A5060888059- Bayesian Methods and Mixture Models
- Statistical Methods and Inference
- Statistical Methods and Bayesian Inference
- Air Quality and Health Impacts
- Cerebral Palsy and Movement Disorders
- Bayesian Modeling and Causal Inference
- Health disparities and outcomes
- Spatial and Panel Data Analysis
- Gene expression and cancer classification
- Climate Change and Health Impacts
- Environmental Justice and Health Disparities
- Data-Driven Disease Surveillance
- Advanced Clustering Algorithms Research
- Private Equity and Venture Capital
- Infant Development and Preterm Care
- Nutritional Studies and Diet
- Firm Innovation and Growth
- Family and Disability Support Research
- Data Management and Algorithms
- Entrepreneurship Studies and Influences
- Economic and Environmental Valuation
- Health Systems, Economic Evaluations, Quality of Life
- Urban Transport and Accessibility
- Food Security and Health in Diverse Populations
- Obesity, Physical Activity, Diet
Queen Mary University of London
2018-2025
British Library
2019-2024
Turing Institute
2019-2024
The Alan Turing Institute
2019-2024
Wollo University
2022
University of Gondar
2022
McMaster University
2022
Universidad de Navarra
2021
University of Michigan
2019-2021
Michigan United
2021
Twenty-nine teams involving 61 analysts used the same data set to address research question: whether soccer referees are more likely give red cards dark-skin-toned players than light-skin-toned players. Analytic approaches varied widely across teams, and estimated effect sizes ranged from 0.89 2.93 ( Mdn = 1.31) in odds-ratio units. Twenty (69%) found a statistically significant positive effect, 9 (31%) did not observe relationship. Overall, 29 different analyses 21 unique combinations of...
Cerebral palsy (CP) is considered a pediatric condition despite most individuals with CP living into adulthood. Thus, there lack of evidence in adults CP, which includes paucity research examining mental health this population.To determine the risk depression and anxiety compared an age-, sex-, practice-matched reference group without using primary care data.Retrospective longitudinal cohort study set UK care. Data were analyzed Cox proportional hazards regression analyses adjusted for...
PReMiuM is a recently developed R package for Bayesian clustering using Dirichlet process mixture model. This model an alternative to regression models, non- parametrically linking response vector covariate data through cluster membership (Molitor, Papathomas, Jerrett, and Richardson 2010). The allows binary, categorical, count continuous response, as well discrete covariates. Additionally, predictions may be made the missing values covariates are handled. Several samplers label switching...
Abstract Background Picoeukaryotes represent an important, yet poorly characterized component of marine phytoplankton. The recent genome availability for two species Ostreococcus and Micromonas has led to the emergence picophytoplankton comparative genomics. Sequencing revealed many unexpected features about structure several hypotheses on biology physiology. Despite accumulation genomic data, little is known gene expression in eukaryotic picophytoplankton. Results We have conducted a...
To compare mortality rates for cardiovascular disease, cancer, and respiratory disease between adults with cerebral palsy (CP) the general population.A cohort study was conducted using data from CP in England, identified through a primary care set (the Clinical Practice Research Datalink), linked on death registrations Office National Statistics. Cause of categorized according to International Classification Diseases codes. Standardized ratios (SMRs) were calculated population, adjusted age,...
Research indicates that multiple outdoor air pollutants and adverse neighborhood conditions are spatially correlated. Yet health risks associated with concurrent exposure to pollution mixtures clustered factors remain underexplored. Statistical models assess the effects from pollutant limited, due problems of collinearity between area-level covariates, increases in covariate dimensionality. Here we identify profiles contextual within Los Angeles (LA) County. We then relate these term low...
Twenty-nine teams involving 61 analysts used the same dataset to address research question: whether soccer referees are more likely give red cards dark skin toned players than light players. Analytic approaches varied widely across teams, and estimated effect sizes ranged from 0.89 2.93 in odds ratio units, with a median of 1.31. Twenty (69%) found statistically significant positive nine (31%) observed non-significant relationship. Overall 29 different analyses 21 unique combinations...
Air pollution epidemiological studies suggest that elevated exposure to fine particulate matter (PM2.5) is associated with higher prevalence of term low birth weight (TLBW). Previous have generally assumed the exposure-response PM2.5 on TLBW be same throughout a large geographical area. Health effects related exposures, however, may not uniformly distributed spatially, creating need for explicitly investigate spatial distribution relationship between individual-level and TLBW. Here, we...
Abstract By drawing on large-scale online data we are able to construct and analyze the time-varying worldwide network of professional relationships among start-ups. The nodes this represent companies, while links model flow employees associated transfer know-how across companies. We use centrality measures assess, at an early stage, likelihood long-term positive economic performance a start-up. find that start-up has predictive power by using can provide valuable recommendations, sometimes...
We consider the question of Markov chain Monte Carlo sampling from a general stick-breaking Dirichlet process mixture model, with concentration parameter [Formula: see text]. This paper introduces Gibbs algorithm that combines slice approach Walker (Communications in Statistics - Simulation and Computation 36:45-54, 2007) retrospective Papaspiliopoulos Roberts (Biometrika 95(1):169-186, 2008). Our is implemented as efficient open source C++ software, available an R package, based on blocking...
Airborne particles are a complex mix of organic and inorganic compounds, with range physical chemical properties. Estimation how simultaneous exposure to air affects the risk adverse health response represents challenge for scientific research quality management. In this paper, we present Bayesian approach that can tackle problem within framework time series analysis.We used Dirichlet process mixture models cluster points similar multipollutant profiles, while adjusting seasonal cycles,...
Summary The paper investigates the dependences between levels of severity road traffic accidents, accounting at same time for spatial and temporal correlations. study analyses accidents data ward level in England over period 2005–2013. We include our model multivariate spatially structured unstructured effects to capture severities, within a Bayesian hierarchical formulation. also component we carry out an extensive comparison. results show important associations both downward trend is...
To compare the incidence of noncommunicable diseases between adults with and without cerebral palsy (CP).A cohort study was conducted using primary care data from Clinical Practice Research Datalink. Cox models, stratified by matched set adjusted for potential confounders, were fitted to risk any disease, cancer, cardiovascular type 2 diabetes mellitus, respiratory disease CP.The analysis included 1,705 CP 5,115 age-, sex-, general practice-matched CP. There evidence analyses that had 75%...
People with cerebral palsy (CP) may be at increased risk of musculoskeletal conditions due to various factors including malnutrition and abnormal levels skeletal loading. This study aimed compare the incidence osteoporosis, osteoarthritis inflammatory diseases between adults without CP.A population based cohort was conducted using data from Clinical Practice Research Datalink collected 1987 2015. Adults CP were matched for age, sex general practice. Cox models, stratified by set adjusted...
The picoeukaryotic alga Ostreococcus tauri (Chlorophyta) belongs to the widespread group of marine prasinophytes. Despite its ecological importance, little is known about metabolism this alga.In work, changes in metabolome were quantified when O. was grown under alternating cycles 12 h light and darkness.Algal analyzed by gas chromatography-mass spectrometry. Using fluorescence-activated cell sorting, bacteria associated with depleted below 0.1% total cells at time metabolic profiling.Of 111...
IntroductionHousehold overcrowding is an important determinant of health and associated with adverse child health, educational social outcomes. ObjectivesWe aimed to determine whether households dependent children were more likely be overcrowded after taking into account household ethnicity housing tenure in urban, ethnically diverse, disadvantaged London population by pseudonymously linking property data. MethodsWe used pseudonymised Unique Property Reference Numbers link electronic records...
Household overcrowding is an important determinant of health and associated with adverse child health, educational social outcomes. We aimed to determine whether households dependent children were more likely be overcrowded after taking into account household ethnicity housing tenure in urban, ethnically diverse, disadvantaged London population by pseudonymously linking property data. used pseudonymised Unique Property Reference Numbers link electronic records Energy Performance Certificate...
In this work we present a statistical approach to distinguish and interpret the complex relationship between several predictors response variable at small area level, in presence of (i) high correlation (ii) spatial for response. Covariates which are highly correlated create collinearity problems when used standard multiple regression model. Many methods have been proposed literature address issue. A very common is an index aggregates all variables interest. For example, it well known that...
Abstract Trees are carbon dioxide sinks and major producers of terrestrial biomass with distinct seasonal growth patterns. Circadian clocks enable the coordination physiological biochemical temporal activities, optimally regulating multiple traits including growth. To dissect clock's role in growth, we analysed Populus tremula × P. tremuloides trees impaired clock function due to down‐regulation central components. late elongated hypocotyl ( lhy‐10 ) trees, which expression LHY1 LHY2 is...
Abstract Background A common characteristic of environmental epidemiology is the multi-dimensional aspect exposure patterns, frequently reduced to a cumulative for simplicity analysis. By adopting flexible Bayesian clustering approach, we explore risk function linking history disease. This approach applied here study relationship between different smoking characteristics and lung cancer in framework population based case control study. Methods Our includes 4658 males (1995 cases, 2663...
<h3>Background</h3> The association between lung cancer and occupational exposure to organic solvents is discussed. Since different are often used <i>simultaneously</i>, it difficult assess the role of individual substances. <h3>Objectives</h3> present study focused on an in-depth investigation potential risk a large group solvents, taking into account well-known factors for cancer, tobacco smoking asbestos. <h3>Methods</h3> We analysed data from Investigation environmental causes...
To investigate long-term associations between metal components of particulate matter (PM) and mortality lung cancer incidence.Small area (ecological) study.Population living in all wards (~9000 individuals per ward) the London Oxford England, comprising 13.6 million individuals.We used land use regression models originally Transport related Air Pollution Health Impacts-Integrated Methodologies for Assessing Particulate Matter study to estimate exposure copper, iron zinc ambient air PM. We...