- Genital Health and Disease
- Urologic and reproductive health conditions
- Cancer and Skin Lesions
- Health and Medical Research Impacts
- Hidradenitis Suppurativa and Treatments
- Urological Disorders and Treatments
- Autoimmune Bullous Skin Diseases
- Dermatology and Skin Diseases
- Oral Health Pathology and Treatment
- Innovations in Medical Education
- Skin Protection and Aging
- Nail Diseases and Treatments
- Contact Dermatitis and Allergies
- Psoriasis: Treatment and Pathogenesis
- Dermatological diseases and infestations
- Chemotherapy-related skin toxicity
- Primary Care and Health Outcomes
- Colorectal and Anal Carcinomas
- Autoimmune and Inflammatory Disorders
- Acne and Rosacea Treatments and Effects
- Connexins and lens biology
- Diverse Approaches in Healthcare and Education Studies
- Education and Learning Interventions
- Medicine and Dermatology Studies History
- Health Systems, Economic Evaluations, Quality of Life
St Vincent's Hospital
2015-2025
Royal Women's Hospital
2016-2024
St. Vincent's Hospital
2024
Saint Vincent's Catholic Medical Center
2024
St. Vincent's Birmingham
2024
Royal Children's Hospital
2022
Western Health
2022
The University of Melbourne
2022
Royal Australian College of General Practitioners
2022
Skin Health Institute
2021
Bullous pemphigoid is a blistering skin disorder with increased mortality. We tested whether strategy of starting treatment doxycycline gives acceptable short-term blister control while conferring long-term safety advantages over oral corticosteroids.We did pragmatic, multicentre, parallel-group randomised controlled trial adults bullous (three or more blisters at two sites and linear basement membrane IgG C3). Participants were randomly assigned to (200 mg per day) prednisolone (0·5 mg/kg...
Abstract Objective To determine how many specialist trainees are required to conduct research projects, they these studies, and their views on the value of activities; assess design reporting quality reports. Study Online, anonymous survey. Setting, participants Current recent (past five years) at Australian New Zealand colleges, recruited through eleven colleges snowballing; survey was available 31 March – December 2021. Main outcome measures Whether were as part specialty training;...
Abstract Background/Objectives The Vulval disease Quality of Life Index (VQLI) is a new tool that assesses the burden vulval on quality life (QoL). Our objective was to assess correlation between VQLI score and clinician‐rated severity scores, overall patient itch/discomfort, duration, sexual activity, age, in lichen sclerosus (VLS) at disorders clinic. Methods A retrospective case note review, including consecutive women with VLS who attended clinic April October 2018. Outcome measures...
Journal Article A novel missense mutation in GJB2, p.Tyr65His, causes severe Vohwinkel syndrome Get access E.A. de Zwart‐Storm, Zwart‐Storm Department of DermatologyGROW – School for Oncology and Developmental Biology, Maastricht University Medical Center, PO Box 5800, 6202 AZ Maastricht, the NetherlandsDepartment Biological Biomedical Sciences, Glasgow Caledonian University, Glasgow, U.K. Correspondence: Eugene A. Zwart‐Storm. E‐mail: ea.de.zwart.storm@mumc.nl Search other works by this...
Vulval lichen sclerosus (VLS) is a chronic inflammatory skin condition predominantly affecting the anogenital region in women and children. To date, there lack of agreement amongst experts on severity scale to aid assessment, research treatment stratification VLS. Furthermore, literature best practice for long-term management VLS lacking. The aim this consensus provide broad guidelines short VLS.An initial focus group Australasian vulval dermatology developed draft statement Based results...
We report a case of actinic folliculitis in 29-year-old woman who presented with 10-year history recurrent pustular eruption affecting her face, typically appearing 4-6 h after exposure to sunlight. Actinic follicuitis is rare photodermatosis, which falls into the same spectrum as acne aestivalis and superficial folliculitis.
A core outcome set (COS) is an agreed minimum of outcomes that should be measured globally in all clinical trials or other specified settings, such as routine practice quality assurance, for a particular condition.1 COS consists primarily domains (what to measure) and eventually measurement instruments (how measure). The universal uptake suitable critical advancing patient-centred care reducing research waste, through enabling comparative effectiveness limiting reporting bias.2, 3...
Abstract Objective To explore medical trainees’ experiences and views concerning college-mandated research projects. Setting Online survey (Apr-Dec 2021) of current recent past trainees Australian New Zealand colleges recruited through 11 principal snowballing. Participants Current trainee or completed training in the 5 years. Main outcome measures We asked participants: whether they were required to conduct as part their college training, how conducted research, activity after training....
Abstract Objectives It is common practice to advise people with vulvar lichen sclerosus perform self-examination (VSE) optimize topical therapy and detect changes that may represent active disease, scarring, and/or squamous cell carcinoma development. The aim of this study was better understand people's willingness potential barriers performing VSE. Materials Method A cross-sectional survey undertaken all patients LS presenting a tertiary referral dermatology clinic in Australia, from June...
This case series aims to evaluate the demographic features, disease characteristics, and treatment outcomes of 8 patients receiving subcutaneous (SC) adalimumab for severe, refractory vulval lichen sclerosus (VLS) and/or planus (VLP). Both conditions are chronic inflammatory dermatoses that significantly impair quality life, although first-line typically involves potent ultrapotent topical corticosteroids, managing severe cases is challenging due a lack FDA-approved systemic therapies....
We report a case of 69-year-old woman with mycosis fungoides (MF), who presented clinical and histological features cutaneous lupus, for 6 years was treated this, until repeated biopsies gene-rearrangement studies confirmed diagnosis MF. In addition, she developed thromboemboli found to have lupus anticoagulant antibodies. The possible biological relationship between antiphospholipid antibody syndrome MF is considered. To our knowledge, this the first reported masquerading as lupus.
Objectives Plasma cell vulvitis (PCV) is a rare inflammatory vulvar condition. The aim of this study was to describe the natural history, treatment, impact on quality life, and factors associated with poorer outcomes for PCV. Methods A mixed-methods approach used combining retrospective case note review cross-sectional telephone questionnaire. All women diagnosed PCV attending disorders clinic at Royal Women's Hospital between January 2011 December 2020 were included. Results During 10-year...
Benign familial pemphigus, also known as Hailey–Hailey disease (HHD), is a rare autosomal-dominant genetic skin disorder characterized by symmetrical, well-demarcated, erythematous, painful erosive and crusted plaques in the intertrigous regions. Treatment options are limited aimed at control limiting complications. Ocrelizumab, an anti-CD20 antibody, was given to treat our patient’s multiple sclerosis, incidentally found have cleared her HHD, thus offering potential effective treatment option.
Vulval Lichen Sclerosus (VLS) is a chronic inflammatory dermatosis that significantly impacts the quality of life. We report 2 cases severe treatment-resistant VLS treated with subcutaneous adalimumab. One patient showed modest clinical improvement no significant in quality-of-life measures. The second both and Both patients achieved optimal control maintenance dosing 40 mg subcutaneously weekly. Adalimumab may be treatment option for recalcitrant VLS; however, trials are required to confirm...