A5100389205- Acute Myocardial Infarction Research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Heart Rate Variability and Autonomic Control
- Diabetes Treatment and Management
- Medical Research and Treatments
- Cardiovascular Effects of Exercise
- Heart Failure Treatment and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Respiratory Support and Mechanisms
- Cardiac tumors and thrombi
- Treatment of Major Depression
- Diet and metabolism studies
- Non-Invasive Vital Sign Monitoring
- Coronary Interventions and Diagnostics
- Metabolism, Diabetes, and Cancer
- Neuroendocrine Tumor Research Advances
- Lymphoma Diagnosis and Treatment
- Cardiac Arrhythmias and Treatments
- Cardiac Imaging and Diagnostics
- Cervical Cancer and HPV Research
- Cardiovascular Function and Risk Factors
- Blood Pressure and Hypertension Studies
- Voice and Speech Disorders
- Restless Legs Syndrome Research
- Hair Growth and Disorders
Capital Normal University
2025
Henan University
2025
Tianjin University
2024
First Affiliated Hospital of GuangXi Medical University
2023-2024
Guangxi Medical University
2023-2024
Tianjin Chest Hospital
2020-2024
Washington University in St. Louis
2022-2024
Harbin Institute of Technology
2024
Sichuan University
2023
Sun Yat-sen Memorial Hospital
2022
Myocardial ischemia-reperfusion (IR) injury is a severe rhythmic disease with high prevalence in the early morning. IR has significant circadian rhythm reactive oxygen species (ROS) and inflammation levels. The development of drugs become priority myocardial injury. In this study, resveratrol (RES) proanthocyanidins (OPC) were utilized to design nanoparticles (NPs), hyaluronic acid (HA) as core, grafted MMP-targeting peptides improve delivery injured regions (HA-RES-OPC-MMP NPs). NPs...
Abstract Background Stress hyperglycemia ratio (SHR) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are independently associated with increased mortality risk in diabetic patients coronary artery disease (CAD). However, the role of these biomarkers diabetes multivessel (MVD) remains unknown. The present study aimed to assess relative combined abilities predict all-cause MVD. Methods This included 1148 MVD who underwent angiography at Tianjin Chest Hospital between January 2016...
With the aging of China's population and lifestyle changes, number patients with type 2 diabetes (T2D) has surged, posing a significant challenge to public health system. This study explores application effectiveness artificial intelligence (AI) technology in T2D management from Chinese perspective. AI demonstrates substantial potential personalized treatment planning, real-time monitoring early warning, telemedicine, management. It not only enhances precision convenience but also aids...
As the global population ages, China faces unique challenges due to its rapid economic development and societal changes. The older adult in China, especially females, is growing rapidly, with women outnumbering men age groups. Gender disparities aging manifest physiological, psychological, social aspects, including higher risks of cardiovascular diseases adultmen osteoporosis women. China’s rapidly profound gender health outcomes, shaped by biological, social, cultural determinants....
Lipid lowering properties of glucagon have been reported. Blocking signaling leads to rise in plasma LDL levels. Here, we demonstrate the lipid effects acute dosing with Glp1r/Gcgr dual agonist (DualAG). All experiments were performed 25 week-old male diet-induced (60% kCal fat) obese mice. After 2 hrs fasting, mice injected subcutaneously vehicle, liraglutide (25nmol/kg) and DualAG (25nmol/kg). De novo cholesterol palmitate synthesis was measured by deuterium incorporation method using D2O....
Abstract Cases of atopic dermatitis (AD)‐like rash induced by IL‐17A inhibitor secukinumab treatment (SI‐AD) have been recently reported in psoriasis patients. To identify immune and inflammatory factors expression SI‐AD. A panel 15 peripheral blood samples from various groups, including patients with SI‐AD, (S‐stable), advanced (Advanced) healthy controls (HC). Interleukin‐10 (IL‐10), IL‐4 were detected skin tissue biopsy immunohistochemistry real‐time quantitative polymerase chain...
Abstract We aimed to determine whether hs-CRP is a predictor of future premature ventricular contraction (PVC) events in community based population. A total 101,510 participants were recruited at baseline (2006–2007). The follow-up visits conducted every two years. Participants who free from PVC and achieved the fourth visit, or diagnosed during subsequent included for analyses. Diagnosis was on standard supine resting, 10-s 12-lead ECG. Cox regression applied evaluate association between...
We conducted a longitudinal study (from February 2017 to July 2017) explore whether the triglyceride glucose index (TyG) has prognostic value for major adverse cardiovascular events (MACE) among high-risk Chinese hypertensives. The population were from 6 districts of Tianjin, China. Finally, total 2250 patients enrolled in this 3.5 year cohort study. divided into two groups according cut-off TyG index: Low-TyG group (n = 901, ≤ 8.87), High-TyG 1349, > 8.87). Univariate and multivariate Cox...
To investigate the prevalence of genital high-risk human papillomavirus (HR-HPV) in male sexual partners HR-HPV infected women and concordance viral types couples China, comprehend role men play HPV transmission to women.94 asymptomatic their husbands from rural Chaozhou participated epidemiologic screening for infection. Cervical cells females were collected high risk by real time-PCR, they positive at least 1 13 subtypes, then these samples genotyped. Approximately one mouth later, penile...
The optimal interventional strategy remains undetermined in hemodynamically stable patients with NSTEMI and MVD. This study aimed to examine clinical prognosis among culprit vessel, immediate multivessel, staged percutaneous coronary intervention (PCI) MVD.This retrospective, observational, single-center included 943 MVD who had undergone successful drug-eluting stent (DES) implantation from January 2014 December 2019. Patients were categorized into lesion-only PCI (CL-PCI), multivessel...
Elevated resting heart rate (RHR) predicts all-cause death. However, the relationship between RHR variation over years and mortality are still unknown. We aimed to analyze association in general population without cardiovascular diseases. A total of 46,873 subjects were included from Kailuan Study (2006-2011). readings taken during three separate examinations was defined using standard deviation (RHR-SD) coefficient variation. Participants divided into four groups according quartiles RHR-SD....
Objective. Frequent cessations of respiration can greatly increase the prevalence rate arrhythmia. It has been confirmed that cardiac modulation is regulated by autonomic nervous system (ANS). And heart variability (HRV) widely used as a method to evaluate function ANS. Therefore, we analyzed whether apnea affect balance and normal ANS using short-term HRV indices. Methods. Forty-five healthy subjects were asked breathe normally hold their breathing simulate 10 times apnea. Thirty-six...
The present study aims to evaluate how nutritional status may affect transcatheter aortic valve implantation (TAVI) outcomes.This is a retrospective of 383 TAVI patients. In-hospital, 1-month, and 12-month survival was evaluated. Since most patients undergoing are over 75 years old, the NRI definition for geriatric population (GNRI) used. Preoperative baseline clinical laboratory data were collected then corresponding calculated, including Geriatric Nutritional Risk Index (GNRI), Prognostic...
Acute coronary syndrome (ACS) without standard modifiable cardiovascular risk factors (SMuRFs) represents a special case of ACS. Multiple biomarkers have been shown to improve stratification in patients with However, the utility for prognostic ACS SMuRFs remains uncertain. The aim present study was evaluate value various patents SMuRFs.Data consecutive who underwent angiography Tianjin Chest Hospital between January 2014 and December 2017 were retrospectively collected. primary outcome...
Tobacco-specific nitrosamines (TSNAs) are a group of toxic substances specific to tobacco. 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) is tobacco-specific nitrosamine measurable in urine with much longer half-life than cotinine. We aimed examine the association between urinary NNAL and HPV infection among American women. used cross-sectional data from National Health Nutrition Examination Survey (NHANES) 2007 2014 collect details on their NNAL, status, other essential variables. The...
Abstract Artificial intelligence (AI) is revolutionizing scientific discovery because of its super capability, following the neural scaling laws, to integrate and analyze large-scale datasets mine knowledge. Foundation models, large language models (LLMs) vision (LVMs), are among most important foundations paving way for general AI by pre-training on massive domain-specific datasets. Different from well annotated, formatted integrated textual image LLMs LVMs, biomedical knowledge fragmented...
The article aims to discuss the feasibility of using respiratory sounds monitor rate. average power was created firstly, autocorrelation algorithm used calculate cycle. cycle nasal flow pressure signal calculated simultaneously, and result taken as a reference standard, then, two groups data were analyzed by correlation analysis Bland-Altman analysis. rate is relatively stable, feasible, changes obviously, existing methods are temporarily unable accurately reflect rate, further research needed.