A5101780694- Metal-Catalyzed Oxygenation Mechanisms
- Advanced Photocatalysis Techniques
- TiO2 Photocatalysis and Solar Cells
- COVID-19 Pandemic Impacts
- Computational Drug Discovery Methods
- Nuclear physics research studies
- Solar-Powered Water Purification Methods
- Metal complexes synthesis and properties
- Copper-based nanomaterials and applications
- Advanced Nanomaterials in Catalysis
- Porphyrin and Phthalocyanine Chemistry
- Free Radicals and Antioxidants
- Vanadium and Halogenation Chemistry
- Membrane Separation Technologies
- Artificial Intelligence in Healthcare and Education
- Liver Disease Diagnosis and Treatment
- Tuberculosis Research and Epidemiology
- DNA and Nucleic Acid Chemistry
- Drug-Induced Hepatotoxicity and Protection
- Digital and Cyber Forensics
- Literature, Musicology, and Cultural Analysis
- Characterization and Applications of Magnetic Nanoparticles
- Explainable Artificial Intelligence (XAI)
- vaccines and immunoinformatics approaches
- Advanced Sensor and Energy Harvesting Materials
Narendra Dev University of Agriculture and Technology
2024
University of Delhi
2014-2024
Defence Materials and Stores Research and Development Establishment
2024
Defence Research and Development Organisation
2024
Kurukshetra University
2024
Dow University of Health Sciences
2024
Sukkur IBA University
2024
Maulana Azad Medical College
2014-2023
Galgotias University
2023
Banaras Hindu University
2023
Nature often utilizes molecular oxygen for oxidation reactions through monoxygenases and dioxygenases. In many of these systems, a high-valent iron(IV)-oxo active species is found. recent years, evidence has accumulated possible iron(IV)-imido iron(V)-nitrido intermediates in enzymatic catalysis, although little known about their activity. this work, we report detailed combined kinetics computational study on the difference reactivity chemical properties nonheme compared with...
Cytochrome P450 enzymes are heme based monoxygenases that catalyse a range of oxygen atom transfer reactions with various substrates, including aliphatic and aromatic hydroxylation as well epoxidation reactions. The active species is short-lived difficult to trap characterize experimentally, moreover, it reacts in regioselective manner substrates leading products, but the origin this regioselectivity poorly understood. We have synthesized model complex studied low-pressure Fourier...
Which is better? The first detailed comparison of the reactivity nonheme iron(IV)–imido versus iron(IV)-oxo intermediates with substrates presented. variant reacts sulfides five times faster than iron(IV)–oxo, whereas reverse trend observed for hydrogen atom abstraction. These trends are analyzed and explained.
A versatile class of heme monoxygenases involved in many vital functions for human health are the cytochromes P450, which react via a high-valent iron(IV) oxo cation radical species called Compound I. One key reactions catalyzed by these enzymes is C═C epoxidation substrates. We report here systematic study into intrinsic chemical properties substrate and oxidant that affect reactivity patterns. To this end, we investigated effect styrene para-substituted I models with either an anionic...
This work presents the first detailed study on mechanistic aspects of halide oxidation by non-heme iron complexes. We show that while iron(III)–hydroperoxo complexes oxidise halides via oxygen atom transfer, corresponding iron(IV)–oxo complex reacts electron transfer.
pH regulates the transmembrane transport of Cl<sup>−</sup> ions by bis(iminourea) derivatives.
Abstract Cysteine dioxygenase is a unique nonheme iron enzyme that involved in the metabolism of cysteine body. It contains an active site with unusual 3‐His ligation to protein, which contrasts structural features common dioxygenases. Recently, some us reported truly biomimetic model for this enzyme, namely trispyrazolylborato iron(II) cysteinato complex, not only has structure very similar enzyme–substrate complex but also represents functional model: Treatment dioxygen leads...
Molecular Property Diagnostic Suite ( $$\text {MPDS}^{\mathrm{TB}}$$ ) is a web tool http://mpds.osdd.net designed to assist the in silico drug discovery attempts towards Mycobacterium tuberculosis (Mtb). has nine modules which are classified into data library (1–3), processing (4–5) and analysis (6–9). Module 1 repository of literature related information available on Mtb. 2 deals with protein target chosen disease area. 3 compound consisting 110.31 million unique molecules generated from...
Objective: To analyse quantitatively the adequacy of demographics clinical information and highlight specific areas neglect, by assessing filling out histopathology request forms.
An alkali metal ion assisted Michael addition reaction between acrylate and amine groups is strategically exploited in the synthesis of a chemically reactive tailored hierarchical topography for addressing important fundamental aspects biomimicked interfaces.
Detection of HEV antigen presents as an interesting low cost, novel, and rapid diagnostic technique to ascertain viremia where facilities for reverse transcriptase polymerase chain reaction (RT PCR) are sparse. This study was undertaken assess the relative efficacy detection by ELISA with currently available tests in patients HEV‐related acute viral hepatitis (AVH) liver failure (ALF). included 36 ALF 64 AVH cases. RNA load were determined RT PCR real time PCR, respectively. Evidence recent...
As per the 2022 global tuberculosis (TB) report, TB ranked among top ten causes of mortality worldwide, surpassing both HIV and malaria in fatalities. It is a communicable disease induced by Mycobacterium (MTB). Herein role molecular modeling tools search for new therapeutics involves quantitative structure-activity relationship (QSAR), pharmacophore modeling, docking. In present work, we compiled approximately 1000 anti-TB candidates from literature, along with their experimentally...
Deoxyribonucleic acid has become the target of interest in recent years for number anticancer and antimicrobial drugs. The interaction drugs with nucleic is one important features pharmacology plays significant role to understand mechanism drug action designing more efficient lesser side effect present study reports some classes compounds explores their molecular DNA using modeling methods such as docking, dynamics simulation (MD) quantum mechanics/molecular mechanics (QM/MM) studies....
The Nanorobotics and cargo transportation application of molecular motors is recent intent. present study explores the Mesalamine/5-aminosalicylic acid/5-ASA drug by motors. Mesalamine an anti-inflammatory used to treat Crohn's disease ulcerative colitis. Conjugate mesalamine polystyrene (Dia.: 3 microm) beads was prepared amide linkage between amine (-NH2) group carboxyl (-COOH) bead. In Fourier Transform Infrared spectra, peaks were observed at 3428.1 1654.0 cm(-1) for N-H C=O stretching...
Summary This prospective study was designed to evaluate whether early changes in actin‐free G c‐globulin levels were associated with complications and outcomes identify factors persistent low acute liver failure ( ALF ). Thirty‐two consecutive patients admitted from O ctober 2011 D ecember 2012 followed up until death or complete recovery. All had serum estimation at admission day three expiry. Logistic regression analysis performed independent predictors of mortality. A receiver operating...
Water, the medium of life, has also served as a sustainable source energy for hundreds years. However, most water-based harvesting techniques relies either on rapid flow or fast evaporation rate molecules. Here, complementary charge transfer activities boron (B-r-GO) and nitrogen (N-r-GO) doped reduced graphene oxide (r-GO) flakes are exploited to extract from serene water resources. B-r-GO N-r-GO samples prepared by annealing sheets with boric acid urea were individually coated cellulose...
Forensic science is a study of to criminals and civil laws. Digital forensics the part forensic relating proof found in computers advanced storage media. examiners gather, protect break down logical confirmations over span examination. information contains data as content, pictures, sound, video so on. These days numerous cybercrime cases, for example, hacking, banking cheats, phishing, email spamming, etc., have developed which are connected with computerized information. Since digital...
A telephonic survey was conducted during May 2020 among 675 farmers across 28 districts of 11 states India to assess farm constraints and income losses lockdown 1.0 2.0. The results indicate that labour availability input accessibility were hurdles, but manageable some extent. However, marketing inflicted 48 19% in total expected perishable non-perishable commodities average loss per household ₹0.93 lakh (28%). Although, support given through PM-KISAN, it not adequate compensate losses....
Download This Paper Open PDF in Browser Add to My Library Share: Permalink Using these links will ensure access this page indefinitely Copy URL Photocatalytic Degradation of Organic Dye by Ceo2/Cnt/Go Hybrid Nanocomposites Under Uv-Light for Wastewater Treatment 21 Pages Posted: 4 Aug 2022 See all articles Surjeet ChahalSurjeet ChahalDIT UniversityLakshita Phoraffiliation not provided SSRNAshok Kumaraffiliation SSRNSuresh SSRNSandeep KumarJC Bose University Science and TechnologyRavi...
In the current business environment, organizations are giving a lot of attention to employee engagement. Therefore, present study’s goal was examine connection between skill, motivation, and opportunity -enhancing HRM practices engagement with respect academic staff working in higher education, Sindh, Pakistan. The studyemploys quantitative research design based on SPSS Smart PLS. Data were gathered from 307 academician education survey approach used gather data for cross-sectional research....