A5031123712- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Infective Endocarditis Diagnosis and Management
- Venous Thromboembolism Diagnosis and Management
- Cardiac Health and Mental Health
- Aortic Disease and Treatment Approaches
- Peripheral Artery Disease Management
- Atrial Fibrillation Management and Outcomes
- Vascular Procedures and Complications
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Structural Anomalies and Repair
- Aortic aneurysm repair treatments
- Cardiomyopathy and Myosin Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Lipoproteins and Cardiovascular Health
- Cardiovascular Effects of Exercise
- Cardiac Arrhythmias and Treatments
- Central Venous Catheters and Hemodialysis
- Cardiac tumors and thrombi
- Cardiovascular Function and Risk Factors
- Renal and Vascular Pathologies
- Heart Failure Treatment and Management
Instituto Cardiovascular de Buenos Aires
2011-2024
Universidade de São Paulo
2021
Florida College
2011
VA Boston Healthcare System
2011
Brigham and Women's Hospital
2011
Harefield Hospital
2011
Thrombolysis in Myocardial Infarction Study Group
2011
Tokai University
2011
University College Dublin
2011
Jagiellonian University
2011
Intravenous cangrelor, a rapid-acting, reversible adenosine diphosphate (ADP) receptor antagonist, might reduce ischemic events during percutaneous coronary intervention (PCI).In this double-blind, placebo-controlled study, we randomly assigned 5362 patients who had not been treated with clopidogrel to receive either cangrelor or placebo at the time of PCI, followed by 600 mg clopidogrel. The primary end point was composite death, myocardial infarction, ischemia-driven revascularization 48...
Thrombin is a key mediator of platelet activation. Atopaxar reversible protease-activated receptor-1 antagonist that interferes with thrombin-mediated effects. The phase II Lessons From Antagonizing the Cellular Effect Thrombin-Coronary Artery Disease (LANCELOT-CAD) trial examined safety and tolerability prolonged therapy atopaxar in subjects CAD.Subjects qualifying history were randomized double-blind fashion to 3 dosing regimens (50, 100, or 200 mg daily) matching placebo for 24 weeks...
Introducción: El acceso radial se ha asociado a numerosos beneficios en angioplastia coronaria comparación con el femoral. Sin embargo, múltiples registros internacionales han reportado una escasa adherencia esta técnica. Objetivos: Evaluar la seguridad, eficacia y eficiencia operativa de según vía utilizada cuadro clínico del paciente. Métodos:Análisis registro,unicéntrico retrospectivo los pacientes enfermedad tratados desde marzo 2009 junio 2018,según vascular.Se aplicó un modelo...
Background: The safety and efficacy of antithrombotic regimens may differ between patients with atrial fibrillation who have acute coronary syndromes (ACS), treated medically or percutaneous intervention (PCI), those undergoing elective PCI. Methods: Using a 2×2 factorial design, we compared apixaban vitamin K antagonists aspirin placebo in had ACS were PCI receiving P2Y 12 inhibitor. We explored bleeding, death hospitalization, as well ischemic events, by strategy 3 prespecified subgroups:...
Importance Abbreviated dual antiplatelet therapy (DAPT) reduces bleeding with no increase in ischemic events patients at high risk (HBR) undergoing percutaneous coronary intervention (PCI). Objectives To evaluate the association of sex comparative effectiveness abbreviated vs standard DAPT HBR. Design, Setting, and Patients This prespecified subgroup analysis followed Management High Bleeding Risk Post Bioresorbable Polymer Coated Stent Implantation With an Standard Regimen (MASTER DAPT)...
Previous trials testing stents compared with balloon angioplasty excluded patients complex lesions and did not assess the effect of adjunctive platelet IIb/IIIa inhibition. This analysis sought to stenting abciximab specifically for lesions.Patients (long, tandem, severely calcified, restenotic, thrombotic, or ostial; total occlusions; bifurcations; saphenous vein grafts; multivessel interventions) from Evaluation PTCA Improve Long-Term Outcome by c7E3 GP Receptor Blockade (EPILOG) Platelet...
Objective Cigarette smokers have an unexplained low mortality following ST-segment elevation acute myocardial infarction (STEMI). Our aim was to determine whether the presence of active smoking has a beneficial effect on reperfusion primary percutaneous intervention (PCI). Methods A total 140 STEMI patients treated with PCI were included in analysis. All 24-h monitoring, each analyzed by independent, blinded core laboratory. We divided population according status: (n = 56) and nonactive 84)....
Background No study has evaluated the impact of additional manipulation demanded by multiple resheathing (MR) in patients undergoing transcatheter aortic valve replacement with repositionable self-expanding valves. Methods and Results This included a real-world, multicenter registry involving 16 centers from Canada, Germany, Latin America, Spain. All consecutive who underwent Evolut R, PRO, Portico valves were included. Patients divided according to number resheathing: no resheathing, single...
Inadequate stent implantation is associated with thrombosis and restenosis. StentBoost can enhance visualization evaluate expansion. Currently, there are limited comparison studies between intravascular ultrasound (IVUS). We aimed to test the correlation agreement IVUS measurements. From December 2010 2011, 38 patients (54 stents) were analyzed using StentBoost. Minimal diameter proximal distal edge compared imaging techniques Pearson Bland–Altman scatter plot. There was good measurements...
The aim of this study was to determine whether the presence collateral circulation had a beneficial effect following primary angioplasty. In all, 114 patients who underwent angioplasty were included. Patients with lower basal ST-segment deviation (P = .004), white cell count ( P .001), peak creatine kinase and regional wall motion score values .03) than without circulation. After procedure, group collaterals associated higher rates normal myocardial blush, complete ST resolution, shorter...
INTRODUÇÃO: A magnitude da resolução do supradesnivelamento segmento ST é um marcador de reperfusão miocárdica em pacientes com infarto agudo miocárdio. incompleta foi identificada como preditor resultados desfavoráveis miocárdio após terapia reperfusão. Este estudo teve objetivos descrever a frequência registro contemporâneo submetidos angioplastia primária e fazer uma comparação seus hospitalares que apresentaram completa ST. MÉTODO: Entre julho 2008 fevereiro 2009, foram incluídos 183...
Nonagenarians are mostly denied from different therapeutic strategies due to high preoperative risk. We present the results of nonagenarians with severe aortic stenosis (AS) undergoing transcatheter valve replacement (TAVR).Our retrospective analysis include baseline and procedural data along clinical outcome. Clinical follow-up was performed in all patients after TAVR.Out 689 patients, 33 a mean age 90.9±1.4years suffering AS elevated comorbidity index (logistic EuroSCORE 16.3±9.6%, STS...