A5068731144- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Ovarian function and disorders
- Reproductive Health and Technologies
- Prenatal Screening and Diagnostics
- Endometriosis Research and Treatment
- Ectopic Pregnancy Diagnosis and Management
- Sperm and Testicular Function
- Reproductive Health and Contraception
- Reproductive System and Pregnancy
- Gynecological conditions and treatments
- Ovarian cancer diagnosis and treatment
- Uterine Myomas and Treatments
- Renal and related cancers
- Ethics and bioethics in healthcare
- Reproductive Physiology in Livestock
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Congenital Anomalies and Fetal Surgery
- Maternal and Perinatal Health Interventions
- Genetic Syndromes and Imprinting
- Maternal and Neonatal Healthcare
- Sexual Differentiation and Disorders
- Biomedical Ethics and Regulation
- CRISPR and Genetic Engineering
- Male Reproductive Health Studies
Hospital Universitario Dexeus
2004-2020
USP Institut Universitari Dexeus
2008-2019
Sidra Medical and Research Center
2017
Universitat Autònoma de Barcelona
1995-2015
Maastricht University
2010-2011
Seattle Reproductive Medicine
2010
Centro de Infertilidad y Reproducción Humana
2006
The recent introduction of oocyte vitrification has significantly advanced the outcome cryopreservation, leading to clinical results comparable those achieved in IVF using fresh oocytes, as reported by experienced centres. This lead new debate, both professional community and society at large, about acceptability offering this technology reproductively healthy women who want cryopreserve their oocytes against threat time. Given many demands calling for simultaneous realization a relatively...
What progress has been made in fertility preservation (FP) over the last decade?FP techniques have widely adopted decade and therefore establishment of international registries on their short- long-term outcomes is strongly recommended.FP a fundamental issue for both males females whose future may be compromised. Reproductive capacity seriously affected by age, different medical conditions also treatments, especially those with gonadal toxicity. There general consensus need to provide...
Fertility issues should be addressed to all patients in reproductive age before cancer treatment. In men, cryopreservation of sperm offered regardless the risk gonadal failure. women, recommendation fertility preservation individualized based on multiple factors such as urgency treatment, patient, marital status, regimen and dosage
A multicentric study was carried out to analyse in a large series: (i) the chromosomal status of unfertilized oocytes, (ii) errors at fertilization and (iii) complement cleaved embryos. Parameters such as type sterility, maternal age, stimulation treatment, doses gonadotrophins administered oocyte preincubation time before insemination were studied relation incidence chromosome abnormalities. Twenty-six per cent oocytes 29.2% embryos had anomalies. Maternal age significantly increased rate...
ObjectiveTo evaluate the dose–response relationship of a novel recombinant human FSH (rhFSH; FE 999049) with respect to ovarian response in patients undergoing IVF/intracytoplasmic sperm injection treatment; and prospectively study influence initial antimüllerian hormone (AMH) concentrations.DesignRandomized, controlled, assessor-blinded, AMH-stratified (low: 5.0–14.9 pmol/L [0.7–<2.1 ng/mL]; high: 15.0–44.9 [2.1–6.3 ng/mL]) trial.SettingSeven infertility centers four countries.Patient(s)Two...
This Task Force document discusses ethical issues arising with requests for medically assisted reproduction from people in what may be called 'non-standard' situations and relationships.The stresses that categorically denying access to any of these groups cannot reconciled a human rights perspective.If there are concerns about the implications on wellbeing persons involved, including future child, surrogate mother or applicants themselves, have considered light available scientific...
WHAT IS KNOWN ALREADYOocyte vitrification is performed routinely and successfully in IVF oocyte donation programs.
A retrospective cohort study was performed to examine whether, in artificial endometrial preparation for frozen embryo transfer (FET) cycles, progesterone (P) levels the day prior of euploid embryos have an impact on pregnancy outcomes. In a private university clinic, 244 FETs between January 2016 and June 2017 were analyzed. Endometrial achieved with estradiol valerate vaginal micronized progesterone. Serum P measured. multivariable analysis assess relationship serum level outcomes...
Between October 1998 and January 1999, we examined the influence of ultrasound guidance in embryo transfer on pregnancy rate 362 patients from our in-vitro fertilization (IVF)–embryo programme. These were prospectively randomized into two groups: 182 had ultrasound-guided replacement, 180 clinical touch transfer. There no statistically significant differences between groups with respect to age, cause infertility characteristics IVF cycle. The was significantly higher among group (50%)...
Summary A new methodology for blastocyst biopsy that uses a 1.48μm in diode laser is described. Trophectoderm cells are biopsied after laster zona drilling and culture, fixed processed fluorescent situ hybridisation (FISH) analysis. Preliminary results on the efficiency of procedure recovery rate promising. Blastocyst useful tool preimplantation genetic diagnosis (PGD) as it allows more reliable widens diagnostic possibilities account higher number obtained biopsy.
This study aims to report the experiences and attitudes of patients who have undergone preimplantation genetic diagnosis (PGD). The extent which this technique is acceptable individuals for whom it intended relatively unexplored, remains a crucial issue that may ultimately determine value PGD as an alternative prenatal in high-risk couples.An information sheet questionnaire was distributed 67 couples had been treated at Hammersmith Hospital, London Dexeus Institute, Barcelona.One-third...
BACKGROUND: High-order multiple pregnancies (triplets or more) have a large adverse impact on perinatal morbidity and mortality as well important economic consequences. Most triplets higher births are due to ovulation induction alone in combination with intrauterine insemination (IUI) rather than in-vitro fertilization (IVF). The present investigation was undertaken determine whether there were specific variables that related patient clinical characteristics (age of the woman, duration...
Lifestyle is increasingly recognized as an outcome-determining factor in assisted reproduction, not only with regard to the cost-effectiveness but also view of balance benefits and risks, including risks related welfare future child. This document briefly summarizes evidence concerning impact three lifestyle-related factors (obesity, tobacco smoking alcohol consumption) on both natural reproduction (IVF) discusses implications this for practice medically light relevant ethical principles....
Background Fertility rates in Europe are among the lowest world, which may be attributed to both biological and lifestyle factors. Cost reimbursement of fertility treatments vary across Europe, although its citizens enjoy wide access care. Since few regional studies evaluating public support for treatment exist, we conducted Listening IVF (LIFE) survey ascertain perception vitro fertilization (IVF) gamete donation as a infertility European men women. Methods findings This was distributed via...
The structured clinical interview for diagnosis (axis 1) according to the Diagnostic and Statistical Manual Mental Disorders (DSM-III-R) was used assess psychiatric morbidity in 110 infertile patients. They were divided into two groups whether referral service of psychosomatic medicine deemed advisable by physician charge. Psychiatric disorders diagnosed 39 56 (69.6%) patients referred group 13 54 (24.1%) non-referred group. found 61.1% females 21% males. Adjustment 59.6% (31/52) all...
BACKGROUND: Assisted hatching (AH) techniques, designed for facilitating the embryo escape out of zona pellucida (ZP) have been used in IVF centres since 1992. The initial indications AH were patient's age, ZP thickness, high basal FSH and repeated failures. Several retrospective prospective studies assessing these given disparate results. Our aims to evaluate benefits immunosuppressive/antibiotic treatment (IA) patients with either a poor prognosis success, previous implantation failures or...
Fluorescent in-situ hybridization (FISH) of decondensed sperm nuclei has been used directly to evaluate the enrichment efficiency human separation using Sephadex gel filtration and serum albumin (HSA) gradients. Control processed spermatozoa were fixed their decondensed. In-situ was carried out with a Y-specific DNA probe (DYZ1). yielded 52.5% Y-chromosome-bearing spermatozoa, HSA resulted in 49.4% untreated control sample percentage Y 49.3%. Statistical analysis revealed no significant...
Bemfola (follitropin alfa) (Finox AG, Switzerland), a new recombinant FSH, has comparable pharmacological profile to that of Gonal-f (Merck Serono, Germany), the current standard for ovarian stimulation. A randomized, multi-centre, Phase 3 study in women undergoing IVF or intracytoplasmic sperm injection (n = 372) showed yielding similar efficacy and safety profiles Gonal-f. Women aged 20–38 years age were randomized 2:1 receive single, daily, subcutaneous 150 IU dose either This tested...
This Task Force document revisits the debate about ethics of sex selection for non-medical reasons in light relevant new technological developments. First, as a result improvement Microsort® flow cytometry method, there is now proven technique preconception that can be combined both with IVF and IUI. Secondly, scenario where approaches are currently being developed preimplantation genetic screening (PGS) may lead to such becoming routine part all treatment. In professionals will more often...