- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Venous Thromboembolism Diagnosis and Management
- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Lung Cancer Treatments and Mutations
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular Syncope and Autonomic Disorders
- Cardiovascular Effects of Exercise
- Heart Rate Variability and Autonomic Control
- Lipoproteins and Cardiovascular Health
- Cardiovascular Disease and Adiposity
- Lung Cancer Research Studies
- Cardiac Imaging and Diagnostics
- Caveolin-1 and cellular processes
- Genetic Associations and Epidemiology
- E-commerce and Technology Innovations
- RNA regulation and disease
- Asthma and respiratory diseases
- Cardiac Structural Anomalies and Repair
- Brain Metastases and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Ultrasound and Hyperthermia Applications
Dalian Medical University
2016-2025
First Affiliated Hospital of Dalian Medical University
2016-2025
Boai Hospital of Zhongshan
2025
Shengli Oilfield Central Hospital
2024
China Rehabilitation Research Center
2023
Capital Medical University
2023
Dalian University
2022
Dimensional Imaging (United Kingdom)
2019
Creative Commons
2019
Catheter ablation (CA) for atrial fibrillation (AF) in heart failure patients with preserved ejection fraction (HFPEF) has shown promising results reducing mortality and improving function. However, previous studies have been limited by a lack of control groups significant heterogeneity their methodologies. CA AF HFPEF may not increase the complications had similarly rate freedom from vs. without HFPEF, it reduce hospitalizations improve function VS medical treatment. Three were included...
Background The association between dyslipidemia, a major risk factor for cardiovascular diseases, and atrial fibrillation (AF) is not clear because of limited evidence. Hypothesis. Dyslipidemia may be associated with increased AF in Chinese population. Methods A total 88 785 participants free from at baseline (2006–2007) were identified the Kailuan Study. Fasting levels cholesterol (TC), low‐density lipoprotein (LDL‐C), high‐density (HDL‐C), triglycerides (TG) measured using standard...
Recurrence after atrial fibrillation (AF) ablation is still common. This study aimed to evaluate the predictive abilities of AF duration and early recurrence (ER) discriminate high-risk patients for recurrence. We enrolled 1,763 consecutive with who were scheduled receive index radiofrequency catheter (RFCA) from January 2016 August 2021 in Dalian, China. Long (LAFD) was considered if course lasted ≥ 12 months. ER defined as any tachycardia (AT) or event longer than 30 s occurring within a...
In atrial fibrillation (AF), a more extensively fibrotic left atrium (LA) provides substrate for arrhythmias and increases risk of relapse following ablation. Fibrocytes are bone marrow-derived circulating mesenchymal progenitors that have been identified in the patients with AF who valvular diseases. The present study investigates associations between fibrocytes LA fibrosis or prevalence recurrence after ablation persistent AF.We measured proportion, differentiation, migration from (n=40),...
Long-term complications occur in approximately 4%-12% of patients with standard transvenous pacemakers (TVPs), most whom are elderly. The leadless pacemaker (LP) has emerged as an effective alternative to traditional TVPs, offering a lower complication profile. However, data on LP implantation octogenarians remain limited, and concerns persist regarding its feasibility safety this population. This study aimed assess the clinical outcomes octogenarians. Between January 2021 2024, 154 (mean...
Background Insomnia is the most prevalent sleep disorder; however, little research has explored link between insomnia and atrial fibrillation ( AF ). Hypothesis associated with increased risk of in a Chinese population. Methods A total 8371 participants (4314 males; mean age, 42.4 ± 13.1 years) were enrolled this cross‐sectional study to investigate association . was assessed standard supine resting position 10‐s 12‐lead electrocardiograph ECG ) or by self‐reported history. using Athens...
Whether the intraprocedural anticoagulation regimen and activated clotting time (ACT) in pulsed field ablation (PFA) for atrial fibrillation (AF) are same as those radiofrequency catheter (RFCA) is currently unknown. Our retrospective study included 51 paroxysmal AF patients who underwent PFA (PFA group) were matched with RFCA. Nearest-neighbor propensity score matching was performed at a 1:1 ratio (no tolerance to anticoagulant regimens of 0.02 on CHA2DS2-VASc score, left diameter,...
Background Severe pneumonia has a poor prognosis and high mortality. Current severity scores such as Acute Physiology Chronic Health Evaluation (APACHE-II) Sequential Organ Failure Assessment (SOFA), have limited ability to help clinicians in classification management decisions. The goal of this study was analyse the clinical characteristics severe develop machine learning-based mortality-prediction model for patients with pneumonia. Methods Consecutive between 2013 2022 admitted Beijing...
Atrial electrical remodeling (AER) is the underlying mechanism of atrial fibrillation (AF). The present study investigated impact epicardial fat pad (FP) ablation on acute AER (AAER) and inducibility AF.AAER was performed in 28 mongrel dogs through 4-h rapid pacing (RAP). Before RAP, 14 (ablation group) underwent FP ablation, other (control a sham procedure. effective refractory period (ERP) vulnerability window (VW) AF were measured with without bilateral cervical vagosympathetic nerve...
Background A prolonged PR interval is a sign of increased risk cardiac arrhythmia. Recent genome-wide association studies found that the single-nucleotide polymorphism (SNP) rs3825214 in T-box 5 (TBX5) was positively associated with interval, QRS duration, QT and common arrhythmia disorders such as atrial fibrillation (AF) advanced atrioventricular block. However, other independent replication are required to validate result. This study assessed associations between ECG parameters, AF,...
The relationship between cumulative non-high-density lipoprotein cholesterol (non-HDL-C) burden and atherosclerotic cardiovascular disease (ASCVD) remains unclear.To prospectively examine the association non-HDL-C ASCVD risk in Kailuan cohort of China.A total 49,679 subjects who were free participated three consecutive examinations 2006, 2008 2010 enrolled. Duration concentration exposure to (cumNon-HDL-C) respectively used estimate extent burden. participants divided into four groups...
Background The Cardiovascular Health (CVH) Score was comprised of a series modifiable lifestyle and health factors, which published by American Heart Association in 2010. Its relationship with atrial fibrillation (AF) remains unclear. Hypothesis Individuals higher CVH had lower risk AF. Methods Participants ≥40 years age were recruited from the Jidong community. Information regarding following 7 metrics, including smoking, body mass index, diet, physical activity, total cholesterol, fasting...
Backgrounds . Segmental and circumferential pulmonary vein isolations (SPVI CPVI) have been demonstrated to be effective therapies for paroxysmal atrial fibrillation (PAF). PVI is well established as the endpoint of different ablation techniques, whereas it may not completely account long‐term success. Methods 181 drug‐refractory symptomatic PAF patients were referred segmental or = 67; CPVI 114). Heart rate variability (HRV) was assessed before after final ablation. Results After following...
Background: The predictive power of the CHADS2 and CHA2DS2-VASc scores for presence Left atrial thrombus (LAT)/ spontaneous echo contrast (SEC) in non-valvular fibrillation (NVAF) is modest. aim this analysis to define clinical ultrasonic variables associated with LAT/SEC propose nomograms individual risk prediction. Methods: Data on 1,813 consecutive NVAF patients who underwent transesophageal echocardiography (TEE) from January 2016 2021 were collected. univariate multivariate logistic...
Electrocardiographic (ECG) characteristics of patients with isolated hypomagnesemia are not well defined. We aimed to investigate these ECG in order define clearly the features hypomagnesemia. Lower serum magnesium could affect parameters after excluding potential confounders. This retrospective study was low <0.65 mmol/L compared same restoration normal magnesium. Patients hypokalemia, hypocalcemia and other electrolyte disturbances were excluded. manually determined analyzed P wave...
Background Growing evidence indicates that advanced glycation end-product receptor (RAGE) might play a contributory role in the pathogenesis of coronary artery disease (CAD). To shed some light from genetic perspective, we sought to investigate interactive association RAGE gene four common polymorphisms (rs1800625 or T-429C, rs1800624 T-374A, rs2070600 Gly82Ser, and rs184003 G1704A) with risk developing CAD large northeastern Han Chinese population. Methodology/Principal Findings This was...
The coronary sinus (CS), as a junction of the atria, contributes to atrial fibrillation (AF) by developing unstable reentry, and isolating atria ablation at CS could terminate AF. present study evaluated whether AF activities in subset patients contributed maintenance predicted clinical outcome ablation.We studied 122 consecutive who had first-time radiofrequency for persistent Bipolar electrograms were obtained from multiple regions left atrium Lasso mapping catheter before ablation....
Aims: Catheter ablation should be considered in patients with atrial fibrillation (AF) and heart failure (HF) reduced ejection fraction (EF; HFrEF) to improve survival reduce hospitalization. Careful patient selection for AF is key achieving similar outcome benefits. However, limited data exist regarding predictors of recovered fraction. We aimed evaluate the consecutive HF undergoing ablation. Methods Results: A total 156 [67.3% men, median age 63 (11)] underwent initial catheter between...