A5085716872- Mental Health and Psychiatry
- Schizophrenia research and treatment
- Psychosomatic Disorders and Their Treatments
- Eating Disorders and Behaviors
- COVID-19 and Mental Health
- Tryptophan and brain disorders
- Healthcare Systems and Public Health
- Mental Health Research Topics
- Neuroinflammation and Neurodegeneration Mechanisms
- Mental Health Treatment and Access
- Personality Disorders and Psychopathology
- Long-Term Effects of COVID-19
- Psychiatric care and mental health services
- Dementia and Cognitive Impairment Research
- Obsessive-Compulsive Spectrum Disorders
- Alzheimer's disease research and treatments
- Bipolar Disorder and Treatment
- Impact of Technology on Adolescents
- Reflective Practices in Education
- Diabetes Management and Research
- Neurobiology of Language and Bilingualism
- Diet and metabolism studies
- Behavioral Health and Interventions
- Intensive Care Unit Cognitive Disorders
- Peptidase Inhibition and Analysis
Moscow Research and Clinical Center for Neuropsychiatry
2022-2024
City Clinical Hospital
2024
Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology
2020-2021
Merck (Germany)
2020
Major depressive disorder (MDD) is among the most prevalent mental disorders worldwide. Factors causing pathogenesis of MDD include gut microbiota (GM), which interacts with host through gut-brain axis. In previous studies GM in patients, 16S rRNA sequencing was used, provided information about composition but not function. our study, we analyzed whole metagenome data to assess changes both and functional profile GM. We looked at 36 compared that 38 healthy volunteers. Comparative taxonomic...
Background. In 2020, the COVID-19 pandemic evoked a variety of research into virus and its effects on mentalhealth. A mental health psychological problems have been reported: stress, anxiety, depressivesymptoms, insomnia, denial, stigma, anger fear.
 Objectives. To assess level depression distress in general population during lockdownin Russia to reveal factors associated with distress.
 Methods. An online survey was carried out from 22–27 April 2020 (the fourth week lockdown)...
Alexithymia, or deficits in emotion recognition, and metacognitive capacity have been noted both psychosis eating disorders potentially linked to psychopathology. This study sought compare levels of impairments these phenomena their associations with psychopathology groups psychosis. Participants diagnoses a schizophrenia spectrum disorder (SSD; n = 53), anorexia (n 40), bulimia 40) were recruited from outpatient clinics. Alexithymia was measured the Toronto Scale; Ekman Faces Test;...
Objective. To study the personality traits of patients with anorexia nervosa (AN) and bulimia (BN) based on human-structural model by Günter Ammon. The focus is impact these development persistence eating disorders (ED). Material methods. A cross-sectional observational was conducted 131 diagnosed AN (n=72) BN (n=59). used clinical, psychopathological, psychometric, statistical I-structural test Ammon to assess structure. Sixty-four were retested 18 months after treatment. Results. baseline...
Background: Cognitive decline during aging is a factor that inevitably affects everyone. In some older adults, cognitive function declines more rapidly to mild impairment (MCI) and eventually dementia. Our work aimed determine the associations between suicide-related single-nucleotide genetic polymorphisms (SNPs) dynamics in people over 65 years old three-year follow-up. Suicide-related SNPs have already shown an association with dementia our previous study. Methods: The present study...
We investigated the associations of rs4680 COMT, rs6280 DRD3 and rs7322347 5HT2A with youth-onset schizophrenia in Russian population a case-control study, role genotype severity clinical features. The association between (p = 0.0001) is described for first time. Furthermore, we found link females 0.001 p 0.02 respectively) males 0.002). Clinical symptoms were assessed on three scales: Clinician-Rated Dimensions Psychosis Symptom Severity scale, PANSS FAB. Gender differences features are...
The detection of specific markers dementia and mild cognitive decline (MCI) could be the key to disease prevention forehanded treatment. Female gender is one major risk factor for dementia. aim our study was compare serum concentration some factors related lipid metabolism immune system in patients with MCI performed on women >65 years old: controls (n = 75), diagnosed 73) 142). Patients were evaluated using Mini-Mental State Examination, Clock Drawing Test Montreal Cognitive Assessment...
To assess the impact of brief group inpatient psychoeducation interventions on compliance patients with first episode psychosis (FEP) and emergency hospitalization.One hundred fifty-eight treatment 79 control were enrolled into study. All hospitalized emergently due to psychotic condition. Patients in had sessions (5 sessions), received basic only. Before discharge from hospital, accessed PANSS, CGI-S, CGI-I «Medication scale».Patient showed significantly better results than medication scale...
Abstract Objective Schizophrenia may reflect an interactive network of disturbances in cognition. In this study we have examined the relationship between two forms cognition: metacognition and social cognition among a sample with schizophrenia ( n = 41), early episode psychosis 37), major depression 30) gathered Moscow, Russia. Methods Metacognition was assessed Assessment Scale‐Abbreviated. Social Ekman 60 Faces Test Interpersonal Reactivity Index. Verbal memory global psychopathology were...
(1) Background: Older people suffer from cognitive decline; several risk factors contribute to greater decline. We used acquired (COVID-19 infection) and non-modifiable (presence of APOE rs429358 rs7412 polymorphisms) study the progression subjective impairment while observing patients for one year. Cognitive training was as a protective factor. (2) Methods: Two groups subjects over age 65 participated in study: group with decline receiving individuals who did not complain without...
Dementia has enormous implications for patients and the health care system. Genetic markers are promising detecting risk of cognitive impairment. We hypothesized that genetic variants associated with suicide might significantly increase decline because in older adults is often a consequence investigated several single-nucleotide polymorphisms were initially dementia identified APOE gene alleles. The study was performed subjects over age 65: 112 146 healthy volunteers. MMSE score used to...
Self-esteem and depressive symptoms contribute to a lower quality of life in people suffering from eating disorders. However, limited research has examined whether other factors may affect how these variables influence one another over time. Metacognition is previously unexplored determinant that impact the relationships between self-esteem, symptoms, instances
To diagnose mild cognitive impairment, it is crucial to understand whether subjective complaints reflect objective deficits. This question has mostly been investigated in the memory domain, with mixed results. Our study was one of first address for language. Participants were 55-to-93-year-old clinic patients (
To study the relationship of parameters immunity and systemic inflammation with structural magnetic resonance imaging (MRI) in patients mild cognitive impairment (MCI) pre-MCI undergoing neurocognitive rehabilitation to search for candidate markers its effectiveness.
BACKGROUND: Over the past seven years, use of long-acting forms antipsychotic medication has significantly increased in Russia. Specifically, Moscow, from 2016 to 2021, proportion prescribed injectable antipsychotics had more than sevenfold (from 3% 23%). Studies have shown that correct selection target groups for such therapy can reduce frequency relapses requiring hospitalization, lower costs inpatient care, and shift focus multiple drug administrations psychosocial work. AIM: This study...
The aim of the study was to assess relationship between level involvement family patients with anorexia nervosa in therapeutic measures during routine treatment EDC and patients’ compliance treatment. We analyzed 104 cases who were treated at 2022–2023 full-time division, half-time division dispensary division. It found that among whose relatives did not attend psychoeducation events, 66.7% (n=10) continue after discharge from attended events partially completely 15.4% (n=2) 24.3% (n=18)...
Background. The COVID-19 pandemic is a major stressor with predictable negative impacts on mental health, especially for vulnerable populations, which include older people. Emotional disorders, decrease in intellectual, physical, social activity are the risk factors development of cognitive decline people; situation pandemic, influence all these exacerbated. In this regard, it seems relevant to study level emotional disorders and affecting state patients mild impairment (MCI) context...