Emilija Manojlović-Gačić

ORCID: 0000-0002-0923-4212
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About
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Research Areas
  • Pituitary Gland Disorders and Treatments
  • Glioma Diagnosis and Treatment
  • Neuroendocrine Tumor Research Advances
  • Growth Hormone and Insulin-like Growth Factors
  • Neuroblastoma Research and Treatments
  • Meningioma and schwannoma management
  • Adrenal and Paraganglionic Tumors
  • Vascular Malformations Diagnosis and Treatment
  • Cancer-related Molecular Pathways
  • Childhood Cancer Survivors' Quality of Life
  • Long-Term Effects of COVID-19
  • Peripheral Neuropathies and Disorders
  • Myasthenia Gravis and Thymoma
  • Skin Diseases and Diabetes
  • Cancer, Hypoxia, and Metabolism
  • Ocular Oncology and Treatments
  • Sarcoma Diagnosis and Treatment
  • Systemic Sclerosis and Related Diseases
  • Coronary Artery Anomalies
  • Genetics and Neurodevelopmental Disorders
  • Cerebrospinal fluid and hydrocephalus
  • Tuberous Sclerosis Complex Research
  • Genetic and Kidney Cyst Diseases
  • Histiocytic Disorders and Treatments
  • IgG4-Related and Inflammatory Diseases

University of Belgrade
2015-2025

Institut za Reumatologiju
2022

University of Belgrade – Faculty of Medicine
2022

Institute of Physics Belgrade
2022

Grade Medical (Czechia)
2010

Abstract Context Aggressive pituitary tumors (APTs) are characterized by unusually rapid growth and lack of response to standard treatment. About 1% 2% develop metastases being classified as carcinomas (PCs). For unknown reasons, the corticotroph overrepresented among APTs PCs. Mutations in alpha thalassemia/mental retardation syndrome X-linked (ATRX) gene, regulating chromatin remodeling telomere maintenance, have been implicated development several cancer types, including neuroendocrine...

10.1210/clinem/dgaa749 article EN cc-by The Journal of Clinical Endocrinology & Metabolism 2020-10-27

Introduction. Plurihormonal pituitary neuroendocrine tumours (PitNET)/adenomas are composed of monomorphous cell populations expressing anterior transcription factors and/or hormones belonging to more than one lineage. Studies dedicated plurihormonal rare and quite heterogenous with their results, bearing in mind changes diagnostic criteria inconsistent use antibodies for the immunohistochemical panel. Material Methods. We retrospectively analysed all patients surgically treated PitNETs from...

10.1177/10668969231183712 article EN International Journal of Surgical Pathology 2023-07-12

Pituitary xanthogranulomatomas (XG) are a rare pathological entity caused by accumulation of lipid laden macrophages and reactive granuloma formation usually triggered cystic fluid leakage or hemorrhage. Our aim was to compare clinical characteristics presenting features patients with secondary etiology XG those no identifiable founding lesion (primary -"pure" XG) in order gain new insights into this pituitary pathology. In retrospective review 714 operated for sellar masses, at tertiary...

10.1507/endocrj.ej23-0398 article EN cc-by-nc-nd Endocrine Journal 2024-01-01

Actinic keratosis (AK) and Bowen's disease (squamous cell carcinoma in situ, SCCIS) are pre-invasive stages the development of squamous (SCC).Immunohistochemical study cyclin D1, E, p16(INK4a) p21(Cip1) (/Waf1) AK (53 cases), SCCIS (16 cases) SCC (40 relation to type lesion prognostic parameters (grade, diameter thickness).Diffuse D1 distribution was more frequent than (p = 0.03) similar pattern observed for . For central dominated compared with 0.001) 0.03). displayed suprabasal frequently...

10.1111/cup.12623 article EN Journal of Cutaneous Pathology 2015-09-09

To analyze metabolic parameters, body composition (BC), and bone mineral density (BMD) in childhood-onset GH deficiency (COGHD) patients during the transition period (TP).Single- center, retrospective study was performed on 170 consecutive COGHD (age 19.2 ± 2.0 years, range 16-25) transferred after growth completion from two pediatric clinics to adult endocrine unit. Two separate analyses were performed: (i) cross-sectional analysis of hormonal status, BC, BMD at first evaluation transfer...

10.1530/ec-21-0274 article EN Endocrine Connections 2021-07-14

Hematological neoplastic mass lesions of the sellar region are rare. We identified five cases hematological malignancy with first presentation in from our departmental database 1,405 patients (0.36%) diagnosed over 17-year period (2005-2021). All were females (mean age 55.2 ± 3.4 years). One patient had multiple myeloma (MM), one acute myeloid leukemia (AML), while three other lymphoma (intravascular (IVL, n = 1) or non-Hodgkin's (NHL, 2). Most presented ophthalmoplegia, and diabetes...

10.1507/endocrj.ej21-0790 article EN Endocrine Journal 2022-01-01

We report the case of an orbital optic nerve gangliogoma in a 55-year-old woman with neurofibromatosis type 1 (NF1). Clinical course neuroimaging findings, pathology, and treatment options gangliogloma are discussed contrasted pilocytic astrocytomas nerve, much more frequent visual pathway neoplasm NF1 patients.

10.1097/wno.0b013e318267ff55 article EN Journal of Neuro-Ophthalmology 2012-09-07

Background. Cavernous hemangioma is a frequent and the most common, primary, benign tumor of orbit in adults. It typically single unilateral, considered not to recur after having been completely excised. Multiple orbital cavernous hemangiomas without signs hemangiomatosis are rare. may complete excision exist with concurrent systemic tumors. Tumor recurrence supposed develop from vasculature that present already response proliferate stimulus. Case report. A 39-year old female painless...

10.2298/vsp1006507n article EN cc-by-sa Vojnosanitetski pregled 2010-01-01

Introduction: 18F-deoxy-glucose positron emission tomography combined with computed (18F-FDG PET/CT) is routinely used in the detection of malignant disease based on property cells to fuel their growth and replication by increased glucose uptake. Malignant lesions are rare sellar region, while pituitary adenomas most common pathology. These benign neoplasms insidious onset low proliferation activity, therefore only exceptionally detected 18F-FDG PET/CT. Studies that compare biology...

10.5603/ep.2017.0027 article EN cc-by-nc-nd Endokrynologia Polska 2017-06-22
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