A5015542767- Economic and Financial Impacts of Cancer
- Health Systems, Economic Evaluations, Quality of Life
- Palliative Care and End-of-Life Issues
- Clinical practice guidelines implementation
- Global Cancer Incidence and Screening
- Lung Cancer Treatments and Mutations
- Patient-Provider Communication in Healthcare
- Advances in Oncology and Radiotherapy
- Cancer Immunotherapy and Biomarkers
- Electronic Health Records Systems
- Medication Adherence and Compliance
- Pharmaceutical studies and practices
- Lung Cancer Research Studies
- Cancer Genomics and Diagnostics
- Telemedicine and Telehealth Implementation
- Discourse Analysis and Cultural Communication
- COVID-19 and healthcare impacts
- Frailty in Older Adults
- Health and Medical Research Impacts
- Bladder and Urothelial Cancer Treatments
- Biomedical Text Mining and Ontologies
- Safe Handling of Antineoplastic Drugs
- Patient Satisfaction in Healthcare
- Multiple Myeloma Research and Treatments
- Cancer survivorship and care
Cancer Institute (WIA)
2018-2024
Penn Center for AIDS Research
2023-2024
University of Pennsylvania Health System
2023-2024
University of Pennsylvania
2022-2024
eHealth Initiative
2024
Abramson Cancer Center
2024
University of Rochester Medical Center
2010-2023
Dana-Farber Cancer Institute
2019-2021
Harvard University
2019
The University of Adelaide
2019
<h3>Importance</h3> Financial toxicity (FT), unintended and unanticipated financial burden experienced by cancer patients undergoing care, is associated with negative consequences increased risk of mortality. Older (≥70 years) are at for FT, yet data limited on FT whether oncologists discuss their patients. <h3>Objective</h3> To examine the prevalence in older adults advanced cancer, its association health-related quality life (HRQoL), cost conversations between <h3>Design, Setting,...
BACKGROUND Chest wall progression of breast carcinoma after failure salvage surgery, radiation, and chemohormonal therapy is a quagmire with limited therapeutic options. Because photodynamic (PDT) offers excellent results in cutaneous lesions, PDT may play role this indication. However, to the authors' knowledge, published data for subgroup patients using only commercially available photosensitizing agent, Photofrin, often show high treatment morbidity, limiting PDT's usefulness. The authors...
Few antiviral therapies have been studied in patients with coronavirus disease 2019 (COVID-19) and kidney impairment. Herein, the efficacy, safety, pharmacokinetics of remdesivir, its metabolites, sulfobutylether-β-cyclodextrin excipient were evaluated hospitalized COVID-19 severe In REDPINE, a phase 3, randomized, double-blind, placebo-controlled study, participants aged ≥12 years for pneumonia acute injury, chronic disease, or failure randomized 2:1 to receive intravenous remdesivir (200...
ASCO Standards are evidence-based standards to provide frameworks for best practices in cancer care, following the development process as outlined Policies and Procedures Manual . follow Conflict of Interest Policy Clinical Practice Guidelines other guidance (“Guidance”) provided by is not a comprehensive or definitive guide treatment options. It intended voluntary use providers should be used conjunction with independent professional judgment. Guidance may applicable all patients,...
TPS1659 Background: Financial toxicity, the material and psychological burden of treatment cost, affects up to half people with cancer can affect adherence survival. toxicity is a health equity issue, disproportionately affecting Black patients. Patient education about cost patient-provider discussions are recommended mitigate financial but occur infrequently. Our goal through tailorable communication intervention, DISCO App. The App was shown be feasible, acceptable, preliminarily effective...
Five Buffalo, New York physicians provided carbon copies of their written pharmaceutical prescriptions to the investigators. The patients were contacted by telephone and asked completely read label prescribed medication describe itself. It was found that nearly 10 per cent sampled (N=223) dispensed with some form error. Recommendation is made request bring currently used medications them on physician office visits.
More oncologists desire to treat their patients with immune checkpoint inhibitors (ICIs) in the inpatient setting as use has become more widespread for numerous oncologic indications. This is cost-prohibitive and institutions because of high drug cost lack reimbursement setting. We sought examine current practice ICI administration determine if which clinical scenarios it may provide significant benefit therefore be warranted regardless cost.We conducted a retrospective chart review adult...
Introduction Carboplatin is widely used to treat lung cancer in the United States as an alternative cisplatin. Several studies have demonstrated that cisplatin-based regimen associated with a high frequency of thromboembolic complications. However, there has been limited investigation directly comparing risk events (TEEs) between cisplatin- and carboplatin-treated patients cancer. Methods All treated cisplatin or carboplatin at Wilmot Cancer Center, University Rochester 2011 2014 were...
Whole-brain radiation therapy (WBRT) remains standard practice for cerebral metastases, either as monotherapy or in conjunction with surgery stereotactic radiosurgery (SRS).1 Although potential radiation-induced side effects after WBRT are well described, we report the first (to our knowledge) case of fatal leukoencephalopathy following and SRS boost.
PURPOSE: Cancer clinical trial accrual rates are low, and information about contributing factors is needed. We examined video-recorded interactions to identify circumstances under which patients potentially eligible for a at major cancer center were offered trial. METHODS: conducted qualitative directed content analysis of 62 recorded with physicians (n = 13) intermediate- or high-risk prostate 43). Patients screened observed coded the in 3 steps: (1) classification all as explicit offer,...
Abstract Background Financial toxicity, the material and psychological burden of cost treatment, affects 30–50% people with cancer, even those health insurance. The treatment can affect adherence and, ultimately, mortality. toxicity is a equity issue, disproportionately affecting patients who are racial/ethnic minorities, have lower incomes, < 65 years old. Patient education about patient-oncologist discussions recommended as ways to address financial toxicity; however, research shows...
Drawing from insights communication science and behavioral economics, the University of Pennsylvania Telehealth Research Center Excellence (Penn TRACE) is designing testing telehealth strategies with potential to transform access care, care quality, outcomes, health equity, health-care efficiency across cancer continuum, an emphasis on understanding mechanisms action. Penn TRACE uses lung as exemplar model for screening treatment survivorship. We bring together a diverse interdisciplinary...
PURPOSE Less than half of the patients with newly diagnosed metastatic non–small cell lung cancer (NSCLC) undergo comprehensive molecular testing. We designed an electronic medical record (EMR)–based “nudge intervention” to prompt plasma-based testing at time initial oncology consultation. METHODS A nonrandomized prospective trial was conducted University Pennsylvania's academic practice and two affiliated community practices. Molecular genotyping performed by tissue- and/or next generation...
Ineffective handoffs contribute to gaps in patient care and medication errors, which jeopardize safety lead poor-quality care. The project aims are develop implement a standardized handoff process using an electronic medical record (EMR)-based tool ensure optimal communication of treatment-related information for patients receiving cancer treatment between oncology nurses.A multidisciplinary team convened standard safe process. intervention was developed over series phases Plan-Do-Study-Act...
The purpose of this paper is to provide an assessment the impact Enterprise-wide Risk Management (ERM) on trading activities financial institutions, with emphasis derivatives. This divided into three parts. first part looks at evolution ERM in terms its culture organization, risk coverage, measurement methodologies, technology and performance measurement. second application as it relates individual types such market, credit, business risks. concludes overview key factors that are critical...
e22037 Background: Financial toxicity, or the strain caused by paying for health care services, can undermine mental and QoL of patients (pts) in cancer care. This study examined associations FT with depression, anxiety, older pts advanced cancer. Methods: is a secondary analysis baseline data from Geriatric Assessment intervention conducted UR NCORP (URCC 13070; PI: Mohile). At baseline, were categorized as experiencing if they reported any one following: delaying medications due to cost,...
One of the most challenging clinical problems in oncology for patients, families, and clinicians is occurrence multiple symptoms. Unrelieved symptoms result decreased functional status quality life increased distress mortality (Cleeland et al., 2013; Flannery, Phillips, & Lyons, 2009; Reilly 2013). Although experience co-occurring well established as a frequently occurring issue, research establishing effective interventions has been minimal.