A5032174070- Silk-based biomaterials and applications
- Tissue Engineering and Regenerative Medicine
- Viral Infectious Diseases and Gene Expression in Insects
- Retinopathy of Prematurity Studies
- Neonatal Respiratory Health Research
- Nerve injury and regeneration
- Silkworms and Sericulture Research
- Electrospun Nanofibers in Biomedical Applications
- Pelvic floor disorders treatments
- Renal and related cancers
- Neonatal and fetal brain pathology
- Urological Disorders and Treatments
- Cancer Research and Treatments
- 3D Printing in Biomedical Research
- Anorectal Disease Treatments and Outcomes
- Cancer, Hypoxia, and Metabolism
- Bladder and Urothelial Cancer Treatments
- Retinal Development and Disorders
- Urinary Bladder and Prostate Research
- Urinary Tract Infections Management
- Neuroscience and Neural Engineering
- Additive Manufacturing and 3D Printing Technologies
- Congenital gastrointestinal and neural anomalies
- Hernia repair and management
Tehran University of Medical Sciences
2021-2025
Children's Medical Center
2021-2025
Islamic Azad University, Tehran
2022
Abstract Despite recent advancements in peripheral nerve regeneration, the creation of conduits with chemical and physical cues to enhance glial cell function support axonal growth remains challenging. This study aimed assess impact electrical stimulation (ES) using a conductive conduit on sciatic regeneration rat model transection injury. The involved fabrication silk fibroin Au nanoparticles (AuNPs). Collagen hydrogel loaded green fluorescent protein (GFP)-positive adipose-derived...
Abstract Background Bladder cancer poses a great burden on society and its high rate of recurrence treatment failure necessitates use appropriate animal models to study pathogenesis test novel treatments. Orthotopic are superior other types since they provide normal microenvironment. Four methods described for developing bladder inside the animal's bladder. Direct intramural injection is one these widely used. However, efficacy in model development has not yet been studied. We aimed evaluate...
Silkworm products were first used by physicians more than 8500 years ago, in the early Neolithic period. In Persian medicine, silkworm extract has several uses for treating and preventing neurological, cardiac, liver diseases. Mature silkworms (Bombyx mori) their pupae contain a variety of growth factors proteins that can be many repair processes, including nerve regeneration.The study aimed to evaluate effects mature mori), on Schwann cell proliferation axon growth.Silkworm extracts...
Retinopathy of prematurity (ROP) is a vasoproliferative disease that alters retinal vascular patterns in preterm neonates with immature vasculature. This study was conducted to investigate the effects cell therapy by bone marrow mononuclear cells (BMMNC) on neurological and damages rat model ROP.Ten newborn Wistar rats were divided randomly into control oxygen-induced retinopathy (OIR) groups. Animals OIR group incubated an oxygen chamber induce retinopathy. One eye animals received BMMNC...
Chronic kidney disease poses a significant threat to public health. Renal replacement therapy is the primary treatment option for end-stage disease. However, there promising and relatively new method in regenerative medicine creating functional organ known as whole decellularization. This uses intrinsic vasculature perfuse decellularizing agent into tissue, effectively penetrating removing cellular material. The regenerated bioscaffolds could serve source of donation. study focused on...
OBJECTIVE: To assess the efficacy of desmopressin and imipramine in reducing urination frequency, retaining instilled suspension bladder without maintaining mouse under anesthesia. METHOD: Twenty-four mice were divided into four groups: (1) control, (2) four-hour water deprivation, (3) two µg/kg intraperitoneal desmopressin, (4) plus 30 mg/kg gavage. Micturition frequency was recorded using voiding spot assay. Animals catheterized 50 µl methylene blue bladder. The then placed on a white...
Abstract Background : This study was conducted to investigate the effects of intravitreal injection bone marrow mononuclear stem cells (BMMNC) on neurological and vascular damages in a rat model retinopathy prematurity (ROP). Methods Ten newborn Wistar rats were divided randomly into control oxygen-induced (OIR) group. Animals OIR group incubated an oxygen chamber induce retinopathy. One eye animals received BMMNC suspension (treated eyes), contralateral same volume saline injection. Then,...
<title>Abstract</title> Mature silkworms (Bombyx mori) and their pupae contain a variety of growth factors proteins such as bombyrin that can be used in many repair processes. Due to its appropriate qualities, the silkworm has been explored for use nerve regeneration. First Mori) Pupae Extracts were prepared. Then concentration type amino acids extracts evaluated by Bradford assay, SDS-page, LC-MS/MS. Also, regenerative potential improving Schwann cell proliferation axon was examined MTT,...