A5055384338- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Air Quality Monitoring and Forecasting
- Energy and Environment Impacts
- Vehicle emissions and performance
- Atmospheric chemistry and aerosols
- Noise Effects and Management
- Global Health Care Issues
- Heavy Metal Exposure and Toxicity
- Effects and risks of endocrine disrupting chemicals
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Birth, Development, and Health
- Quantum Dots Synthesis And Properties
- Mesoporous Materials and Catalysis
- Antiplatelet Therapy and Cardiovascular Diseases
- Venous Thromboembolism Diagnosis and Management
- Acute Myocardial Infarction Research
- Acute Ischemic Stroke Management
- Cardiac electrophysiology and arrhythmias
- Environmental Justice and Health Disparities
- Advanced Materials Characterization Techniques
- Smoking Behavior and Cessation
- Urban Transport and Accessibility
- Advanced X-ray and CT Imaging
- Health, Environment, Cognitive Aging
University of Rochester
2016-2025
University of Rochester Medical Center
2016-2025
University of Pennsylvania
2024-2025
Royal Ottawa Mental Health Centre
2024
Strong Memorial Hospital
2024
Royal Marsden Hospital
2024
University of Kentucky
2023
Ipsen (United Kingdom)
2021
Lafayette College
2020
Duke Institute for Health Innovation
2019
The American Thoracic Society has previously published statements on what constitutes an adverse effect health of air pollution in 1985 and 2000. We set out to update broaden these past that focused primarily effects the respiratory system. Since then, many studies have documented other organ systems, such as cardiovascular central nervous systems. In addition, new biomarkers been developed applied studies. This current report seeks integrate latest science into a general framework for...
Background: A growing body of evidence has associated maternal exposure to air pollution with adverse effects on fetal growth; however, the existing literature is inconsistent.Objectives: We aimed quantify association between particulate and term birth weight low (LBW) across 14 centers from 9 countries, explore influence site characteristics assessment methods between-center heterogeneity in this association.Methods: Using a common analytical protocol, International Collaboration Air...
<h3>Context</h3>Air pollution is a risk factor for cardiovascular diseases (CVD), but the underlying biological mechanisms are not well understood.<h3>Objective</h3>To determine whether markers related to CVD pathophysiological pathways (biomarkers systemic inflammation and thrombosis, heart rate, blood pressure) sensitive changes in air pollution.<h3>Design, Setting, Participants</h3>Using quasi-experimental opportunity offered by greatly restricted emissions during Beijing Olympics, we...
We and others have shown that increases in particulate air pollutant (PM) concentrations the previous hours days been associated with increased risks of myocardial infarction, but little is known about relationships between pollution specific subsets such as ST-elevation infarction (STEMI) non (NSTEMI). Using data from acute coronary syndrome patients STEMI (n = 338) NSTEMI 339) case-crossover methods, we estimated risk ambient fine particle (<2.5 um) concentrations, ultrafine (10-100 nm)...
Rationale: Unprecedented pollution control actions during the Beijing Olympics provided a quasi-experimental opportunity to examine biologic responses drastic changes in air levels.Objectives: To determine whether levels of biomarkers reflecting pulmonary inflammation and systemic oxidative stress were associated with healthy young adults.Methods: We measured fractional exhaled nitric oxide, number breath condensate markers (H+, nitrite, nitrate, 8-isoprostane), urinary...
The 2017–2019 hourly particle number size distributions (PNSD) from 26 sites in Europe and 1 the US were evaluated focusing on 16 urban background (UB) 6 traffic (TR) framework of Research Infrastructures services reinforcing air quality monitoring capacities European URBAN & industrial areaS (RI-URBANS) project. main objective was to describe phenomenology ultrafine particles (UFP) with a significant focus. varying lower detection limits made it difficult compare PN concentrations (PNC),...
Epidemiologic studies have demonstrated a consistent link between sudden cardiac deaths and particulate air pollution. We used implanted cardioverter defibrillator (ICD) records of ventricular tachyarrhythmias to assess the role pollution as trigger these potentially life-threatening events. The study cohort consisted 203 patients with ICD devices in Boston metropolitan area who were followed for an average 3.1 years 1995 2002. Fine particle mass gaseous plus temperature relative humidity...
The authors evaluated the association between ventricular arrhythmias detected by implantable cardioverter defibrillators and ambient air pollution concentrations in hours immediately before arrhythmia. Patients given at New England Medical Center Boston, Massachusetts, mid-1995 1999 who lived within 40 km of a central monitoring site (n = 203) were followed until July 2002. used case-crossover design to study up 798 confirmed among 84 subjects. found that interquartile range increases...
Previous studies have reported decreased birth weight associated with increased air pollutant concentrations during pregnancy. However, it is not clear when pregnancy increases in pollution are the largest differences weight.Using natural experiment of declines 2008 Beijing Olympics, we evaluated whether having specific months (i.e., 1st…8th) Olympics period was larger weights, compared pregnancies same dates 2007 or 2009.Using n = 83,672 term births to mothers residing four urban districts...
Rationale: Fine particulate matter air pollution of 2.5 μm or less in diameter (PM2.5) has been associated with an increased risk respiratory disease, but assessments specific infections adults are lacking.Objectives: To estimate the rate infection healthcare encounters acute increases PM2.5 concentrations.Methods: Using case–crossover methods, we studied 498,118 adult New York State residents a primary diagnosis influenza, bacterial pneumonia, culture-negative pneumonia upon hospitalization...
Using a quasi-experimental opportunity offered by greatly restricted air pollution emissions during the Beijing Olympics compared to before and after Olympics, we conducted current study compare ultrafine particles (UFPs) fine (PM2.5) in their associations with biomarkers reflecting multiple pathophysiological pathways linking exposure cardiorespiratory events. Number concentrations of (13.0-764.7 nm) mass PM2.5 were measured at two locations within 9 km from residence workplace 125...
Mechanisms underlying previously reported air pollution and cardiovascular (CV) morbidity associations remain poorly understood.We examined between markers of pathways thought to underlie these CV ambient particle concentrations in postinfarction patients.We studied 76 patients, from June 2006 November 2009, who participated a 10-week cardiac rehabilitation program following recent (within 3 months) myocardial infarction or unstable angina. Ambient ultrafine (UFP; 10-100 nm), accumulation...
The response of respiratory infections to source-specific particulate matter (PM) is an area active research. Using PM2.5 concentrations at six urban sites in New York State, a case-crossover design, and conditional logistic regression, we examined the association between PM rate hospitalizations emergency department (ED) visits for influenza or culture-negative pneumonia from 2005 2016. There were most N = 14 764 hospitalizations, 57 522 ED visits, 274 226 113 997 included our analyses. We...
Previous studies reported triggering of acute cardiovascular events by short-term increasedPM2.5 concentrations. From 2007 to 2013, national and New York state air quality policies economic influences resulted in reduced concentrations PM2.5 other pollutants across the state. We estimated rate hospital admissions associated with increased previous 1-7 days, evaluated whether they differed before (2005-2007), during (2008-2013), after these concentration changes (2014-2016).Using Statewide...
There is concern regarding the heterogeneity of exposure to airborne particulate matter (PM) across urban areas leading negatively biased health effects models. New, low-cost sensors now permit continuous and simultaneous measurements be made in multiple locations. Measurements ambient PM were from October April 2015–2016 2016–2017 assess spatial temporal variability relative importance traffic wood smoke outdoor concentrations Rochester, NY, USA. In general, there was moderate...
Previous work reported increased rates of acute cardiovascular hospitalizations associated with PM2.5 concentrations in the previous few days across urban centers New York State from 2005 to 2016. These relative were higher after air quality policies and economic changes resulted decreased PM composition (e.g. secondary organic carbon), compared before during these changes. Changes sources may explain this difference.To estimate rate increases source specific concentrations.Using apportioned...
Prior studies reported that exposure to increased concentrations of fine particulate matter (PM2.5) were associated with rates hospitalization and emergency department (ED) visits for asthma chronic obstructive pulmonary disease (COPD). In this study, examined from 2005 2016 using a case-crossover design ascertain if there have been changes in the per unit mass given substantial reductions PM2.5 concentration its composition. reduced through combination policies designed improve air quality...
Phthalate exposure is widespread among pregnant women and may be a risk factor for preterm birth. To investigate the prospective association between urinary biomarkers of phthalates in pregnancy birth individuals living US. Individual-level data were pooled from 16 preconception studies conducted Pregnant who delivered 1983 2018 provided 1 or more urine samples during included. Urinary phthalate metabolites quantified as exposure. Concentrations 11 standardized dilution mean repeated...
Since the Clean Air Act amendments of 1970, various efforts have been made in United States to control ambient particulate matter and improve air quality. Although substantial progress had by end 1990s, further reductions were needed meet National Ambient Quality Standards. To assess effectiveness regulations impacts economic drivers, we investigated PM2.5 source trends at 11 sites New York Jersey for 2010–2019 period. Dispersion-normalized positive matrix factorization (DN-PMF) was used...
During the past two decades, efforts have been made to further reduce particulate air pollution across New York State through various Federal and policy implementations. Air quality has also affected by economic drivers like 2007–2009 recession changing costs for different approaches electricity generation. Prior work focused on matter with aerodynamic diameter ≤2.5 μm. However, there is interest in effects of ultrafine particles health environment analyses changes particle number...
We reported previously that 24-hr moving average ambient air pollution concentrations were positively associated with ventricular arrhythmias detected by implantable cardioverter defibrillators (ICDs). ICDs also detect paroxysmal atrial fibrillation episodes (PAF) result in rapid rates. In this same cohort of ICD patients, we assessed the association between and PAF.We performed a case-crossover study.Patients who lived Boston, Massachusetts, metropolitan area had implanted June 1995...
<h3>Background:</h3> Previous studies of air pollution and birth outcomes have not evaluated whether complicated pregnancies might be susceptible to the adverse effects pollution. It was hypothesised that trimester mean pollutant concentrations could associated with fetal growth restriction, larger risks among pregnancies. <h3>Methods:</h3> A multiyear linked certificate maternal/newborn hospital discharge dataset singleton, term births mothers residing in New Jersey at time birth, who were...
The purpose of the present study was to examine risk stillbirth associated with ambient air pollution during pregnancy. Using live birth and fetal death data from New Jersey 1998 2004, authors assigned daily concentrations each or death. Generalized estimating equation models were used estimate relative odds interquartile range increases in mean pollutant first, second, third trimesters throughout entire significantly increased 10-ppb increase nitrogen dioxide concentration first trimester...