- Inflammatory Bowel Disease
- Microscopic Colitis
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Gallbladder and Bile Duct Disorders
- Pancreatic and Hepatic Oncology Research
- Biliary and Gastrointestinal Fistulas
- Gastric Cancer Management and Outcomes
- Autoimmune and Inflammatory Disorders
- Gastrointestinal Tumor Research and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Diverticular Disease and Complications
- Pancreatitis Pathology and Treatment
- Gastrointestinal Bleeding Diagnosis and Treatment
- Celiac Disease Research and Management
- Metastasis and carcinoma case studies
- Liver Disease Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Colorectal Cancer Screening and Detection
- Medical research and treatments
- Helicobacter pylori-related gastroenterology studies
- Liver Disease and Transplantation
- Intestinal Malrotation and Obstruction Disorders
- Genetic factors in colorectal cancer
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2015-2024
Mútua Terrassa
2015-2024
Universitat de Barcelona
2012-2022
Centro de Investigación Biomédica en Red
2016-2022
Instituto de Salud Carlos III
2021
University Hospital Mútua de Terrassa
2015-2020
Abstract Background It is unclear whether the insertion of an axis-orienting double-pigtail plastic stent (DPS) through biliary lumen-apposing meal (LAMS) in EUS-guided choledochoduodenostomy (CDS) improves patency. The aim this study to determine technical variant offers a clinical benefit drainage (BD) for management distal malignant obstruction. Methods/design This multicenter open-label, randomized controlled trial with two parallel groups. Eighty-four patients obstruction will undergo...
Esophagogastroduodenoscopy (EGD) is an effective technique for diagnosing gastric cancer (GC). However, it estimated that 10% of GCs are unnoticed, constituting missed (MGC). To analyse the incidence MGC in our area, characteristics GC and factors related to were evaluated. This was a retrospective study patients diagnosed with at single centre between October 2003 December 2018. defined as undetected EGD performed 3 36 months before diagnosis. A total 333 identified, 6% whom had MGC. more...
It has been suggested that high titres of tTG are associated with elevated positive predictive values (PPV) for celiac disease. However, the PPV a strongly will depend on disease prevalence in different risk groups diseaseTo assess In addition, to calculate post-test probability setting routine clinical practice.145 consecutive patients tTG, and small bowel biopsy were included. The cut-off points levels diagnosis was assessed. cut-offs higher used likelihood ratio. A simulation practice...
There is very limited information regarding region-specific immunological response in human intestine. We aimed to determine differences immune compartmentalisation between ileum and colon healthy inflamed mucosa.T cell profile its apoptosis were measured by flow cytometry, Th1, Th17, Treg [CD4(+)CD25(+)FOXP3(+)], double positive [DP, CD3(+)CD4(+)CD8(+)] negative T cells [DN, CD3(+)CD4(-)CD8(-)], immunohistochemistry [FOXP3, caspase-3], real-time polymerase chain reaction [PCR] [IFN-γ,...
Abstract Background SARS-CoV-2 may produce intestinal symptoms that are generally mild, with a small percentage of patients developing more severe symptoms. The involvement in the physiopathology bowel damage is poorly known. Transmission electron microscopy (TEM) useful tool provides an understanding invasiveness, replication and dissemination body cells but information outside respiratory tract very limited. We report two cases complications (intestinal lymphoma ischaemic colitis) which...
Abstract Background Stenosis is one of the most common complications in patients with Crohn’s disease (CD). Endoscopic balloon dilation (EBD) treatment choice for a short stenosis adjacent to anastomosis from previous surgery. Self-expandable metal stents (SEMS) may be suitable option longer stenoses. To date, however, there no scientific evidence as whether endoscopic (EBD/SEMS) or surgical best approach de novo primary stenoses that are less than 10 cm length. Methods/design Exploratory...
Introduction: The study of intraepithelial lymphocytes (IEL) by flow cytometry is a useful tool in the diagnosis coeliac disease (CD). Previous data showed that an increase %TCRγδ+ and decrease %CD3− IEL constitute typical CD cytometric pattern with specificity 100%. However, there are no regarding whether differences related to sex, age, titers serology, degree histological lesion. Study aims: To confirm high diagnostic accuracy patterns. determine if between serology titers, lesion grade....
Previous studies suggested that Interleukin-10 (IL-10) depletion in Crohn's disease (CD) could predict outcome. To determine IL-10 blood and at different intestinal locations patients with active CD to assess its potential prognostic capacity identify aggressive CD. Twenty-three were included. Ulcerative colitis (UC), infectious healthy individuals acted as controls. Serum mucosal samples taken baseline 1 month after steroid initiation patients. Patients classified according response....
To evaluate the rate of adverse events (AEs) during consecutive gastric and duodenal polypectomies in several Spanish centers.Polypectomies protruded or polyps ≥ 5 mm using hot snare were prospectively included. Prophylactic measures hemorrhage allowed predefined cases. AEs defined graded according to lexicon recommended by American Society for Gastrointestinal Endoscopy. Patients followed 48 h, one week 1 mo after procedure.308 patients included a single polypectomy was performed 205. Only...
Aims It is unclear whether the insertion of an axis-orienting double-pigtail plastic stent (DPS) through biliary lumen-apposing metal stents (LAMS) in EUS-guided choledochoduodenostomy (CDS) improves patency. The aim to determine this technical variant offers a clinical benefit drainage (CDS-type) for management distal malignant obstruction.
Aims Percutaneous liver biopsy (PLB) has been considered as the main technique for diseases anatomopathological diagnosis. Endoscopic ultrasound-guided (EUS-LB) reported an alternative diagnostic method. The aim of our study is to compare yield and safety EUS-LB vs. PLB.
Despite pharmacological advances, strictures in Crohn's disease (CD) continues to be an important problem that leads a high percentage of patients undergo endoscopic and/or surgical treatments. There are currently no clinical scores or diagnostic tools allow predicting which will develop this complication, and when stricture is diagnosed, it usually already well established clinically relevant. The current role treatment limited treat inflammation once there significant fibrosis, the only...
It has been suggested that the diagnostic study of watery chronic diarrhoea functional characteristics should include a limited number tests, but which and in what order is not well established. Aim: To evaluate frequency microscopic colitis (MC) other diagnosis patients with without organic context clinical practice to establish best strategy. All submitted for colonoscopy due 2015–2016 period were included. Watery was defined as presence non-bloody ≥2 stools/day or at least 3 weekly...
An 80-year-old woman with pluripathology was admitted cholangitis. A computed tomography scan showed a dilated common bile duct (CBD) and possible distal choledocholithiasis. endoscopic retrograde cholangiopancreatography performed the swept balloon, revealing polypoid lesion of adenomatous appearance through papilla. The pathology confirmed tubulo-villous adenoma high grade focal dysplasia. ultrasound revealed presence 10 × 8 mm polyp in CBD ([Fig. 1]). As patient risk surgical candidate,...