A5069309244- Cancer Risks and Factors
- Chronic Myeloid Leukemia Treatments
- Acute Myeloid Leukemia Research
- Acute Lymphoblastic Leukemia research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Pregnancy and preeclampsia studies
- Family Support in Illness
- COVID-19 Impact on Reproduction
- Ferrocene Chemistry and Applications
- Global Cancer Incidence and Screening
- Kruppel-like factors research
- Multiple and Secondary Primary Cancers
- Eosinophilic Disorders and Syndromes
- Diagnosis and treatment of tuberculosis
- Ectopic Pregnancy Diagnosis and Management
- Reproductive System and Pregnancy
- Tuberculosis Research and Epidemiology
- Childhood Cancer Survivors' Quality of Life
- Infant Nutrition and Health
- Complement system in diseases
- Breastfeeding Practices and Influences
- Healthcare Systems and Public Health
- Birth, Development, and Health
- Mycobacterium research and diagnosis
- Maternal and fetal healthcare
National Medical Research Center for Obstetrics, Gynecology and Perinatology named after Academician V.I.Kulakov of the Ministry of Healthcare of the Russian Federation
2015-2024
Central Scientific Research Institute of Tuberculosis Russian Academy of Medical Sciences
2023
Central Research Institute
2023
Ministry of Health of the Russian Federation
2021
Medizinische Hochschule Hannover
2019
The effects of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in women on the gestation course and health fetus, particularly first second trimesters, remain very poorly explored. This report describes a case which normal development pregnancy was complicated immediately after patient had experienced Coronavirus disease 2019 (COVID-19) at 21st week gestation. Specific conditions included critical blood flow fetal umbilical artery, growth restriction (1st percentile),...
The management of chronic myeloid leukemia (CML) diagnosed during pregnancy is a rare and challenging situation. We report the treatment outcome 87 cases in phase from 2001-2022 derived largest international observational registry, supported by European LeukemiaNet (ELN), 400 pregnancies 299 CML women. Normal childbirth occurred 76% without an increased rate birth abnormalities or life-threatening events, including patients untreated treated with interferon-α and/or imatinib 2nd-3rd...
Evaluation of clinical course COVID-19 during pregnancy and maternal perinatal outcomes this pregnancy.
Both favorable pregnancy outcomes and fetal abnormalities have been associated with the use of tyrosine kinase inhibitors (TKIs) during pregnancy. The placental transfer TKIs in humans is poorly understood. We observed women chronic myeloid leukemia who used imatinib or nilotinib late stages. newborns had no birth abnormalities. evaluated drug concentrations maternal blood, umbilical cord samples collected labor. found limited TKIs. fetal/maternal concentration ratio ranged from 0.5 to 0.58...
Summary This cohort study of the International Network on Cancer, Infertility and Pregnancy (INCIP) reports maternal neonatal outcomes 80 pregnant patients diagnosed with non‐Hodgkin lymphoma (NHL) between 1986 2019, focussing 57 (71%) diffuse large B‐cell (DLBCL). Of all patients, 54 (68%) received chemotherapy; mostly (89%) CHOP‐like (cyclophosphamide, doxorubicin, vincristine, prednisone) regimens. Four early pregnancies were terminated. Among 76 ongoing pregnancies, there was one...
The development of National clinical guidelines on diagnosis and treatment Ph-negative myeloproliferative neoplasms comes in response to the need standardize approach treatment. availability can facilitate choice adequate strategy, provides practicing physicians with exhaustive up-to-date information advantages shortcomings different methods as well lets health professionals better assess expected extents required by patients. In 2013 a working group was formed develop formulate neoplasms....
Breastfeeding in patients with chronic myeloid leukaemia (CML) during tyrosine kinase inhibitors (TKIs) therapy is not recommended but interruption of TKI treatment may cause the loss remission. We studied 3 cases pregnancy and breastfeeding women CML observed that stopping without major molecular response end haematological relapse. The concentrations nilotinib imatinib maternal milk were measured distribution human breast was demonstrated for first time. estimated maximal doses which an...
The breastfeeding of infants by mothers who are infected with SARS-CoV-2 has become a dramatic healthcare problem. WHO recommends that women should not abandon breastfeeding; however, there is still the risk contact transmission. Convalescent donor milk may provide defense against aforementioned issue and can eliminate consequences artificial feeding. Therefore, it vital to characterize epitope-specific immunological landscape human from recovered COVID-19. We carried out comprehensive...
Background: Patients with relapsed/refractory (R/R) AML have a dismal prognosis. Currently, no salvage chemotherapy regimen has gained universal acceptance. Selinexor, an oral inhibitor of the nuclear export protein exportin-1 (XPO-1), is blocking transport tumor suppressor and growth regulatory proteins from nucleus shown encouraging activity in AML. Based on these findings, we initiated study combining selinexor standard patients acute Aims: The primary objectives were to determine...
The development of National clinical guidelines on diagnosis and treatment Ph-negative myeloproliferative neoplasms provides the knowledge basis for decision making in diagnosis, therapy, prevention, rehabilitation compliance with evidence-based medicine principles order to ensure appropriate medical care a particular setting. underly choice optimal methods as part patient’s care, criteria assessment quality, standards, procedures, setting standards equipment management diagnostic...
Habitual miscarriage is a fairly common complication of early pregnancy. In the opinion most authors, term habitual used to describe loss two or more pregnancies during first 22 weeks Issues terminology and management continue be relevant debatable in medical professional communities need further discussion. addition sides issue, has significant psychological impact on women their partners. Regardless gestational age, pregnancy for couples similar importance newborn associated with hope...
Introduction . Pregnancy is one of the most frequent triggers congenital and acquired forms thrombotic thrombocytopenic purpura (TTP). Aim — to develop tactics for treatment pregnant women with TTP. Results TTP was associated pregnancy in 55.5 % all cases women. In 5 pregnancies which diagnosis known before pregnancy, or established early stages, treated throughout pregnancy. form, plasma transfusions were performed once every two weeks until 20th week weekly, if thrombocytopenia < 150 ×...
In the Russian Federation, there is an increase in patients with pulmonary tuberculosis combination comorbid pathologies, including Crohn's disease. There also a tendency to of and non-tuberculosis mycobacteriosis, which makes it difficult select adequate therapy reduces effectiveness treatment. Bronchial one complications process often masks onset this connection, diagnosis bronchi difficult. A young patient history disease was diagnosed bronchial mycobacteriosis. Upon admission, presence...
Aim. To evaluate the impact of changes in treatment pregnancy with breast cancer on condition and characteristics newborn. Design. Retrospective prospective cohort study. Materials methods. Evaluation comparison data management newborns two groups. The first group consisted 68 born to mothers from 2013 2019, medical records were collected analyzed retrospectively. second (prospective) included 75 children during 2020 2023. study was conducted basis department newborn National Medical...
.