A5022980983- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Peripheral Neuropathies and Disorders
- Liver Disease Diagnosis and Treatment
- Multiple Sclerosis Research Studies
- Nail Diseases and Treatments
- Heparin-Induced Thrombocytopenia and Thrombosis
- Fungal Infections and Studies
- Infectious Diseases and Mycology
- Sepsis Diagnosis and Treatment
- Lichen and fungal ecology
- Plant Pathogens and Fungal Diseases
- Immune responses and vaccinations
- Virus-based gene therapy research
- Herpesvirus Infections and Treatments
- vaccines and immunoinformatics approaches
- Antifungal resistance and susceptibility
- Kawasaki Disease and Coronary Complications
Hospital Universitario de La Princesa
2020-2025
Hospital Clínico Universitario Virgen de la Victoria
2011
ABSTRACT We previously conducted a multicenter surveillance study on Candida epidemiology and antifungal resistance in Madrid (CANDIMAD study; 2019–2021), detecting an increase fluconazole-resistant parapsilosis . here present data isolates collected 2022. Furthermore, we report the trends during entire period, including analysis per ward of admission. spp. incident from blood cultures intra-abdominal samples patients cared for at 16 hospitals Madrid, Spain, were tested with EUCAST E.Def...
Antibody detection is essential to establish exposure, infection, and immunity SARS-CoV-2, as well perform epidemiological studies. The worldwide urge for new diagnostic tools control the pandemic has led a quick incorporation in clinical practice of recently developed serological assays. However, only few comparative studies have been published, there lack data about accuracy currently available We evaluated detect Ig G, M+A, and/or IgA anti SARS-CoV-2 10 different assays: lateral flow card...
The identification of filamentous fungi by matrix-assisted laser desorption/ionization–time flight mass spectrometry (MALDI–TOF MS) represents a challenge due to their complex taxonomy and the lack comprehensive databases. aim this study was evaluate current status available MALDI–TOF MS databases for dermatophytes, including commercial, in-house, web-based We collected 289 dermatophyte strains from different centers analyzed them using four combination them. commercial in-house shown...
Immune dysregulation in individuals with Down syndrome (DS) leads to an increased risk for hospitalization and death due coronavirus disease 2019 (COVID-19) may impair the generation of protective immunity after vaccine administration.
Background: To describe the effectiveness and safety of COVID-19 vaccine in a series patients with rheumatoid arthritis (RA). Methods: Retrospective single-center study RA patients, fulfilling ACR 1987 or ACR/EULAR 2010 classification criteria, that received first between December 2020 October 2021, had post-vaccination serology subsequent follow-up at least 6 months university hospital. Vaccine was evaluated by serological response incidence post-vaccine COVID-19, adverse events (AE)...
We analyzed immune response to SARS-CoV-2 vaccination by measuring specific IgG titers and T-cell reactivity different peptides in multiple sclerosis patients taking disease-modifying treatments. Of the 88 included, 72 developed any kind of after vaccination. Although DMTs such as fingolimod anti-CD20+ treatments prevented from developing a robust humoral vaccine, most them were still able develop cellular response, which could be crucial for long-term immunity. It is probably advisable that...
Presence of SARS-CoV-2 RNA in serum (viraemia) COVID-19 patients has been related to poor prognosis and death. The aim this study was evaluate the ability two commercial reverse real-time-PCR (rRT-PCR) kits, cobas (Cobas test) TaqPath CE-IVD RT-PCR Kit (Taqpath test), detect viraemia their implementation as routine diagnosis microbiology laboratory. This retrospective cohort conducted with 203 adult admitted Hospital Universitario de La Princesa, (89 Intensive Care Unit 114 ward) at least...
ABSTRACT Immune dysregulation in individuals with Down syndrome (DS) leads to an increased risk for hospitalization and death due COVID-19 may impair the generation of protective immunity after vaccine administration. The cellular humoral responses 55 DS patients who received a complete SARS-CoV-2 vaccination regime at one three (V1) six (V2) months were characterised. SARS-CoV-2-reactive CD4+ CD8+ T lymphocytes predominant Th1 phenotype observed V1, V2. Likewise, sustained increase...
We analyzed immune response to SARS-CoV-2 vaccination by measuring specific IgG titers and T-cell reactivity different peptides in multiple sclerosis patients taking disease-modifying treatments. Of the 88 included, 72 developed any kind of after vaccination. Although DMTs such as fingolimod anti-CD20+ treatments prevented from developing a robust humoral vaccine, most them were still able develop cellular response, which could be crucial for long-term immunity. It is probably advisable that...