A5104149274- Vascular Malformations and Hemangiomas
- Vascular Malformations Diagnosis and Treatment
- Parvovirus B19 Infection Studies
- Central Venous Catheters and Hemodialysis
- Tumors and Oncological Cases
- Genetic and rare skin diseases.
- Organometallic Compounds Synthesis and Characterization
- Neonatal Respiratory Health Research
- Neuroscience of respiration and sleep
- Crystal structures of chemical compounds
- Cystic Fibrosis Research Advances
- Crystallography and molecular interactions
- Nail Diseases and Treatments
- Autoimmune and Inflammatory Disorders
- Vascular Tumors and Angiosarcomas
- Vascular anomalies and interventions
- Streptococcal Infections and Treatments
- Child Nutrition and Feeding Issues
- Restraint-Related Deaths
- Congenital Ear and Nasal Anomalies
- Oral Health Pathology and Treatment
- Histiocytic Disorders and Treatments
- Neurosurgical Procedures and Complications
- Skin and Cellular Biology Research
- Fluorine in Organic Chemistry
Royal Children's Hospital
2012-2025
Monash University
1981-2023
Murdoch Children's Research Institute
2013-2023
Yahoo (United Kingdom)
2023
Monash Medical Centre
2018-2022
The University of Melbourne
2017-2018
Australian Regenerative Medicine Institute
2013
Schneider Children's Hospital
2006
University of British Columbia
2006
Yale University
2006
Oral propranolol has been used to treat complicated infantile hemangiomas, although data from randomized, controlled trials inform its use are limited.
Although most infantile haemangiomas do not require treatment due to a natural history of spontaneous involution, some early intervention. The Australasian Vascular Anomalies Network and the Paediatric Dermatology have developed consensus statement for with oral propranolol. Infants that are life threatening, at risk ulceration, or causing significant functional impairment, psychological impact physical deformity should be treated Oral propranolol is safe effective in healthy infants can...
Abstract Background Capillary lymphatic venous malformations (CLVM) and associated syndromes, including Klippel–Trenaunay syndrome (KTS) congenital lipomatous overgrowth, vascular malformation, epidermal nevi, skeletal, spinal (CLOVES), are underrecognized disorders with high morbidity from chronic pain, recurrent infections, bleeding, clotting complications. The rarity of these heterogeneity clinical presentations make large‐scale randomized drug trials challenging. Identification PIK3CA...
Propranolol has recently emerged as an effective drug treatment for infantile haemangiomas. The side effect profile of the and safety administering propranolol in outpatient settings this age group remain uncertain. We report our experience with 200 infants children prescribed to treat haemangiomas, including 37 patients considered have a poor response treatment.Patients were (1 mg/kg/dose bd) outpatients at Vascular Anomalies Service Royal Children's Hospital, Melbourne.The median...
ABSTRACT Background Medical teaching has always emphasized the importance of a good history and complete medical examination. Missing some areas examination can lead to errors in diagnosis management adverse outcomes. At same time, factors including time pressures, medicolegal concerns, desire avoid embarrassment for patients have led many practitioners routinely bypassing genital and/or breast Methods This study is prospective audit findings attending their first appointment at consultant...
Abstract: We report four infants born with necrotic caput succedaneum that led to a scarring alopecia ongoing inflammation and persistent scale–crust. These lesions did not significantly improve topical or oral antibiotics, but respond somewhat corticosteroids. Alopecia chronic erosive scale–crust moderate response corticosteroids are findings consistent diagnosis of pustular dermatosis the scalp.
Background: Keratosis pilaris is a common skin disorder of childhood that often improves with age.Less variants keratosis include atrophicans and atrophodermia vermiculata.Observations: In this case series from dermatology practices in the United States, Canada, Israel, Australia, clinical characteristics 27 patients rubra are described.Marked erythema follicular prominence was noted all patients, most commonly affecting lateral aspects cheeks proximal arms legs, both more marked widespread...
Objectives To compare the frequency of headache and procedure time following lumbar puncture (LP) using a 25-gauge needle compared to 22-gauge needle. Design 4-period crossover blinded randomised controlled trial. Setting Oncology unit, Royal Children's Hospital, Melbourne. Patients Children aged 4–15 years at enrolment having LPs as part their treatment for leukaemia. Interventions Each child was allocated random sequence four LPs, two with Outcome measures The presence post-LP headache....
Aim To describe the clinical and histopathological characteristics of infantile haemangiomas that failed treatment with oral propranolol . Design This study is a case series from vascular birthmarks clinic at R oyal C hildren's H ospital, M elbourne. Patients The patients for this were infants who commenced before 6 months age treated least 4 without satisfactory result. For histology immunohistochemistry, tissue four non‐responding subsequently underwent surgical excision was matched...
Vulval lichen sclerosus (VLS) is a chronic inflammatory skin condition predominantly affecting the anogenital region in women and children. To date, there lack of agreement amongst experts on severity scale to aid assessment, research treatment stratification VLS. Furthermore, literature best practice for long-term management VLS lacking. The aim this consensus provide broad guidelines short VLS.An initial focus group Australasian vulval dermatology developed draft statement Based results...
Objectives: To estimate the prevalence of vascular malformations using retrospective data collected from 1999 to 2020 in a specialty anomalies service. Methods: The service associated with Royal Children’s Hospital provides reference both adults and children, covering entire state Victoria, Australia, which has population 6.7 million around 70,000 births per year. A database patients was interrogated identify those treated by over study period diagnosis malformation, excluding capillary...
Abstract Haemangioma of infancy, a benign tumour blood vessels, is the most common infancy. Ulceration, complication, presents unique wound care challenge. A retrospective audit medical records children with haemangioma infancy who presented to Royal Children's Hospital, Melbourne, Australia, between January 2000 and December 2014 was undertaken an aim examine management ulcerated In total, 535 hospital were identified as suitable, which 352 randomly selected audited, 84 patients had 62...
Propranolol is first-line systemic therapy for infantile hemangiomas. Its use in infants has significantly increased the last decade. It a good safety profile, but there are concerns about side effects. We present 5 unexplained deaths of who were on propranolol treatment