A5100655420- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Esophageal and GI Pathology
- Chemical Synthesis and Analysis
- Cardiovascular Syncope and Autonomic Disorders
- Cancer, Hypoxia, and Metabolism
- Gastroesophageal reflux and treatments
- Chronic Obstructive Pulmonary Disease (COPD) Research
- ECG Monitoring and Analysis
- Dietary Effects on Health
- Peroxisome Proliferator-Activated Receptors
- Prostate Cancer Treatment and Research
- Heart Rate Variability and Autonomic Control
- Receptor Mechanisms and Signaling
- Pancreatic function and diabetes
- Mitochondrial Function and Pathology
- Advanced biosensing and bioanalysis techniques
- Cancer Immunotherapy and Biomarkers
- Diabetes Treatment and Management
- Venous Thromboembolism Diagnosis and Management
- Heart Failure Treatment and Management
- Cardiac Imaging and Diagnostics
- Cancer-related molecular mechanisms research
Dalian Medical University
2016-2025
First Affiliated Hospital of Dalian Medical University
2016-2025
Nankai University
2025
State Key Laboratory of Medicinal Chemical Biology
2025
Soochow University
2023-2024
Dalian University
2022
Dimensional Imaging (United Kingdom)
2019
Creative Commons
2019
Shaoxing People's Hospital
2018
Shandong Provincial Institute of Dermatology and Venereology
2006
Catheter ablation (CA) for atrial fibrillation (AF) in heart failure patients with preserved ejection fraction (HFPEF) has shown promising results reducing mortality and improving function. However, previous studies have been limited by a lack of control groups significant heterogeneity their methodologies. CA AF HFPEF may not increase the complications had similarly rate freedom from vs. without HFPEF, it reduce hospitalizations improve function VS medical treatment. Three were included...
Recurrence after atrial fibrillation (AF) ablation is still common. This study aimed to evaluate the predictive abilities of AF duration and early recurrence (ER) discriminate high-risk patients for recurrence. We enrolled 1,763 consecutive with who were scheduled receive index radiofrequency catheter (RFCA) from January 2016 August 2021 in Dalian, China. Long (LAFD) was considered if course lasted ≥ 12 months. ER defined as any tachycardia (AT) or event longer than 30 s occurring within a...
Whether the intraprocedural anticoagulation regimen and activated clotting time (ACT) in pulsed field ablation (PFA) for atrial fibrillation (AF) are same as those radiofrequency catheter (RFCA) is currently unknown. Our retrospective study included 51 paroxysmal AF patients who underwent PFA (PFA group) were matched with RFCA. Nearest-neighbor propensity score matching was performed at a 1:1 ratio (no tolerance to anticoagulant regimens of 0.02 on CHA2DS2-VASc score, left diameter,...
This study aimed to investigate the association between essential hypertension and incidence of erosive esophagitis (EE) using data from a single-center hospital cohort. A total 4844 patients who underwent gastroscopy at First Affiliated Hospital Dalian Medical University June 2019 December 2023 were included in this analysis. Participants categorized into two groups: those with without, latter comprising individuals presented neither reflux-related symptoms nor positive endoscopic findings....
Long-term complications occur in approximately 4%-12% of patients with standard transvenous pacemakers (TVPs), most whom are elderly. The leadless pacemaker (LP) has emerged as an effective alternative to traditional TVPs, offering a lower complication profile. However, data on LP implantation octogenarians remain limited, and concerns persist regarding its feasibility safety this population. This study aimed assess the clinical outcomes octogenarians. Between January 2021 2024, 154 (mean...
We assessed the impact of pre- and postprocedural plasma corin levels on recurrence atrial fibrillation (AF) after catheter ablation (CA).
Aims: Catheter ablation should be considered in patients with atrial fibrillation (AF) and heart failure (HF) reduced ejection fraction (EF; HFrEF) to improve survival reduce hospitalization. Careful patient selection for AF is key achieving similar outcome benefits. However, limited data exist regarding predictors of recovered fraction. We aimed evaluate the consecutive HF undergoing ablation. Methods Results: A total 156 [67.3% men, median age 63 (11)] underwent initial catheter between...
Abstract Objective Ablation index (AI) is an effective ablation quality marker. Impedance also important factor for lesion formation. The present study evaluated the influence of baseline impedance in effect atrial fibrillation (AF) guided by AI. Methods This was a retrospective study. 101 patients with paroxysmal AF (PAF) were enrolled. All underwent radiofrequency same AI strategy. strategy pulmonary vein (PV) isolation non-PV triggers ablation. points recorded. followed up every 3 months...
Pulmonary vein (PV) occlusion generally depends on repetitive contrast agent injection when cryoballoon ablation for atrial fibrillation (AF). The present study was to compare the effect of AF guided by transesophageal echocardiography (TEE) vs. injection.Eighty patients with paroxysmal (PAF) were enrolled in study. About 40 underwent without TEE (non-TEE group) and other PV (TEE group). In group during procedure, PVs displayed 3-dimensional images guide balloon achieve occlusion. followed...
Cavotricuspid isthmus (CTI) ablation is an effective procedure for typical atrial flutter (AFL), but patients remain at elevated risk developing new fibrillation (AF). Currently, there are limited data on the utility of CHA2DS2-VASc score to predict new-onset AF after AFL ablation. In this study, we assessed whether a useful predictor CTI in without prior history AF.This was retrospective study 103 with no AF, who underwent successful The endpoint occurrence during follow-up.During mean...
Abstract Background Atrioventricular node (AVN) ablation combined with His bundle pacing is an effective strategy for permanent atrial fibrillation (AF) rapid ventricular rate refractory to pharmacological therapy. We aimed access the feasibility and efficiency of AVN guided by three‐dimensional (3‐D) mapping system throughout procedure. Methods Eighteen patients AF symptoms were referred 3‐D (CARTO3). Electroanatomic right atrium ventricle was performed catheter CARTO 3 system, followed...
Background: The mechanisms for the vein of Marshall (VOM) mediated atrial fibrillation (AF) are not completely understood. We sought to evaluate contribution intrinsic cardiac autonomic nervous system in VOM AF. Method: Seven mongrel dogs were administered propranolol and continuously exposed left superior ganglionated plexi (LSGP) stimulation, LSGP + low-level atropine administration, filling with ethanol separately. effective refractory period (ERP) window vulnerability (WOV) at pulmonary...
Uninterrupted warfarin during cryoballoon ablation (CB-A) of atrial fibrillation (AF) has been widely accepted. However, to our knowledge, no previous studies exist investigating the optimal intensity anticoagulation with for CB-A. This study aimed evaluate efficacy and safety uninterrupted low-intensity CB-A AF in elderly.Paroxysmal patients (age ≥ 70 years) who underwent were enrolled prospectively. The participants stratified into 2 groups based on international normalized ratio (INR)...
To explore the safety and efficacy of a novel strategy (bi-atrial linear catheter ablation guided by electrophysiological mapping) for persistent atrial fibrillation (PeAF) treatment. 83 patients with PeAF were enrolled evaluation strategy. 43 subjected to pulmonary vein isolation (PVI) (PVI group). 40 bi-atrial mapping (PVI, left BOX ablation, coronary sinus endocardial tailored anterior wall mitral isthmus necessary ethanol infusion into Marshall, right posterior cavo-tricuspid ablation)...
<title>Abstract</title> <bold>Purpose</bold> Catheter ablation (CA) for atrial fibrillation (AF) in heart failure patients with preserved ejection fraction (HFPEF) has shown promising results reducing mortality and improving function. However, previous studies have been limited by a lack of control groups significant heterogeneity their methodologies. <bold>Hypothesis</bold> CA AF HFPEF may not increase the complications had similarly rate freedom from vs without HFPEF, it reduce...
ABSTRACT Background Transseptal catheterization is critical for atrial fibrillation (AF) ablation but risks thromboembolism. sheaths (TSS) were suggested continuous heparinized saline solution flush. The safety and effectiveness of a simple TSS management to reduce sheath‐associated thrombus development risk was investigated. Methods AF patients who underwent radiofrequency with the studied under retrospective multi‐center observation study prospective single‐center study. dilators washed...
Coronary sinus-related arrhythmias are common; however, it is difficult to perform radiofrequency (RF) ablation at these sites efficiently and safely. High-power, short-duration (HPSD) a proven alternative strategy for pulmonary vein isolation (PVI); whether can be applied of the coronary sinus unknown. The purpose this preliminary study was evaluate feasibility safety HPSD in sinus.Firstly, we demonstrated 4 clinical cases 3 types who had unsuccessful with standard power initially, but...
Atrial fibrillation (AF) is one of the most common arrhythmias which affects 1 in 200 patients worldwide[1] and associated with poor outcomes. Radiofrequency catheter ablation (RFCA) an effective treatment for drug-refractory symptomatic paroxysmal or persistent AF patients[2]. Despite obvious advantage procedural technology, recurrence rate after remained significant ranged from 30 to 60% [3]. Various risk factors have now been identified several scoring systems based on antecedent...