Tesfaldet H. Hidru

ORCID: 0000-0003-4143-4932
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About
Contact & Profiles
Research Areas
  • Atrial Fibrillation Management and Outcomes
  • Venous Thromboembolism Diagnosis and Management
  • Cardiac Imaging and Diagnostics
  • Cardiac Arrhythmias and Treatments
  • Gout, Hyperuricemia, Uric Acid
  • Cardiovascular Disease and Adiposity
  • Cardiac electrophysiology and arrhythmias
  • Cardiovascular Health and Disease Prevention
  • Cardiovascular Function and Risk Factors
  • Blood Pressure and Hypertension Studies
  • Cerebrovascular and Carotid Artery Diseases
  • Heart rate and cardiovascular health
  • Alcohol Consumption and Health Effects
  • Heart Rate Variability and Autonomic Control
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Cancer, Lipids, and Metabolism
  • Vitamin D Research Studies
  • Acute Ischemic Stroke Management
  • Biomarkers in Disease Mechanisms
  • Cancer Risks and Factors
  • Cardiac Fibrosis and Remodeling
  • COVID-19 epidemiological studies
  • Inflammatory Biomarkers in Disease Prognosis
  • School Health and Nursing Education
  • Cerebral Venous Sinus Thrombosis

First Affiliated Hospital of Dalian Medical University
2018-2025

Dalian Medical University
2016-2025

Dalian University
2022

An unhealthy lifestyle of college students is an important public health concern, but few studies have been undertaken to examine the role socio-cultural differences. For this cross-sectional comparative study, data on students' health-promoting lifestyles (HPL), as measured using Health-Promoting Lifestyle Profile (HPLP-II) scale, and self-rated status (SRH) by Sub-Optimal Health Measurement Scale (SHMS V1.0) were collected from 829 students. The sample included 504 (60.8%) Chinese 325...

10.1186/s12889-017-4411-8 article EN cc-by BMC Public Health 2017-05-19

New-onset atrial fibrillation (NOAF) after acute myocardial infarction (AMI) is common and independently correlated with poor prognosis. The purpose of this study to explore whether cardiomyopathy (ACM) markers improve NOAF risk assessment contribute therapy decision-making prognosis.We retrospectively analyzed 4713 patients AMI without a documented history (AF). We measured ACM including P-wave terminal force in ECG lead V1 (PTFV1), Left dimension (LAD), B-type natriuretic peptide (BNP)....

10.1016/j.ejim.2022.04.019 article EN cc-by European Journal of Internal Medicine 2022-05-02

Recurrence after atrial fibrillation (AF) ablation is still common. This study aimed to evaluate the predictive abilities of AF duration and early recurrence (ER) discriminate high-risk patients for recurrence. We enrolled 1,763 consecutive with who were scheduled receive index radiofrequency catheter (RFCA) from January 2016 August 2021 in Dalian, China. Long (LAFD) was considered if course lasted ≥ 12 months. ER defined as any tachycardia (AT) or event longer than 30 s occurring within a...

10.3389/fcvm.2022.864417 article EN cc-by Frontiers in Cardiovascular Medicine 2022-03-25

This study aimed to explore whether circadian rhythm of blood pressure is associated with brachial-ankle pulse wave velocity (baPWV) and brachial artery flow-mediated dilation (FMD) in patients essential hypertension.This cross-sectional included 4,217 hypertension who completed 24-hour ambulatory monitoring, baPWV, FMD. BaPWV FMD were measured evaluate arterial stiffness endothelial dysfunction. Participants divided into dipper, non-dipper, reverse dipping groups according the nocturnal...

10.1080/10641963.2023.2229535 article EN cc-by-nc Clinical and Experimental Hypertension 2023-06-26

Background Serum uric acid (SUA) and lipid metabolism disorders are closely associated with atrial fibrillation (AF) its prognosis. In patients non-valvular AF (NAF), we evaluated the combined predictive value of SUA, triglycerides (TG), low-density lipoprotein (LDL) for stroke to enhance risk prediction management. Methods results We included 3,176 NAF treated at First Affiliated Hospital Dalian Medical University from January 2020 December 2023. analyzed SUA concentration profile, along...

10.3389/fcvm.2025.1569904 article EN cc-by Frontiers in Cardiovascular Medicine 2025-03-26

Abstract This study aimed to explore whether brachial‐ankle pulse wave velocity (baPWV) and brachial artery flow‐mediated dilation (FMD) or the interaction of both parameters are associated with subclinical target organ damage (STOD) indices in patients essential hypertension. A total 4618 registered from January 2015 October 2020 were included. baPWV FMD measured evaluate arterial stiffness endothelial dysfunction. Whereas left ventricular hypertrophy (LVH), urine albumin‐creatinine ratio...

10.1111/jch.14447 article EN Journal of Clinical Hypertension 2022-03-03

Abstract Plasma markers have been continuously advocated as pointers to estimate the long-term risk of cardiovascular disease in general population. We examined relationship between plasma high-sensitivity C-reactive protein (hs-CRP), homocysteine (Hcy), cardiac troponin T (hs-cTnT), N-terminal prohormone brain natriuretic peptide (NT-proBNP), 25-Hydroxyvitamin D (25OHD), glycosylated hemoglobin A1c (HbA1c), and serum uric acid (SUA) levels hypertension middle old aged A total 2624 Chinese...

10.1038/s41598-019-43278-4 article EN cc-by Scientific Reports 2019-05-02

To assess the caregiving burden and its associated factors among Eritrean families of persons living with schizophrenia.A cross-sectional study was conducted for 146 caregivers their respective known patients schizophrenia Saint Mary's Neuropsychiatric National Referral Hospital (SMNNRH). Data were collected using Pai Kapur's Family Burden Interview Schedule (FBIS), Positive Negative Syndrome Scale (PANSS) self-prepared sociodemographic sheet. analysed SPSS V.21. Descriptive statistics,...

10.1136/bmjopen-2016-012127 article EN cc-by-nc BMJ Open 2016-09-01

The occurrence of new-onset atrial fibrillation (NOAF) post-acute myocardial infarction (AMI) is associated with worse outcomes. In this study, we sought to assess the predictive effect stress hyperglycemia ratio (SHR) and neutrophil lymphocyte (NLR) predict NOAF in patients AMI.We recruited 3,194 individuals AMI but free (AF). cases were stratified into groups according SHR NLR quartiles further categorized based on diabetes status. High high defined as highest quartile NLR. A nomogram...

10.3389/fcvm.2022.1051078 article EN cc-by Frontiers in Cardiovascular Medicine 2022-11-09

Despite the availability of Anti-Retroviral Therapy (ART), health-related quality life (HRQoL) among HIV-positive men who have sex with (HIVMSM) in China remains poor. This study aimed to explore relationship between self-reported psychopathology and HRQoL HIVMSM Dalian, China.A cross-sectional was conducted 112 HIVMSM. Symptom check list 90 (SCL 90): a measure World Health Organization HIV infection (WHOQOL-HIV-Bref): were used. Correlation multiple regression analysis employed association...

10.1186/s40249-016-0204-z article EN cc-by Infectious Diseases of Poverty 2016-10-31

Background: Data are limited on the prevalence, distribution, and extent of subclinical atherosclerosis (SCA) in populations with primary hypertension an in-depth evaluation is required to explore impact elevated serum uric acid (SUA) levels systemic SCA. Methods: A total 1,534 individuals blood pressure-controlled registered from January 1, 2015 May 31, 2018 were included. The risk factors SCA carotid, coronary, thoracic, renal territories investigated by Doppler ultrasound computed...

10.3389/fcvm.2021.638992 article EN cc-by Frontiers in Cardiovascular Medicine 2021-04-15

Background: Recent studies have reported the prevalence of cardiovascular diseases (CVDs) among cancer patients following use vascular endothelial growth factor (VEGF) signaling inhibitors. However, data for with a history before active treatment are lacking. This study aims to investigate distribution CVD-related comorbidities in potential VEGF antagonists candidates. Methods: A total 22 500 newly diagnosed registered from 1 January 2011 31 December 2017 were included. Cancer colorectal...

10.1097/hjh.0000000000002277 article EN cc-by-nc-nd Journal of Hypertension 2019-10-04

To investigate the association between serum 25-hydroxyvitamin D (25-[OH]D) concentrations and metabolic syndrome (MetS) in middle-aged elderly Chinese population.

10.1111/jdi.13086 article EN cc-by Journal of Diabetes Investigation 2019-05-30

Background: The predictive power of the CHADS2 and CHA2DS2-VASc scores for presence Left atrial thrombus (LAT)/ spontaneous echo contrast (SEC) in non-valvular fibrillation (NVAF) is modest. aim this analysis to define clinical ultrasonic variables associated with LAT/SEC propose nomograms individual risk prediction. Methods: Data on 1,813 consecutive NVAF patients who underwent transesophageal echocardiography (TEE) from January 2016 2021 were collected. univariate multivariate logistic...

10.3389/fcvm.2021.737551 article EN cc-by Frontiers in Cardiovascular Medicine 2021-10-14

Resting heart rate (RHR) and SBP are important risk markers for all-cause mortality. However, the link between increased RHR all causes of death remained unclear. We investigated an visit-to-visit variation mortality in general population.We examined long-term blood pressure among 46 751 residents Tangshan city, China (mean age: 52.58 ± 11.64 years; 78% men). Cox proportional hazard model was used to estimate ratios 95% confidence interval (CI) adjusting clinical characteristics assessed at...

10.1097/hjh.0000000000001857 article EN cc-by-nc-nd Journal of Hypertension 2018-07-13

Objective: Both serum uric acid (SUA) levels and left atrium diameter (LAD) associate with AF. However, the influence of SUA status for associated risk AF related to LAD in hypertension patients is currently unknown. Methods: We retrospectively analyzed a hospital-based sample 9,618 patients. Standard electrocardiograms were performed on all interpreted by expert electro-physiologists. Results: Overall 1,028 (10.69%) had out In men >65 years age, prevalence the1st, 2nd, 3rd tertiles...

10.3389/fcvm.2020.594788 article EN cc-by Frontiers in Cardiovascular Medicine 2020-11-27

This study aimed to investigate whether increased arterial stiffness, measured by brachial-ankle pulse wave velocity (baPWV) is associated with cancer. A total of 45,627 Chinese adults underwent a baPWV examination. The participants were followed up from 1st January 2012 31st December 2018. Cox proportional hazards model was used assess the association between values and During follow-up duration 172,775.69 person-years, there 553 new cases subjects in highest group showed an risk cancer...

10.3389/fcvm.2023.1112047 article EN cc-by Frontiers in Cardiovascular Medicine 2023-03-01

Elevated resting heart rate (RHR) predicts all-cause death. However, the relationship between RHR variation over years and mortality are still unknown. We aimed to analyze association in general population without cardiovascular diseases. A total of 46,873 subjects were included from Kailuan Study (2006-2011). readings taken during three separate examinations was defined using standard deviation (RHR-SD) coefficient variation. Participants divided into four groups according quartiles RHR-SD....

10.1038/s41598-017-07309-2 article EN cc-by Scientific Reports 2017-08-08

Objective Serum uric acid (SUA) has been associated with cardiovascular diseases, including atherosclerosis and carotid artery stenosis. However, data on the relationship between SUA level proximal extracranial stenosis (PEAS) are limited. Therefore, this study investigates association levels risk of PEAS in asymptomatic Chinese population. Setting This community-based cross-sectional was conducted Jidong Community Hospital, Tangshan, Hebei, China July 2013 August 2014. Participants The...

10.1136/bmjopen-2017-020681 article EN cc-by-nc BMJ Open 2018-08-01

Arsenic was an established carcinogen and toxicant, occurring in drinking water food. increasingly being blamed as a risk factor for diabetes mellitus. Recent studies have found that arsenic could induce the generation of reactive oxygen species (ROS) mitochondria were major targets ROS. Damage be removed by mitophagy played defensive role against cellular apoptosis. To investigate whether injury mitochondria, we treated Wistar rat offsprings INS-1 cells with As2O3 sodium arsenite,...

10.1016/j.biopha.2018.10.134 article EN cc-by-nc-nd Biomedicine & Pharmacotherapy 2018-11-05

Background Elevated long-term systolic blood pressure and resting heart rate (RHR) variability are suggested to amplify the risk of all-cause mortality (ACM). However, link between increased RHR pulse for ACM remained unclear. Methods Results This study analyzed 46 751 individuals from Kailuan Cohort Study end outcome ACM. A Cox regression model was used estimate hazard ratios death events. Kaplan-Meier analysis performed differences in survival as stratified by SD, coefficient variation,...

10.1161/jaha.119.014122 article EN cc-by-nc-nd Journal of the American Heart Association 2020-03-16
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