Tarun Chakravarty
A5076977377- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Aortic Disease and Treatment Approaches
- Coronary Interventions and Diagnostics
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Venous Thromboembolism Diagnosis and Management
- Tissue Engineering and Regenerative Medicine
- Mechanical Circulatory Support Devices
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Electrospun Nanofibers in Biomedical Applications
- Congenital heart defects research
- Pulmonary Hypertension Research and Treatments
- Congenital Heart Disease Studies
- Antimicrobial Resistance in Staphylococcus
- Advanced X-ray and CT Imaging
- Cardiac Fibrosis and Remodeling
- Aortic aneurysm repair treatments
- Mesenchymal stem cell research
Cedars-Sinai Medical Center
2016-2025
Cedars-Sinai Smidt Heart Institute
2016-2025
Rabin Medical Center
2024
Sinai Hospital
2020
Cardiovascular Research Foundation
2019
Duke Medical Center
2017
Heart Hospital Baylor Plano
2015-2017
Clinical Research Institute
2017
Duke University Hospital
2017
Memorial Hermann
2017
Transcatheter aortic valve replacement (TAVR) is being increasingly performed in patients with bicuspid stenosis (AS).This study sought to compare the procedural and clinical outcomes versus tricuspid AS from Bicuspid TAVR multicenter registry.Outcomes of 561 4,546 were compared after propensity score matching, assembling 546 pairs similar baseline characteristics. Procedural recorded according Valve Academic Research Consortium-2 criteria.Compared AS, had more frequent conversion surgery...
We sought to evaluate the outcomes of transcatheter mitral valve replacement (TMVR) for patients with degenerated bioprostheses [valve-in-valve (ViV)], failed annuloplasty rings [valve-in-ring (ViR)], and severe annular calcification [valve-in-mitral (ViMAC)].From TMVR multicentre registry, procedural clinical ViV, ViR, ViMAC were compared according Mitral Valve Academic Research Consortium (MVARC) criteria. A total 521 mean Society Thoracic Surgeons score 9.0 ± 7.0% underwent (322 141 58...
Cardiosphere-derived cells (CDCs) are an attractive cell type for tissue regeneration, and autologous CDCs being tested clinically. However, therapy necessitates patient-specific harvesting processing, with delays to possible variations in potency. The use of allogeneic CDCs, if safe effective, would obviate such limitations. We compared syngeneic CDC transplantation rats from immunologically-mismatched inbred strains.In vitro, expressed major histocompatibility complex class I but not II...
Transcatheter aortic valve replacement (TAVR) indications are expanding, leading to an increasing number of patients with bicuspid stenosis undergoing TAVR. Pivotal randomized trials conducted obtain US Food and Drug Administration approval excluded anatomy.To compare the outcomes TAVR a balloon-expandable for vs tricuspid stenosis.Registry-based prospective cohort study at 552 centers. Participants were enrolled in Society Thoracic Surgeons (STS)/American College Cardiology (ACC) Valve...
Subclinical leaflet thrombosis, characterized by hypoattenuated thickening (HALT) and reduced motion observed on 4-dimensional computed tomography (CT), may represent a form of bioprosthetic valve dysfunction. The U.S. Food Drug Administration mandated CT studies to understand the natural history this finding, differences between transcatheter surgical valves, its association with hemodynamics clinical outcomes. PARTNER 3 (The Safety Effectiveness SAPIEN Transcatheter Heart Valve in Low-Risk...
Four-dimensional volume-rendered computed tomography (4DCT) has demonstrated instances of hypo-attenuating leaflet thickening (HALT) with or without hypo-attenuation affecting motion (HAM) after transcatheter and surgical aortic valve implantation (TAVI, SAVR). The temporal pattern evolution these phenomena is uncertain.The SAVORY registry enrolled patients treated by TAVI (n = 75) SAVR 30) two 4DCT scans fully interpretable for HALT HAM as well unchanged anti-thrombotic medication between...
For patients with symptomatic, severe tricuspid regurgitation (TR), early results of transcatheter valve (TV) intervention studies have shown significant improvements in functional status and quality life associated right-heart reverse remodelling. Longer-term follow-up is needed to confirm sustained these outcomes.
Importance There are limited data on the outcomes of transcatheter edge-to-edge mitral valve repair for degenerative regurgitation (MR) in a real-world setting. Objective To evaluate MR. Design, Setting, and Participants Cohort study consecutive patients Society Thoracic Surgeons/American College Cardiology Transcatheter Valve Therapies Registry who underwent nonemergent MR US from 2014 through 2022. Exposure with MitraClip device (Abbott). Main Outcomes Measures The primary end point was...
AimsWe sought to optimize a method for quantification of the calcium in aortic-valvar complex prediction significant paravalvular leak (PVL) after transcatheter aortic valve implantation (TAVI).