- Luminescence Properties of Advanced Materials
- Luminescence and Fluorescent Materials
- Radiation Detection and Scintillator Technologies
- Perovskite Materials and Applications
- 3D Printing in Biomedical Research
- Nanoplatforms for cancer theranostics
- Innovative Microfluidic and Catalytic Techniques Innovation
- Microfluidic and Capillary Electrophoresis Applications
- Atomic and Subatomic Physics Research
- Microfluidic and Bio-sensing Technologies
- Lanthanide and Transition Metal Complexes
- Medical Imaging Techniques and Applications
- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- X-ray Diffraction in Crystallography
- Mass Spectrometry Techniques and Applications
- Solid-state spectroscopy and crystallography
- Nanocluster Synthesis and Applications
- Advanced Nanomaterials in Catalysis
- Photorefractive and Nonlinear Optics
- Optical Polarization and Ellipsometry
- Photonic and Optical Devices
- Crystallization and Solubility Studies
- Photoacoustic and Ultrasonic Imaging
- Photodynamic Therapy Research Studies
Fuzhou University
2020-2025
Tan Kah Kee Innovation Laboratory
2020-2024
University of Chinese Academy of Sciences
2023
National University of Singapore
2017-2021
Tsinghua University
2011-2019
Harvard University
2016-2019
Harvard University Press
2019
Electron Energy Corporation (United States)
2018
Shenzhen University
2017
Boston Applied Technologies (United States)
2004-2008
Scintillators, which are capable of converting ionizing radiation into visible photons, an integral part medical, security, and commercial diagnostic technologies such as X-ray imaging, nuclear cameras, computed tomography. Conventional scintillator fabrication typically involves high-temperature sintering, generating agglomerated powders or large bulk crystals, pose major challenges for device integration processability. On the other hand, colloidal quantum dot scintillators cannot be cast...
A new class of lanthanide-doped upconversion nanoparticles are presented that without Yb3+ or Nd3+ sensitizers in the host lattice. In erbium-enriched core-shell NaErF4 :Tm (0.5 mol %)@NaYF4 nanoparticles, a high degree energy migration between Er3+ ions occurs to suppress effect concentration quenching upon surface coating. Unlike conventional -Er3+ system, ion can serve as both sensitizer and activator enable an effective process. Importantly, appropriate doping Tm3+ has been demonstrated...
This paper reports a droplet-based microfluidic approach to fabricate large number of monodisperse, portable microtissues, each in an individual drop. We use water-water-oil double emulsions as templates and spatially assemble hepatocytes the core fibroblasts shell, forming 3D liver model
Scintillators that exhibit X-ray-excited luminescence have great potential in radiation detection, X-ray imaging, radiotherapy, and non-destructive testing. However, most reported scintillators are limited to inorganic or organic crystal materials, which some obstacles repeatability processability. Here we present a facile strategy achieve the phosphorescent scintillation from amorphous copolymers through copolymerization of bromine-substituted chromophores acrylic acid. These polymeric...
Luminescence clusters composed of organic ligands and metals have gained significant interests as scintillators owing to their great potential in high X-ray absorption, customizable radioluminescence, solution processability at low temperatures. However, luminescence efficiency is primarily governed by the competition between radiative states from nonradiative cluster-centered charge transfer. Here we report that a class Cu4I4 cubes exhibit highly emissive radioluminescence response...
Abstract Lead halide perovskites have made great advance in direct X‐ray detection, however the presence of toxic lead and requirement high working voltages severely limit their applicability operational stability. Thus, exploring “green” lead‐free hybrid capable detecting X‐rays at zero bias is crucial but remains toughly challenging. Here, utilizing chiral R / S ‐1‐phenylpropylamine ( ‐PPA) cations, a pair 0D chiral‐polar perovskites, 2 BiI 5 1 ) are constructed. Their intrinsic...
Abstract Achieving efficient photon upconversion under low irradiance is not only a fundamental challenge but also central to numerous advanced applications spanning from photovoltaics biophotonics. However, date, almost all approaches for luminescence intensification require stringent controls over factors such as composition and size of nanophosphors. Here, we report the utilization dielectric microbeads significantly enhance processes in lanthanide-doped nanocrystals. By modulating...
In this work, a stable isotope labeling assisted microfluidic chip electrospray ionization mass spectrometry (SIL-chip-ESI-MS) platform for qualitative and quantitative analysis of cell metabolism was developed. Microfluidic culture, drug-induced apoptosis analysis, measurements were performed simultaneously on the specifically designed device. MCF-7 cells cultivated in vitro exposed anticancer agent (genistein genistein-d(2)) cell-based drug assay. A dual-isotopic presented effective...
Abstract Singlet oxygen ( 1 O 2 ) has a potent anticancer effect, but photosensitized generation of is inhibited by tumor hypoxia and limited light penetration depth. Despite the potential chemodynamic therapy (CDT) to circumvent these issues exploration ‐producing catalysts, engineering efficient CDT agents still formidable challenge since most catalysts require specific pH function become inactivated upon chelation glutathione (GSH). Herein, we present catalytic microenvironment‐tailored...
Abstract Solution‐processed metal‐halide perovskites hold great promise in developing next‐generation low‐cost, high‐performance photodetectors. However, the weak absorption of beyond near‐infrared spectral region posts a stringent limitation on their use for broadband Here, rational design and synthesis an upconversion nanoparticles (UCNPs)–perovskite nanotransducer are presented, namely UCNPs@mSiO 2 @MAPbX 3 (X = Cl, Br, or I), photon detection spanning from X‐rays, UV, to NIR. It is...
Ultrasmall gold nanoclusters (AuNCs) are emerging as promising luminescent nanoprobes for bioimaging due to their fantastic photoluminescence (PL) and renal-clearable ability. However, it remains a great challenge design them in vivo sensitive molecular imaging desired tissues. Herein, we have developed strategy tailor the PL biofate of near-infrared II (NIR-II)-emitting AuNCs via ligand anchoring improved bioimaging. By optimizing types using Er3+-doped lanthanide (Ln) nanoparticles models,...
X-ray scintillators are widely used in medical imaging, industrial flaw detection, security inspection, and space exploration. However, traditional commercial usually associated with a high use cost because of their substantial toxicity easy deliquescence. In this work, an atomically precise Au-Cu cluster scintillator (1) thermally activated delayed fluorescence (TADF) property was facilely synthesized, which is environmentally friendly highly stable to water oxygen. The TADF 1 endows it...
X-ray imaging plays an increasingly crucial role in clinical radiography, industrial inspection, and military applications. However, current technologies have difficulty protecting against information leakage caused by brute force attacks via trial-and-error. Here high-confidentiality encryption fabricating ultralong radioluminescence memory films composed of lanthanide-activated nanoscintillators (NaLuF4 : Gd3+ or Ce3+ ) with imperceptible purely-ultraviolet (UV) emission is reported....
Abstract With the increasing demands of X‐ray detection and medical diagnosis, organic scintillators with intense tunable excited emission have been becoming important. To guarantee absorption, heavy atoms were widely added in reported scintillators, which led to quenching. In this work, we propose a new strategy realize through host‐guest doping strategy. Then absorption centers (host) (guest) are separated. Under excitation, these materials displayed readily emissions ranging from green...
Abstract Broadband emissive perovskites are next‐generation materials for solid‐state lighting and radiative detection. However, white‐emitting generally synthesized by regulating B/X sites, while not enough attention is paid to the A‐site, which thought hardly affect band‐edge structures optoelectronic properties. Here, a series of Sb 3+ ‐doped In‐based 0D halide perovskite derivatives described with various organoammonium cations in A‐sites. Warm‐white light emitting across visible...