Eleonora Penza

ORCID: 0000-0002-1027-3235
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About
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Research Areas
  • Cardiac and Coronary Surgery Techniques
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac Valve Diseases and Treatments
  • Cardiac Health and Mental Health
  • Cerebrospinal fluid and hydrocephalus
  • Neurosurgical Procedures and Complications
  • Cardiac Arrhythmias and Treatments
  • Aortic Disease and Treatment Approaches
  • Acute Myocardial Infarction Research
  • Coronary Interventions and Diagnostics
  • Spinal Dysraphism and Malformations
  • Mesenchymal stem cell research
  • Pain Management and Treatment
  • Mechanical Circulatory Support Devices
  • Venous Thromboembolism Diagnosis and Management
  • Infective Endocarditis Diagnosis and Management
  • Cardiac electrophysiology and arrhythmias
  • Angiogenesis and VEGF in Cancer
  • Electrospun Nanofibers in Biomedical Applications
  • Hemodynamic Monitoring and Therapy
  • Cardiovascular Issues in Pregnancy
  • Atrial Fibrillation Management and Outcomes
  • Cardiovascular Health and Risk Factors
  • Aortic aneurysm repair treatments

Centro Cardiologico Monzino
2006-2024

Istituti di Ricovero e Cura a Carattere Scientifico
2013-2015

University of Milan
2006-2007

Saphenous vein graft disease is a timely problem in coronary artery bypass grafting. Indeed, after exposure of the to arterial blood flow, progressive modification wall begins, due proliferation smooth muscle cells intima. As consequence, progressively occludes and this leads recurrent ischemia. In present study we employed novel ex vivo culture system assess biological effects arterial-like pressure on human saphenous structure physiology, compare results those achieved presence constant...

10.1371/journal.pone.0117409 article EN cc-by PLoS ONE 2015-02-17

Saphenous vein (SV) graft disease represents an unresolved problem in coronary artery bypass grafting (CABG). After CABG, a progressive remodelling of the SV wall occurs, possibly leading to occlusion lumen, process termed 'intima hyperplasia' (IH). The investigation cellular and molecular aspects IH progression is primary end-point toward generation occlusion-free vessels that may be used as 'life-long' grafts. While animal transplantation models have clarified some factors, pathology human...

10.1002/term.1798 article EN Journal of Tissue Engineering and Regenerative Medicine 2013-07-30

Abstract Aims Patients with coronary heart disease (CHD) are at very high risk of recurrent events. A strategy to reduce excess might be deliver structured secondary prevention programmes, but their efficacy has been mostly evaluated in the short term and experimental settings. This is a retrospective case–control study aimed assessing, real world, programme reducing long-term event recurrences after artery bypass surgery (CABG). Methods results Programme participants (henceforth ‘cases’)...

10.1093/eurjpc/zwaa060 article EN cc-by-nc European Journal of Preventive Cardiology 2020-11-21

Abstract Background This study was undertaken to compare the in vitro effects of 17β-estradiol on human epicardial coronary arteries, resistance arteries and arterial vessels usually employed as grafts surgical myocardial revascularization. Methods Coronary artery rings (descending artery, right circumflex first septal branch) graft (internal thoracic gastro-epiploic artery) obtained from heart donors with not suitable cardiac transplantation were connected force transducer for isometric...

10.1186/1749-8090-1-46 article EN cc-by Journal of Cardiothoracic Surgery 2006-12-01

Background: Morbidity associated with embolization during cannulation in coronary artery bypass grafts (CABG) is strongly related to patient characteristics/comorbidities, the arterial site and shape of cannula tip.. The desired features an should be prevent those morbid effects focus on achieving higher flows lower pressures. Methods: To evaluate vivo performance two aortic dispersion flow cannulas: Optiflow (Sorin Group, Italy) EZ Glide (Edwards Lifesciences, USA) relation pressures, pump...

10.2459/01.jcm.0000550066.34545.87 article EN Journal of Cardiovascular Medicine 2018-11-01
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