Ayae Saiki

ORCID: 0000-0002-1926-2022
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About
Contact & Profiles
Research Areas
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Medical Imaging and Pathology Studies
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Case Reports on Hematomas
  • Adenosine and Purinergic Signaling
  • Spinal Hematomas and Complications
  • Cancer-related gene regulation
  • Protein Degradation and Inhibitors
  • Viral Infections and Immunology Research
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Eosinophilic Disorders and Syndromes
  • Ubiquitin and proteasome pathways
  • Amino Acid Enzymes and Metabolism
  • Hematological disorders and diagnostics
  • Sulfur Compounds in Biology
  • Infectious Diseases and Tuberculosis
  • Monoclonal and Polyclonal Antibodies Research
  • Long-Term Effects of COVID-19
  • Sepsis Diagnosis and Treatment

Chiba University Hospital
2025

Japanese Red Cross Medical Center
2021-2022

Social Welfare Organization Saiseikai Imperial Gift Foundation
2021

Chibaken Saiseikai Narashino Hospital
2021

Juntendo University Hospital
2021

Kindai University
2021

Fukushima Medical University
2021

Lysinuric protein intolerance (LPI) is an autosomal recessive disease and pulmonary alveolar proteinosis a respiratory complication. A Japanese man in his 30s, diagnosed with LPI infancy, was interstitial lung (ILD) similar to fibrotic nonspecific pneumonia (f-NSIP) based on the findings of transbronchial cryobiopsy (TBLC). The function deteriorated, nintedanib administered. Two years after initiation therapy, patient hospitalized for acute exacerbation pneumonia. Corticosteroid pulse...

10.2169/internalmedicine.4074-24 article EN Internal Medicine 2025-01-01

Although sotrovimab, one of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) neutralizing antibodies has been shown to be effective in patients with mild-to-moderate disease 2019 (COVID-19) risk factors, their efficacy mRNA COVID-19 vaccinated omicron era is unknown. To evaluate effectiveness sotrovimab clinical data from both and unvaccinated who were hospitalized receiving at Japanese Red Cross Medical Center compared. The adverse events evaluated. Of total 60 enrolled this...

10.5582/ddt.2022.01036 article EN Drug Discoveries & Therapeutics 2022-06-24

Pulmonary amyloidosis is a rare disease characterized by abnormal extracellular deposition of amyloid fibril in the lung tissue, and identification deposits essential for its diagnosis. Surgical biopsy (SLB) standard diagnostic method pulmonary amyloidosis. However, it has relatively high post-procedural mortality rate. Recently, transbronchial cryobiopsy (TBLC) been gradually used diagnosing interstitial disease. efficacy not yet validated. Here, we describe two cases with light chain...

10.1016/j.rmcr.2022.101688 article EN cc-by Respiratory Medicine Case Reports 2022-01-01

Patients with idiopathic pulmonary fibrosis (IPF) occasionally experience acute exacerbations after surgery for lung cancer. Several recent studies have revealed a prophylactic effect of perioperative pirfenidone treatment on postoperative IPF in patients A 75-year-old woman consulted her pulmonologist because an shadow detected by follow-up chest computed tomography 2 months surgical biliary Another 7 later, showed 23- × 14-mm nodule located the right lower lobe high accumulation...

10.1177/03000605211016998 article EN cc-by-nc Journal of International Medical Research 2021-09-01

Background: Many patients with IPF typically visit a hospital chronic respiratory symptoms and then the diagnosis is made.However, some are incidentally diagnosed IPF.Aims: This study was planned to investigate clinical course prognostic factors in who were diagnosed.Methods: A hundred seven consecutive between January 2008 August 2017 retrospectively reviewed.Results: Of 107 patients, 35 (32.7%) (31 men 4 women).The mean age of them 73.9 AE 5.3 years.Mean FVC DLco 85.3 20.0% 80.1 21.9%...

10.1111/resp.14150_969 article EN Respirology 2021-11-01

We reported the performance of HFNC treatment on patients in our center from June 2020 to February 2021 Result: Ten have been treated with therapy after failure conventional oxygen (SpO 2 lower than 90% masked 10 liters/minutes).All them were diagnosed acute exacerbation interstitial lung disease, mostly lungs damaged and could not recover.We machines OmniBlender (CareFusion, USA).HFNC showed effectiveness clinical symptom improvement, decreasing respiratory rates (from 30 AE 3 breaths/min...

10.1111/resp.14150_823 article EN Respirology 2021-11-01
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