A5042271371- Antibiotic Resistance in Bacteria
- Pneumonia and Respiratory Infections
- COVID-19 Clinical Research Studies
- Antibiotic Use and Resistance
- Bacterial Infections and Vaccines
- Antifungal resistance and susceptibility
- Animal Disease Management and Epidemiology
- Vibrio bacteria research studies
- Antimicrobial Resistance in Staphylococcus
- Bacterial biofilms and quorum sensing
- Plant Pathogens and Fungal Diseases
- Health Literacy and Information Accessibility
- Essential Oils and Antimicrobial Activity
- Virus-based gene therapy research
- Ocular Infections and Treatments
- Dermatological and COVID-19 studies
- Escherichia coli research studies
- Pharmaceutical and Antibiotic Environmental Impacts
- Antibiotics Pharmacokinetics and Efficacy
- Viral gastroenteritis research and epidemiology
- Cystic Fibrosis Research Advances
- Tuberculosis Research and Epidemiology
- Immunodeficiency and Autoimmune Disorders
- Nail Diseases and Treatments
- Monoclonal and Polyclonal Antibodies Research
University of Trieste
2003-2024
Azienda Sanitaria Universitaria Integrata di Trieste
2022-2023
University of Verona
2006-2016
Northampton Community College
2010
Antibiotic resistance is an increasing community problem and related to antibiotic use. If use could be reduced, the tide of stemmed. e-Bug a European project involving 18 countries, partly funded by The Directorate-General for Health Consumers (DG SANCO) Commission. It aims develop disseminate across Europe junior senior school teaching pack web site (hosting lesson plans complementary games) that teach young people about prudent use, microbes, transmission infection, hygiene vaccines. aim...
As a complement to the e-Bug teaching pack, two games were developed provide content that aimed entertain as well educate. A set of agreed learning outcomes (LOs) provided by scientific partners Project and using user-centred design techniques (the needs, wants limitations potential game players assessed at each stage process). The designed for age groups: Junior (9–12 year olds); Senior (13–15 olds). study focus groups was done gain an understanding types enjoyed target users. According...
e-Bug, a junior and senior school educational programme to decrease the spread of infection unnecessary antibiotic use, was developed consisted eight sections providing information on spread, treatment prevention as well basic microbes, both useful harmful. Each section comprised teacher background information, lesson plans an interactive student activity, extension activities were also available for more able students. This study aimed evaluate effectiveness e-Bug pack in improving...
Purpose. Obesity is a risk factor for severe coronavirus disease 2019 (COVID-19). Circulating adipokines have been associated with inflammatory burden and amplified or dysregulated immune responses. This study aimed to evaluate the discriminatory ability of identify COVID-19 pneumonia assess severity. Methods. We conducted an observational case-control study, prospective design, recruited patients diagnosis (n = 48) healthy controls 36), who were matched by age, sex, BMI. Leptin,...
The continuous emergence of SARS-CoV-2 variants and subvariants poses significant public health challenges. latest designated subvariant JN.1, with all its descendants, shows more than 30 mutations in the spike gene. JN.1 has raised concerns due to genomic diversity potential enhance transmissibility immune evasion. This study aims analyse molecular characteristics JN.1-related lineages (JN.1*) identified Italy from October 2023 April 2024 evaluate neutralization activity against a subsample...
Health promotion interventions aimed at children and young people have the potential to lay foundations for healthy lifestyles. One such intervention, e-Bug, aims provide schoolchildren with knowledge of prudent antibiotic use how reduce spread infection. Many schools approach learning in different ways; therefore, it is essential research school needs variety styles when creating any resources. This article outlines process involved during development a pan-European educational resource,...
e-Bug is a pan-European antibiotic and hygiene teaching resource that aims to reinforce awareness in school children of microbes, prudent use, the transmission infection. Prior production resource, it was essential examine educational structure across each partner country assess what were being taught on these topics. A questionnaire devised for distribution European (Belgium, Czech Republic, Denmark, England, France, Greece, Italy, Poland, Portugal Spain), exploring their examining...
To test four 16-membered macrolides (josamycin, spiramycin, midecamycin and rokitamycin) along with other compounds in the same class (erythromycin, clarithromycin, roxithromycin azithromycin) plus clindamycin telithromycin, against Streptococcus pyogenes pneumoniae isolates well-characterized resistance genotypes.Four hundred eighty-six of S. 375 were assayed for their macrolide susceptibilities investigated by PCR to detect different erythromycin genes. All strains had been isolated over...
One third of coronavirus disease 2019 (COVID-19) patients have gastrointestinal symptoms. Severe acute respiratory syndrome 2 (SARS-CoV-2) RNA has been detected in stool samples approximately 50% COVID-19 individuals. Fecal calprotectin is a marker inflammation the general population.To investigate if fecal correlates with SARS-CoV-2 intestinal shedding pneumonia.Patients pneumonia admitted to Infectious Disease Unit (University Hospital Trieste, Italy) from September November 2020 were...
A total of 78 isolates Pseudomonas aeruginosa grouped according to the phenotype for ceftazidime and imipenem susceptibility/resistance were used assess accuracy Vitek 2 system in antimicrobial susceptibility testing. Comparisons made with a MIC gradient test piperacillin-tazobactam, ceftazidime, aztreonam, imipenem, meropenem, gentamicin, ciprofloxacin. For 546 isolate-antimicrobial combinations tested, category agreement was 83.6%, 2.0, 1.6, 12.8% very major, minor errors, respectively....
Neurogenin3 is a member of the basic helix-loop-helix ('bHLH') family transcription factors. It plays crucial role in commitment embryonic endoderm into pancreatic differentiation programme. This factor considered to act upstream cascade other factors, leading fully differentiated endocrine phenotype. Direct observation sequential activation these factors starting from had never been demonstrated. By using retinoic acid-derived-endoderm F9 cells as model, present study indicates that ectopic...
We aimed to assess the combined role of vitamin D and albumin serum levels as predictors COVID-19 disease progression.We conducted a prospective observational study on adult patients hospitalized for SARS-CoV-2 pneumonia (March-September 2020). Vitamin were measured admission. These variables categorized in < 3.5 or ≥ g/dL 30 ng/mL ng/mL. excluded with known bone diseases, renal failure, hypercalcemia and/or treated antiepileptic drugs steroids, who received previous supplementation. A...
Post-coronavirus disease 2019 (post-COVID-19) condition, previously referred to as long COVID, includes a post-acute syndrome defined by the presence of non-specific symptoms occurring usually 3 months from onset acute phase and lasting at least 2 months. Patients with chronic lymphocytic leukemia (CLL) represent high-risk population for COVID-19. Moreover, response SARS-CoV-2 vaccination is often absent or inadequate. The introduction monoclonal antibodies (mAbs) in treatment landscape...
ABSTRACT A Klebsiella pneumoniae strain resistant to third-generation cephalosporins was isolated in the eastern Netherlands. The found carry a novel extended-spectrum β-lactamase, namely, SHV-31. combination of two mutations by which SHV-31 differs from SHV-1, L35Q and E240K, had previously only been described association with one or more additional mutations.
687 isolates of Streptococcus pyogenes and 600 pneumoniae, isolated over the period 2002-2003 from specimens different human origin obtained in 16 Italian centres, were assayed for their susceptibilities to macrolides telithromycin, investigated by PCR detect erythromycin resistance genes. 25.5% S. proved resistant erythromycin, as well clarithromycin azithromycin. 6.6% non-susceptible clindamycin. 4.9% telithromycin. 22.3% all erythromycin-resistant exhibited cMLSB resistance, 50.3% iMLSB...
Web server log analysis is being increasingly used to evaluate the user behaviour on healthcare resource web sites due detailed record of activity that they contain. This study aimed use this information e-Bug site, a provides range educational resources about microbes, hand and respiratory hygiene, antibiotics. evaluation was conducted by analysing logs site for period January 2008 November 2009, using proprietary application named Sawmill. The has had >900 000 page views generated from >88...