap by comparing the effects early transition (postoperative day 1, POD1) versus delayed on and patient CABG surgery.
Primary brain tumors (PBTs) are rare but have a great impact on both patient and family caregiver wellbeing. Supporting caregivers can help them to continue their caregiving activities maintain the patients’ best possible level of quality life. Efforts improve PBT wellbeing should take into account country- or culture-specific differences in care issues supportive needs serve larger groups. To explore caregivers’ satisfaction with current provision, as well thoughts monitoring paper-based...
The informal care demands of brain tumour patients include various issues associated with neurological and cognitive symptoms. Caregiver needs questionnaires developed for cancer populations do not these disease-specific Therefore, we have the neuro-oncology Needs Screen (CNS) evaluated its psychometric properties. In-depth qualitative interviews caregivers were used to generate items, which reviewed by experts add or collapse items as necessary. resulting 32-item instrument was tested in a...
Family caregivers (CG’s) of patients with primary malignant brain tumors (PMBT) face psychological and physical health challenges as a consequence providing this level care. These CG’s are high-risk for poor outcomes they manage both cancer-related neurodegenerative-related issues. SmartCare© (R01 NR013170) is 3-arm randomized-controlled trial testing an Internet- telephone-based caregiver support intervention. This analysis presents the most common care issues worked on by in intervention...
Family caregivers are vital in the care of persons with a primary malignant brain tumor (PMBT) and also report high levels psychological distress. The impact distress on caregivers' physical health has not been explored neuro-oncology. aims study were to determine profiles proinflammatory cytokines (IL-6 IL-1ra) over time PMBT identify effect their cytokine levels. After institutional review board approval, sociodemographic data, measures (depressive symptoms, anxiety, caregiver burden)...
It has been shown that family caregivers of persons with a primary malignant brain tumor (PMBT) report high levels depressive symptoms and burden caregivers’ emotional health is closely linked to the patient’s overall neuropsychological status. However, it not clear which domains function place at highest risk for poor health, severely limits interventions improve caregiver health. As part an ongoing NINR longitudinal trial (R01NR013170), 113 dyads newly (within two months) diagnosed PMBT...
Cognitive impairment is one of the most disabling symptoms for individuals with PBMTs and has been identified as a major source psychological distress by caregivers. Domain specific data regarding cognitive dysfunction following surgery primarily from research conducted prior to advent current standards care. The aims this analysis were identify domains function affected in post-operative/treatment phases examine predictors poor performance those using selected battery neuropsychological...
Family caregivers of persons with a primary malignant brain tumor have reported extremely high levels emotional distress compared to similarly aged adults who do not identify as or other health conditions. Despite several decades research linking family caregiver activation psycho-biological stress pathways, little has been done in cancer and almost none neuro-oncology. The purpose this analysis was evaluate the relationship between C-reactive protein (CRP), that is closely linked poor...
2095 Background: Primary Brain Tumor (PBT) and its treatment result in reduced cognitive function which significantly interferes with work, personal, social activities. Depression is also a clinically significant problem patients PBT at diagnosis, during post-treatment. Recent research non-cancer mild-cognitive impairment has found strong associations between depression; however this association been little researched patients. The goal of the present study was to explore potential...