A5053706672- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Advanced Radiotherapy Techniques
- Radiation Therapy and Dosimetry
- Bladder and Urothelial Cancer Treatments
- Occupational and environmental lung diseases
- Urologic and reproductive health conditions
- Radiomics and Machine Learning in Medical Imaging
- Lung Cancer Diagnosis and Treatment
- Pleural and Pulmonary Diseases
- Statistical Methods in Clinical Trials
- Advanced X-ray and CT Imaging
- Radiopharmaceutical Chemistry and Applications
- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Cancer Genomics and Diagnostics
- Cardiac Arrhythmias and Treatments
- Management of metastatic bone disease
- Endometrial and Cervical Cancer Treatments
- Peripheral Artery Disease Management
- Olfactory and Sensory Function Studies
- Effects of Radiation Exposure
- Migraine and Headache Studies
- Economic and Financial Impacts of Cancer
- Colorectal Cancer Screening and Detection
Universitair Ziekenhuis Leuven
2025
KU Leuven
2016-2024
Franco-British Council
2023
San Raffaele University of Rome
2019
University Medical Center Freiburg
2016
Institut de Cancérologie de Lorraine
2016
This study investigates whether focal boosting of the macroscopic visible tumor with external beam radiotherapy increases biochemical disease-free survival (bDFS) in patients localized prostate cancer.In phase III, multicenter, randomized controlled Focal Lesion Ablative Microboost Prostate Cancer trial, 571 intermediate- and high-risk cancer were enrolled between 2009 2015. Patients assigned to standard treatment received 77 Gy (fractions 2.2 Gy) entire prostate. The boost arm an additional...
Purpose or objectivesThe FLAME trial (NCT01168479) showed that by adding a focal boost to conventional fractionated EBRT in the treatment of localized prostate cancer, five-year biochemical disease-free survival increased, without significantly increasing toxicity. The aim present study was investigate association between radiation dose bladder and urethra genitourinary (GU) toxicity grade ≥2 entire cohort.Material methodsThe dose–effect relations dose, separately, GU (CTCAE 3.0) up five...
Background Migraine is much more common in females than males, and occurrence associated with changes female sex hormones. Calcitonin gene-related peptide (CGRP) plays a key role migraine, variations hormones may affect CGRP sensitivity and/or production. Objectives Investigate repeatability, gender differences, influence of the menstrual cycle migraine on CGRP-dependent dermal blood flow (DBF). Methods increases DBF were assessed using laser Doppler perfusion imaging after topical...
Abstract Introduction Stereotactic arrhythmia radioablation (STAR) has emerged as a novel treatment option for patients with ventricular tachycardia (VT) who are either refractory to or have contraindications standard therapies. Purpose To evaluate the efficacy of STAR in VT. Methods The CREVET study is single-centre, prospective investigating safety and treating Eligible participants aged ≥18 years structural heart disease experienced ICD therapy monomorphic VT adding escalating...
Purpose Liquid fiducial markers have shown to be a promising alternative solid gold in terms of imaging artifact reduction, patient comfort, and compatibility with different modalities. This study aims investigate the performance novel BioXmark ® liquid marker for state‐of‐the‐art multimodal used prostate cancer ( PC a) radiotherapy, encompassing kV CT / CBCT , multiparametric MRI x‐ray imaging. In addition, automatic detection motion monitoring during treatment was investigated. Methods A...
In patients with prostate cancer (PCa) histopathologically proven pelvic lymph node (LN) metastasis (pN1) after extended dissection (ePLND), multimodality treatment consisting of the primary tumor and whole radiotherapy (WPRT) combined androgen deprivation therapy (ADT) offers promising results, leading to better cause-specific survival rates compared ADT alone. However, in case more than one LN is invaded by tumor, approximately 40% relapse biochemically clinically. Clinical present...
The integration of auto-segmentation and automated treatment planning methods on a fast-rotating O-ring linac may improve the time efficiency online adaptive radiotherapy workflows. This study investigates whether prostate SBRT with focal boosting could generate plans that are similar quality as those obtained through manual clinical C-arm linacs.
We sought to expand current prediction tools for lymph node invasion in patients with prostate cancer using state-of-the-art available tumor information, including multiparametric magnetic resonance imaging based stage and detailed biopsy information.We selected study who had registered information on ISUP (International Society of Urological Pathology) grading imaging, undergone radical prostatectomy extended pelvic dissection. developed a tool 420 externally validated it 187. A concordance...