Youcui Xu

ORCID: 0000-0002-1367-6507
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About
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Research Areas
  • Nanoplatforms for cancer theranostics
  • Inflammasome and immune disorders
  • Photodynamic Therapy Research Studies
  • Metal-Organic Frameworks: Synthesis and Applications
  • Graphene and Nanomaterials Applications
  • Photoacoustic and Ultrasonic Imaging
  • Heme Oxygenase-1 and Carbon Monoxide
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Genetic and Kidney Cyst Diseases
  • Nanoparticle-Based Drug Delivery
  • Fibroblast Growth Factor Research
  • Sulfur Compounds in Biology
  • Galectins and Cancer Biology
  • Cancer, Stress, Anesthesia, and Immune Response
  • Cancer-related Molecular Pathways
  • Cancer Research and Treatments
  • Biosensors and Analytical Detection
  • Luminescence Properties of Advanced Materials
  • Immune cells in cancer
  • Epigenetics and DNA Methylation
  • Cannabis and Cannabinoid Research
  • Liver physiology and pathology
  • Nanoparticles: synthesis and applications
  • Advanced Photocatalysis Techniques
  • Macrophage Migration Inhibitory Factor

Guangdong Academy of Medical Sciences
2022-2025

Guangdong Provincial People's Hospital
2022-2025

Southern Medical University
2023-2025

Anhui Medical University
2023-2025

University of Science and Technology of China
2016-2023

South China University of Technology
2023

Hefei University
2019-2021

Tumor metastasis remains the primary cause of treatment failure in cancer patients, and high-sensitivity preoperative intraoperative detection occult micrometastases continues to pose a notorious challenge. Therefore, we have designed an situ albumin-hitchhiking near-infrared window II (NIR-II) fluorescence probe, IR1080, for precise subsequent image-guided surgery. IR1080 rapidly covalently conjugates with albumin plasma, resulting stronger brightness upon binding. Moreover,...

10.1021/acs.nanolett.3c01484 article EN Nano Letters 2023-06-07

A novel PB-MoO<sub>3−x</sub> NC has been developed by fabrication of molybdenum oxide within the framework PB, to perform highly efficient synergistic PTT/PDT treatment under a single continuous NIR wave laser.

10.1039/c8tb03148g article EN Journal of Materials Chemistry B 2019-01-01

Abstract Liver fibrosis is the leading risk factor for hepatocellular carcinoma. Both oxidative stress and inflammation promote progression of liver fibrosis, but existing therapeutic strategies tend to focus solely on one issue. Additionally, targeting pathological microstructures often neglected. Herein, an esterase‐responsive carbon quantum dot‐dexamethasone (CD‐Dex) developed therapy simultaneously target microstructures, scavenge reactive oxygen species (ROS), suppress inflammation....

10.1002/smll.202102848 article EN Small 2021-11-10

The high mortality associated with drug-resistant bacterial infections is an intractable clinical problem resulting from the low susceptibility of these bacteria to antibiotics and incidence recurrent infections. Herein, a photosynthetic bacteria-based multiplex system (Rp@Al) composed natural Rhodopseudomonas palustris (Rp) Food Drug Administration-approved aluminum (Al) adjuvant, was developed combat prevent their recurrence. We examined its photothermal performance in vitro vivo...

10.1186/s40824-023-00363-0 article EN cc-by Biomaterials Research 2023-02-09

Elevated macroautophagy/autophagy, typically characterized by increased autophagosome accumulation, occurs in a wide variety of physiological and pathophysiological processes, but the current methodology for studying autophagy aberration native non-transfected cells is rather limited. Here we show that LKT, an engineered molecular probe composed cell-penetrating peptide, LC3-interacting motif aggregation-inducedemission (AIE) luminogen tetraphenylethylene, achieved robust identification...

10.1080/15548627.2023.2235197 article EN Autophagy 2023-08-02

Bismuth-based NP@PVP could potentiate DNA damage and inhibit repair with synchronization spatio-temporally for enhanced chemoradiation therapy.

10.1039/d1bm00157d article EN Biomaterials Science 2021-01-01

Abstract Background: The high mortality associated with drug-resistant bacterial infections is an intractable clinical problem because of the low susceptibility bacteria involved to antibiotics and incidence recurrent infections. Methods: Herein, a photosynthetic bacteria-based multiplex system composed natural Rhodopseudomonas palustris (Rp) Food Drug Administration-approved aluminum adjuvant (Rp@Al), was developed combat prevent their recurrence. We examined its photothermal performance,...

10.21203/rs.3.rs-2361365/v1 preprint EN cc-by Research Square (Research Square) 2022-12-20
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