- Bone Tissue Engineering Materials
- Semiconductor materials and devices
- Electrospun Nanofibers in Biomedical Applications
- Advancements in Semiconductor Devices and Circuit Design
- Periodontal Regeneration and Treatments
- Orthopaedic implants and arthroplasty
- Dental Implant Techniques and Outcomes
- Silicon Carbide Semiconductor Technologies
- 3D Printing in Biomedical Research
- Hydrogels: synthesis, properties, applications
- Polymer Surface Interaction Studies
- Surface Modification and Superhydrophobicity
- Graphene and Nanomaterials Applications
- Tissue Engineering and Regenerative Medicine
- Adhesion, Friction, and Surface Interactions
- Thin-Film Transistor Technologies
- Nanoparticle-Based Drug Delivery
- Bone Metabolism and Diseases
- Wound Healing and Treatments
- ZnO doping and properties
- Electrohydrodynamics and Fluid Dynamics
- biodegradable polymer synthesis and properties
- Bone health and treatments
- Nanoparticles: synthesis and applications
- Additive Manufacturing and 3D Printing Technologies
Chungnam National University
2023-2024
Yonsei University
2016-2021
Korea Institute of Industrial Technology
2018
Kyung Hee University
2008-2016
University of Washington
2015-2016
Gold nanoparticles (GNPs) are widely used in diagnostics, drug delivery, biomedical imaging, and photo-thermal therapy due to their surface plasmon resonance, fluorescence, easy-surface functionalization. According recent studies, GNPs display a positive effect on the osteogenic differentiation of mesenchymal stem cells (MSCs) MC3T3-E1 osteoblast-like cells. The aim this study was develop new approach for bone tissue regeneration based utilization biodegradable hydrogel loaded with GNPs. We...
A significant problem that affects tissue-engineered electrospun nanofibrous scaffolds is poor infiltration of cells into the three-dimensional (3D) structure. Physical manipulation can enhance cellular scaffolds. The porosity nanofibers was highly enlarged by ultrasonication in an aqueous solution. and related property changes on a series were observed to be dependent time energy. To evaluate cell scaffold, fibroblasts seeded onto these cultured for different lengths time. penetration...
Gold nanoparticles (GNPs) have been previously reported to inhibit osteoclast (OC) formation. However, previous research only confirmed the osteoclastogenesis inhibitory effect under in vitro conditions. The aim of this study was develop a therapeutic agent for osteoporosis based on utilization GNPs and confirm their both vivo. We prepared β-cyclodextrin (CD) conjugated (CGNPs), which can form inclusion complexes with curcumin (CUR–CGNPs), used these investigate effects receptor activator...
Despite the fact that advances of burn treatment have led to reduction in morbidity caused by burns, infection is still a serious problem. In this study, we designed blended synthetic and natural polymers nanofiber scaffolds using polyurethane (PU) gelatin, which were prepared an electrospinning method. Silver-sulfadiazine (SSD) was co-mixed polymer solution for being incorporated into nanofibers after electrospinning, followed examination burn-wound healing effect. The containing SSD should...
Electrospun chitosan (CTS) nanofibers have been well known for use as a wound dressing in the biomedical field. Nevertheless, fatal bacterial infections are still serious problem when CTS used treatment. In this study, we designed novel based on blending with polyurethane (CTS/PU) containing silver sulfadiazine (AgSD) order to enhance both antibacterial activity and mechanical strength. This fiber sheet was produced using electrospinning (ELSP) technique. The CTS/PU AgSD characterized by...
Recently, the application of nanostructured materials in field tissue engineering has garnered attention to mediate treatment and regeneration bone defects. In this study, poly( l ‐lactic acid) (PLLA)/gelatin (PG) fibrous scaffolds are fabricated β‐cyclodextrin (βCD) grafted nano‐hydroxyapatite (HAp) is coated onto scaffold surface via an interaction between βCD adamantane. Simvastatin (SIM), which known promote osteoblast viability differentiation, loaded into remaining βCD. The specimen...
Poly (L-lactic acid) (PLLA), a biodegradable and biocompatible polyester, has been used as material of for tissue engineered scaffold regenerative medicine. In this study, hydroxyapatite (HAp) PLLA composite was electrospun. fibers were treated with an amino groups containing base in order to fabricate modified polymeric microcylinders. Simvastatin loaded into the PLLA/HAp Our study focuses on incorporation HAp fibrous cylindrical structure, its effects loading release simvastatin,...
In this study, we developed poly(ɛ-caprolactone) (PCL) 3D scaffolds using a solid free form fabrication (SFF) technique. β-cyclodextrin (βCD) was grafted to hydroxyapatite (HAp) and βCD HAp coated onto the PCL scaffold surface, followed by drug loading through an inclusion complex interaction between adamantane (AD) or simvastatin (SIM). The structure characterized scanning electron microscopy (SEM). release profile of in β-CD also evaluated. Osteogenic differentiation adipose-derived...