Junjie Xu

ORCID: 0000-0002-1182-9880
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About
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Research Areas
  • Micro and Nano Robotics
  • Geomagnetism and Paleomagnetism Studies
  • Selenium in Biological Systems
  • Epigenetics and DNA Methylation
  • Nanoparticle-Based Drug Delivery
  • Characterization and Applications of Magnetic Nanoparticles
  • Microfluidic and Bio-sensing Technologies
  • Crystallization and Solubility Studies
  • Molecular Communication and Nanonetworks
  • Esophageal and GI Pathology
  • X-ray Diffraction in Crystallography
  • Glycosylation and Glycoproteins Research
  • Gene expression and cancer classification
  • RNA modifications and cancer
  • Nanoplatforms for cancer theranostics
  • Bacillus and Francisella bacterial research
  • Monoclonal and Polyclonal Antibodies Research
  • Magnetic and Electromagnetic Effects
  • Pediatric Hepatobiliary Diseases and Treatments
  • Neonatal Health and Biochemistry
  • Advanced Fiber Laser Technologies
  • Laser-Ablation Synthesis of Nanoparticles
  • Advanced optical system design
  • Histone Deacetylase Inhibitors Research
  • Metabolism and Genetic Disorders

Beihang University
2015-2025

Northwest A&F University
2025

Jilin Medical University
2009-2025

Nanjing Agricultural University
2024

Shandong University
2024

Ningxia University
2023

China Agricultural University
2016-2022

China Pharmaceutical University
2019-2021

Shanxi Agricultural University
2021

National Center for Nanoscience and Technology
2021

PRL secretion from the anterior pituitary gland is inhibited by dopamine produced in tuberoinfundibular neurons of hypothalamus. The activity stimulated PRL; thus, regulates its own a negative feedback mechanism. receptors are expressed on neurons, but intracellular signaling pathway not known. We have observed that mice with disrupted signal transducer and activator transcription 5b gene grossly elevated serum concentrations. Despite this hyperprolactinemia, mRNA levels immunoreactivity...

10.1210/endo.142.9.8385 article EN Endocrinology 2001-09-01

We report a novel microlens array with different curvature unit lenses (MLADC) fabricated femtosecond laser direct writing technology. The MLADC consisted of hexagonal hyperboloid microlenses, which have heights and curvatures from others. unique optical performance imaging focusing capability were demonstrated. An object was imaged at positions the by lenses, as ability adjusting image plane for overall MLADC. In addition, experiment had good agreement simulation results, based on analysis...

10.1364/ol.40.004222 article EN Optics Letters 2015-09-02

Bacterial magnetic particles (BMPs) are an attractive carrier material for immunoassays because of their nanoscale size, dispersal ability, and membrane-bound structure. Antitetrabromobisphenol-A (TBBPA) nanobodies (Nbs) in the form monovalence (Nb1), bivalence (Nb2), trivalence (Nb3) were biotinylated immobilized onto streptavidin (SA)-derivatized BMPs to construct complexes BMP-SA-Biotin-Nb1, -Nb2, -Nb3, respectively. An increasing order binding capability -Nb3 TBBPA was observed. These...

10.1021/acs.analchem.9b04177 article EN Analytical Chemistry 2019-11-25

Magnetosomes (also called bacterial magnetic nanoparticles; BMPs) are biomembrane-coated nanoparticles synthesized by magnetotactic bacteria (MTB). Engineered BMPs fused to protein A (termed ∆F-BMP-FA) bind antibodies (Abs) automatically, and thus provide a series of potential advantages. However, no report so far has systematically evaluated functional applicability genetically engineered BMPs. We properties ∆F-BMP-FA, developed/optimized culture methods for host strain Magnetospirillum...

10.1186/s12951-019-0469-z article EN cc-by Journal of Nanobiotechnology 2019-03-06

Nanoparticles (NPs) decorated with functional ligands are promising candidates for cancer diagnosis and treatment. However, numerous studies have shown that chemically coupled targeting moieties on NPs lose their capability in the biological milieu because they shielded or covered by a "protein corona". Herein, we construct magnetosome recognizes targets cells even presence of protein corona.

10.2147/ijn.s338349 article EN cc-by-nc International Journal of Nanomedicine 2022-02-01

Magnetic-controlled micro-robots have promising applications in disease therapy due to their high targetability and drug utilization. Due unique deformable divisible properties, ferrofluid robots gained much attention microchemical reaction chips micromanipulation. This letter proposes a biocompatible robot validates its potential achieve targeted delivery tumor cell killing. ferrofluidic contains 10 nm oleic acid-coated ferric tetroxide particles vegetable oil has good magnetic...

10.1109/lra.2022.3201696 article EN IEEE Robotics and Automation Letters 2022-08-25

Skeletal muscles, the largest organ responsible for energy metabolism in most mammals, play a vital role maintaining body's homeostasis. Epigenetic modification, specifically histone acetylation, serves as crucial regulatory mechanism influencing physiological processes and metabolic patterns within skeletal muscle metabolism. The intricate process of acetylation modification involves coordinated control acetyltransferase deacetylase levels, dynamically modulating precisely regulating...

10.3389/fphys.2023.1267456 article EN cc-by Frontiers in Physiology 2023-12-08

The development of novel processes for the preparation precious metal-based supported catalysts with good catalytic activity and stability has long been a focus research. Herein, we propose...

10.1039/d5ta00886g article EN Journal of Materials Chemistry A 2025-01-01

Abstract Background Magnetosomes (BMPs) are organelles of magnetotactic bacteria (MTB) that responsible for mineralizing iron to form magnetite. In addition, BMP is an ideal biomaterial widely used in bio- and nano-technological applications, such as drug delivery, tumor detection therapy, immunodetection. The use BMPs create multifunctional nanocomposites would further expand the range their applications. Results this study, we firstly demonstrate extracted can remineralize vitro when it...

10.1186/s12951-022-01532-4 article EN cc-by Journal of Nanobiotechnology 2022-08-06

Cartilage destruction caused by inflammation is a clinical challenge. Many studies have investigated cartilage in adults, but little research was conducted on children. In this study, the protective effect of gold nanoparticles (AuNPs) children realized counteracting chondrocyte apoptosis and extracellular matrix (ECM) degradation young mouse model lipopolysaccharide (LPS)-induced growth plate (GP) damage. Initially, engineered AuNPs can be efficiently absorbed chondrocytes, approximately 20...

10.1016/j.mtbio.2023.100795 article EN cc-by-nc-nd Materials Today Bio 2023-09-15
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