Rezeda I. Tukhbatova
A5082843898- Yersinia bacterium, plague, ectoparasites research
- Bee Products Chemical Analysis
- Bacillus and Francisella bacterial research
- Mycobacterium research and diagnosis
- Forensic and Genetic Research
- Leprosy Research and Treatment
- Genomics and Phylogenetic Studies
- Hepatitis B Virus Studies
- Fungal Biology and Applications
- Forensic Anthropology and Bioarchaeology Studies
- Microbial Natural Products and Biosynthesis
- Microbial Metabolic Engineering and Bioproduction
- Insect and Pesticide Research
- Tannin, Tannase and Anticancer Activities
- HIV Research and Treatment
- Bacterial Genetics and Biotechnology
- Phytochemical compounds biological activities
- Agriculture and Biological Studies
- Plant-Microbe Interactions and Immunity
- Immunotoxicology and immune responses
- Nigella sativa pharmacological applications
- Salmonella and Campylobacter epidemiology
- Bacterial Identification and Susceptibility Testing
- Pharmacogenetics and Drug Metabolism
- Rabies epidemiology and control
Max Planck Institute for Evolutionary Anthropology
2023
Kazan Federal University
2016-2022
Max Planck Institute for the Science of Human History
2016-2022
Kazan Scientific Center
2022
Russian Academy of Sciences
2022
Institute of Archaeology
2016
Tatarstan Academy of Sciences
2016
Abstract The origin of Yersinia pestis and the early stages its evolution are fundamental subjects investigation given high virulence mortality that resulted from past pandemics. Although earliest evidence Y. infections in humans has been identified Late Neolithic/Bronze Age Eurasia (LNBA 5000–3500y BP), these strains lack key genetic components required for flea adaptation, thus making their mode transmission disease presentation unclear. Here, we reconstruct ancient genomes individuals...
Abstract The second plague pandemic, caused by Yersinia pestis , devastated Europe and the nearby regions between 14 th 18 centuries AD. Here we analyse human remains from ten European archaeological sites spanning this period reconstruct 34 ancient Y. genomes. Our data support an initial entry of bacterium through eastern Europe, absence genetic diversity during Black Death, low within-outbreak thereafter. Analysis post-Black Death genomes shows diversification a lineage into multiple...
Modern humans have populated Europe for more than 45,000 years
Ancient DNA traces the history of hepatitis B Hepatitis virus (HBV) infections represent a worldwide human health concern. To study this pathogen, Kocher et al . identified 137 remains with detectable levels dating between 400 and 10,000 years ago. Sequencing analyses these ancient viruses suggested common ancestor 12,000 20,000 There is no evidence indicating that HBV was present in earliest humans as they spread out Africa; however, likely populations before farming. Furthermore, Americas...
Significance The bacterium Yersinia pestis has caused numerous historically documented outbreaks of plague and research using ancient DNA could demonstrate that it already affected human populations during the Neolithic. However, pathogen’s genetic diversity, geographic spread, transmission dynamics this early period Y. evolution are largely unexplored. Here, we describe a set genomes up to 5,000 y old from across Eurasia. Our data two genetically distinct forms evolved in parallel were both...
Hansen's disease (leprosy), widespread in medieval Europe, is today mainly prevalent tropical and subtropical regions with around 200,000 new cases reported annually. Despite its long history appearance historical records, origins past dissemination patterns are still widely unknown. Applying ancient DNA approaches to major causative agent, Mycobacterium leprae, can significantly improve our understanding of the disease's complex history. Previous studies have identified a high genetic...
The second plague pandemic (14th - 18th century AD), caused by the bacterium Yersinia pestis , is infamous for its initial wave, Black Death (1346-1353 and repeated scourges in Europe vicinity until Early Modern Era. Here, we report 32 ancient Y. genomes spanning 14th to 17th AD through analysis of human remains from nine European archaeological sites. Our data support an entry Eastern absence genetic diversity during as well low local outbreaks thereafter. Moreover, post-Black shows...