A5101881217- Cardiovascular Function and Risk Factors
- Cardiovascular Health and Disease Prevention
- Cardiac Imaging and Diagnostics
- Blood Pressure and Hypertension Studies
- Cardiovascular Disease and Adiposity
- Heart Rate Variability and Autonomic Control
- Cerebrovascular and Carotid Artery Diseases
- Sodium Intake and Health
- Angiogenesis and VEGF in Cancer
- Biomarkers in Disease Mechanisms
- Advanced Glycation End Products research
- Optical Imaging and Spectroscopy Techniques
- Heme Oxygenase-1 and Carbon Monoxide
- Ginseng Biological Effects and Applications
- Cardiovascular and Diving-Related Complications
- Liver Disease Diagnosis and Treatment
- Facial Nerve Paralysis Treatment and Research
- Atherosclerosis and Cardiovascular Diseases
- Image and Video Stabilization
- Gout, Hyperuricemia, Uric Acid
- Advanced Measurement and Detection Methods
- Genetic Associations and Epidemiology
- Renal function and acid-base balance
- Simulation and Modeling Applications
- MicroRNA in disease regulation
Dalian Medical University
2014-2025
First Affiliated Hospital of Dalian Medical University
2012-2025
Sun Yat-sen University
2024
Third Affiliated Hospital of Sun Yat-sen University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2023
Beijing University of Technology
2023
Chongqing Jiaotong University
2022
China Huadian Corporation (China)
2010
Ehime University
2000-2003
The appropriate target for systolic blood pressure to reduce cardiovascular risk in older patients with hypertension remains unclear.
Background and Purpose —Mechanical stresses on the arterial wall participate in pathogenesis of atherosclerosis as local factors. The relationships between mechanical forces risk factors for were investigated. Methods evaluated carotid artery 117 patients with including hypertension, dyslipidemia, diabetes mellitus, smoking, well 20 age- sex-matched normal controls. Circumferential tension shear stress Laplace’s law a poiseuillean parabolic model velocity distribution. strain was also force....
The optimal systolic blood pressure (SBP) treatment target in elderly people is full of challenge, and non-adherence one major cause uncontrolled BP. Strategy Blood Pressure Intervention the Elderly Hypertensive Patients (STEP) trial a multi-center, randomized controlled that aims to examine whether an intensive (110 ≤ SBP < 130 mmHg) will provide more benefits lowering cardiovascular events than mild (130 150 among aged 60-80 years. From January 10, 2017 December 31, 2017, 8511 patients...
This study aimed to explore whether circadian rhythm of blood pressure is associated with brachial-ankle pulse wave velocity (baPWV) and brachial artery flow-mediated dilation (FMD) in patients essential hypertension.This cross-sectional included 4,217 hypertension who completed 24-hour ambulatory monitoring, baPWV, FMD. BaPWV FMD were measured evaluate arterial stiffness endothelial dysfunction. Participants divided into dipper, non-dipper, reverse dipping groups according the nocturnal...
Abstract This study aimed to explore whether brachial‐ankle pulse wave velocity (baPWV) and brachial artery flow‐mediated dilation (FMD) or the interaction of both parameters are associated with subclinical target organ damage (STOD) indices in patients essential hypertension. A total 4618 registered from January 2015 October 2020 were included. baPWV FMD measured evaluate arterial stiffness endothelial dysfunction. Whereas left ventricular hypertrophy (LVH), urine albumin‐creatinine ratio...
Ventricular remodeling refers to the structural and functional changes of heart under various stimuli or disease influences may also be accompanied by myocardial fibrosis, where an excessive amount fibrous tissue appears in tissue, affecting heart's normal contraction relaxation. Hypertension is posing potential risk causing injury remodeling. The significance renin-angiotensin-aldosterone system (RAAS) cannot overlooked. Drug targeting RAAS can effectively lower blood pressure reduce left...
Abstract Aims Migraine is a prevalent and incapacitating condition. The association between patent foramen ovale (PFO) migraine-type headaches has been extensively documented. In clinical practice, patients may observe residual shunting after PFO closure. Nevertheless, the underlying mechanisms affecting closure remain unclear. Recent studies have identified left atrial abnormalities, specifically cardiopathy, as an independent risk factor for development of fibrillation (AF), thrombosis,...
Background: Data are limited on the prevalence, distribution, and extent of subclinical atherosclerosis (SCA) in populations with primary hypertension an in-depth evaluation is required to explore impact elevated serum uric acid (SUA) levels systemic SCA. Methods: A total 1,534 individuals blood pressure-controlled registered from January 1, 2015 May 31, 2018 were included. The risk factors SCA carotid, coronary, thoracic, renal territories investigated by Doppler ultrasound computed...
This study aimed to investigate whether increased arterial stiffness, measured by brachial-ankle pulse wave velocity (baPWV) is associated with cancer. A total of 45,627 Chinese adults underwent a baPWV examination. The participants were followed up from 1st January 2012 31st December 2018. Cox proportional hazards model was used assess the association between values and During follow-up duration 172,775.69 person-years, there 553 new cases subjects in highest group showed an risk cancer...
Abstract This study aimed to evaluate the blood pressure (BP) lowing effect of low‐sodium (LS) salt substitution and how influenced by plasma renin concentration (PRC) on middle‐aged elderly hypertensive patients. Three hundred fifty‐two hypertensives were randomized at a 1:1 ratio into LS group normal (NS) group. We compared intergroup changes observed in office measurement (OBPM) home (HBPM). Then, all patients divided tertiles according baseline PRC, aldosterone concentration,...
Safety concerns represented by thermal runaway (TR) have seriously hindered the further development of high-energy lithium-ion batteries. In this work, we designed robust inorganic-rich electrode–electrolyte interphases on single-crystal LiNi0.8Co0.1Mn0.1O2 cathode and graphite anode via adopting an ethylene carbonate (EC)-free electrolyte, which can decrease side reaction between electrodes electrolytes. Ultimately, cell employing EC-free electrolyte maintain 96% initial capacity after 300...
Hypertension (HT) induces left atrial (LA) and ventricular (LV) dysfunction, an increase in arterial stiffness. In this study, we investigated the association between LA-LV-arterial coupling nighttime systolic blood pressure (BP) as well BP circadian rhythm essential hypertension.We enrolled 290 HT patients. All subjects were evaluated by 2- dimensional speckle tracking echocardiography (2DSTE), ambulatory 24 h monitoring (ABPM), brachial-ankle pulse wave velocity (PWV). According to...
Abstract Obesity is a recognized risk factor for heart failure. People with similar weights may have different metabolic health. Notably, insulin resistance hallmark of obesity and feature We aimed to evaluate the effects health status on subclinical left cardiac function. also investigated whether (TyG index) plays role in BMI-linked dysfunction. The study involved 403 volunteers. Hierarchical multiple regression models were used assess associations between obesity, health, overall...
<h3>Background:</h3> Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease characterized by the production of autoantibodies and inflammation that can affect multiple organs systems within body. Patients with SLE are at risk for kidney damage due to different self-characteristics, underlying factors, history, etc. Relevant machine learning modeling predictions will provide adequate support reference information exploration these potential factors. <h3>Objectives:</h3> The...