A5056307563- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Cardiac Arrest and Resuscitation
- Cerebrovascular and Carotid Artery Diseases
- Mechanical Circulatory Support Devices
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Ischemia and Reperfusion
- Health Promotion and Cardiovascular Prevention
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiac Valve Diseases and Treatments
- Cardiovascular Health and Risk Factors
- Ultrasound Imaging and Elastography
- Venous Thromboembolism Diagnosis and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiac Arrhythmias and Treatments
- Cardiac Health and Mental Health
- Cardiovascular Function and Risk Factors
- Photoacoustic and Ultrasonic Imaging
- Global Public Health Policies and Epidemiology
- Cardiovascular Health and Disease Prevention
- Ultrasonics and Acoustic Wave Propagation
- Medical Imaging and Analysis
- Statistical Methods in Epidemiology
Medisch Centrum Haaglanden
2009-2024
Amsterdam University Medical Centers
2021-2022
Leiden University Medical Center
2002-2017
Haga Hospital
2013
Leiden University
1984-2005
Amsterdam UMC Location University of Amsterdam
2003
Cardiovascular Research Foundation
2003
Ischemic heart disease is a major cause of out-of-hospital cardiac arrest. The role immediate coronary angiography and percutaneous intervention (PCI) in the treatment patients who have been successfully resuscitated after arrest absence ST-segment elevation myocardial infarction (STEMI) remains uncertain.
Background— Long coronary lesions treated with stents have a poor outcome. This study compared the 6-month outcome of stent implantation for long in patients randomized to intravascular ultrasound (IVUS; n=73) or angiographic guidance (n=71). Methods and Results— Stenoses >20 mm length reference diameter that permitted ≥3 were eligible. Primary end points minimal lumen (MLD) combined point death, myocardial infarction, target-lesion revascularization (TLR). Baseline clinical data...
Acute hemodynamic effects of cardiac resynchronization therapy (CRT) were reported previously, but detailed invasive studies showing consequences long-term CRT are not available.We studied 22 patients scheduled for implantation a device based on conventional criteria (New York Heart Association class III or IV, left ventricular [LV] ejection fraction <35%, bundle-branch block, and QRS duration >120 ms). During diagnostic catheterization before CRT, we acquired pressure-volume loops using...
<h3>Importance</h3> Ischemic heart disease is a common cause of cardiac arrest. However, randomized data on long-term clinical outcomes immediate coronary angiography and percutaneous intervention (PCI) in patients successfully resuscitated from arrest the absence ST segment elevation myocardial infarction (STEMI) are lacking. <h3>Objective</h3> To determine whether improves at 1 year after without signs STEMI, compared with delayed strategy. <h3>Design, Setting, Participants</h3> A...
To evaluate the clinical outcomes of sirolimus-eluting stent (SES) versus bare metal (BMS) implantation in patients with ST-segment elevation myocardial infarction (STEMI) at long-term follow-up.After five years, 310 STEMI randomly assigned to either SES or BMS, were compared. Survival rates comparable between groups (SES 94.3% vs. BMS 92.8%, p=0.57), as reinfarction (10.6% 13.7%, p=0.40), freedom death/re-MI (84.4% 79.8%, p=0.29) and target vessel failure (14.9% 21.7%, p=0.11). Likewise,...
Importance Several randomized clinical trials (RCTs) assessed the effect of immediate vs delayed coronary angiography in patients with out-of-hospital cardiac arrest (OHCA) without ST-segment elevations and found no difference short-term survival. However, association these strategies long-term outcomes identification patient subgroups that might benefit from tailored approaches remain unclear. Objective To compare or selective treatment for OHCA ST elevation on 1-year survival, identify may...
The percutaneous treatment of coronary bifurcation lesions remains hampered by suboptimal results, mainly in the side branch (SB), even with use drug-eluting stents. Dedicated stents could provide an attractive alternative to improve early outcomes and reduce SB restenosis. We aimed assess a prospective single-arm multicentre registry, safety effectiveness at 6-month clinical follow-up Tryton dedicated (SB) stent.In this international patients underwent stenting technique using stent,...
This paper describes a new approach to the automated segmentation of X-ray left ventricular (LV) angiograms, based on active appearance models (AAMs) and dynamic programming. A coupling shape texture information between end-diastolic (ED) end-systolic (ES) frame was achieved by constructing multiview AAM. Over-constraining model compensated for employing programming, integrating both intensity motion features in cost function. Two applications are compared: semi-automatic method with manual...
Gender and complete revascularisation are known to affect mortality. The objective of this study was analyse a gender difference in mortality with respect for multivessel disease after primary percutaneous coronary intervention (PPCI) ST-elevation myocardial infarction (STEMI) patients.In prospective consecutive cohort 1472 patients presenting STEMI PPCI, between January 2006 2010, 832 were analysed. outcome long-term mortality.Median follow-up 3.3 ± 1.2 years. Complete performed less...
Abstract Aims ST-depression and T-wave inversion are frequently present on the post-resuscitation electrocardiogram (ECG). However, prognostic value of ischaemic ECG patterns is unknown. Methods results In this post-hoc subgroup analysis Coronary Angiography after Cardiac arrest (COACT) trial, first in-hospital in out-of-hospital cardiac patients with a shockable rhythm was analysed for patterns. Ischaemia defined as ≥0.1 mV, ≥2 contiguous leads, or both. The primary endpoint 90-day...
The automated segmentation of lumen, vessel and stent boundaries in intravascular ultrasound (IMS) images will reduce the required analysis time subjectivity commonly used manual tracing procedure while three-dimensional reconstruction permits an advanced assessment morphology. We describe a knowledge model guided system for (semi-) automatic contour detection these borders. different steps complete IVUS pullback sequence are carried out such, that components assist each other. assists both...
BackgroundThe effect of immediate coronary angiography and percutaneous intervention (PCI) in patients who are successfully resuscitated after cardiac arrest the absence ST-segment elevation myocardial infarction (STEMI) on left ventricular function is currently unknown.MethodsThis prespecified sub-study a multicentre trial evaluated 552 patients, from out-of-hospital without signs STEMI. Patients were randomized to either undergo or delayed angiography, neurologic recovery. All underwent...
Acute myocardial infarction during substitution with recombinant factor VIII concentrate in a patient mild haemophilia A -
To evaluate the results of long Micro Stent II (MS-XL) implantations, 119 MS-XLs were implanted in 102 patients (age, 62.83 years). Nineteen stents (16%) saphenous vein grafts; 100 (84%) native coronary arteries. Twenty-five (25%) treated because acute myocardial infarction (AMI); 30 (29%) unstable angina or class IV, and 47 (46%) stable angina. Eighty-six de novo lesions 16 restenotic treated. Indications for stent implantation include elective, 61 (60%); suboptimal balloon angioplasty...