A5029559819- Cancer, Lipids, and Metabolism
- Cancer Risks and Factors
- Inflammatory Biomarkers in Disease Prognosis
- Adipokines, Inflammation, and Metabolic Diseases
- Cervical Cancer and HPV Research
- Ferroptosis and cancer prognosis
- Nutrition and Health in Aging
- Gastric Cancer Management and Outcomes
- Diabetes Treatment and Management
- Pneumonia and Respiratory Infections
- Hepatitis B Virus Studies
- Cancer-related molecular mechanisms research
- Liver Disease Diagnosis and Treatment
- Metabolism, Diabetes, and Cancer
- Plant-based Medicinal Research
- Circular RNAs in diseases
- Antibiotics Pharmacokinetics and Efficacy
- Rice Cultivation and Yield Improvement
- Genetic Mapping and Diversity in Plants and Animals
- Synthesis and Catalytic Reactions
- Lung Cancer Diagnosis and Treatment
- Diabetes Management and Research
- Molecular Biology Techniques and Applications
- Pancreatic function and diabetes
- GABA and Rice Research
Henan Cancer Hospital
2013-2025
Zhengzhou University
2013-2025
China Medical University
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2013-2023
Shenyang 242 Hospital
2023
Qingdao University
2001-2022
Affiliated Hospital of Qingdao University
2021-2022
Nanjing Medical University
2022
University of Arizona
2005-2021
University of Arizona Cancer Center
2021
Therapeutic trials with high-dose lansoprazole and omeprazole have been shown to be sensitive clinical tools for diagnosing patients gastro-oesophageal reflux disease-related non-cardiac chest pain.To determine the value of a therapeutic trial rabeprazole over 7 days in detecting pain.Double-blind, randomized, placebo-controlled, crossover study. Patients referred by cardiologist after comprehensive cardiac work-up were enrolled into Oesophageal mucosal disease was determined upper endoscopy...
Although the correlation of HPV genotype with cervical precursor lesions and invasive cancer has been confirmed, role in prognosis is less conclusive. This study aims to systematically investigate independent prognostic cancer.A total 306 eligible patients provided cell specimens for genotyping before therapy had a median follow-up time 54 months after diagnosis. Survival times were measured from date diagnosis cancer-related death (overall survival, OS) recurrence or metastasis (disease...
To investigate the independent and joint associations of blood lipids lipoproteins with lung cancer risk in Chinese males, a prospective cohort study was conducted. A total 109,798 males baseline information on cholesterol (TC), triglycerides (TG), low‐density lipoprotein (LDL‐C), high‐density (HDL‐C) non‐HDL were prospectively observed from 2006 to 2015 for incidence. Cox proportional hazards models restricted cubic spline (RCS) analysis used estimate hazard ratios (HRs) 95% confidence...
Background Respiratory tract infections (RTIs) are a heavy burden on society. However, due to the complex etiology of RTIs, clinical diagnosis, treatment, and prevention these remain challenging, especially in developing countries. Methods To determine epidemiological characteristics 18 respiratory pathogens, we analyzed 12,502 patients with acute (ARIs) by performing polymerase chain reaction (PCR) patient pharyngeal swabs. Results Samples positive for at least 1 pathogen were obtained from...
To investigate the association between fasting blood glucose (FBG) levels and risk of incident primary liver cancer (PLC) in Chinese males, a large prospective cohort was performed current study. A total 109 169 males participating routine checkups every two years were recruited Kailuan male study since May 2006. Cox proportional hazards regression models restricted cubic spline (RCS) used to evaluate baseline FBG PLC. Compared with normal (3.9⩽FBG<6.1 mmol l−1), impaired (IFG: 6.1⩽FBG<7.0...
To investigate the association between risk of lung cancer and short-term body mass index (BMI) changes in male never-smokers a large population-based prospective study.
The ability of lung cancer screening to manage pulmonary nodules was limited because the high false-positive rate in current mainstream method, low-dose computed tomography (LDCT). We aimed reduce overdiagnosis Chinese population.Lung risk prediction models were constructed using data from a population-based cohort China. Independent clinical two programs performed Beijing and Shandong, respectively, used as external validation set. Multivariable logistic regression estimate probability...
As an important cytokine that modulate the cell cycle, involvement of transforming growth factor beta-1 (TGF-beta1) in carcinogenesis has been extensively studied for many years. Literatures have demonstrated TGF-beta1 gene polymorphisms may alter risk various cancers, such as lung, prostate and breast. To investigate whether can modify gastric cancer, we conduct this hospital-based, case-control study.One hundred sixty-seven cases 193 gender, age-matched healthy controls were enrolled...
Human cytochrome P450 4A11 (CYP4A11) plays a role in the regulation of blood pressure through conversion arachidonic acid into 20-hydroxyeicosatetraenoic (20-HETE). We therefore investigated association between CYP4A11 polymorphism (rs9333025) with hypertension Mongolian and Han ethnic groups. studied 514 Mongolians pastoral area, including 201 patients 313 normotensive controls, 524 individuals an urban 215 309 controls. Genotyping was performed using polymerase chain reaction (PCR)...
To examine the associations between fasting blood glucose (FBG) trajectories, changes in FBG over time and risk of cancer, particularly for gastrointestinal we enrolled 69,742 participants without diabetes from Kailuan cohort. trajectories (2006-2010) were modeled by group-based trajectory modeling, five identified: low-increasing (n = 6,275), moderate-stable 44,120), moderate-increasing 10,149), elevated-decreasing 5,244) elevated-stable 3,954). A total 1,364 cancer cases accumulated 2010...
Activation of the peroxisome proliferator-activated receptor g (PPARg) improves insulin sensitivity and inhibits atherosclerosis.Whether PPARg2 Pro12Ala polymorphism affects myocardial infarction is not clearly understood.We investigated a possible association with obesity in Han Chinese Hohhot, Inner Mongolia, China.We included 121 subjects 137 healthy controls our study.Triglycerides, total cholesterol, lowdensity lipoprotein high-density cholesterol were measured.The following information...
// Ni Li 1, * , Dong Hang 2, Lin Yang 3 Xiaoshuang Feng 1 Zhangyan Lyu Shuanghua Xie Jing Zhou 2 Lingying Wu 4 Xiaoguang Nan Min Cheng Kai Zhang 5 Zhihui 6 Hong Cui Jian Yin Zhibin Hu Hongbing Shen and Dai Program Office for Cancer Screening in Urban China, National Center/Cancer Hospital, Chinese Academy of Medical Sciences Peking Union College, Beijing, China Department Epidemiology Biostatistics, Collaborative Innovation Center Medicine, School Public Health, Nanjing University, Nanjing,...
Background. The present study is aimed at evaluating the functional and clinical values of P3H4 in lung adenocarcinoma. Moreover, we also investigated downstream pathways that might participate in. Methods. differential expression analysis was used to identify genes differentially expressed adenocarcinoma tissues as compared with normal tissues. Survival test association between survival time. Gene set enrichment conducted explore pathways. CCK8 transwell were employed examine impact on cell...
Background and Aim: Palmitic acid (PA, C16:0), one of the major saturated fatty acids in human milk fat being 17-25% acids, is esterified mainly at SN2-position (SN2-palmitate).Contrary vegetable oils, which are commonly used as source infant formulas, PA outer positions, i.e, SN1 SN3 resulting reduced absorption harder stools.SN2-palmitate prebiotics have been shown to improve digestion reduce stool hardness.Our aim was study potential effects SN2-palmitate addition formula-fed Chinese...
Objective: To assess the association and intensity of baseline TC level with incidence lung cancer in men China. Methods: Since May 2006, all male workers, including employees retirees Kailuan Group were recruited dynamic cohort study. Information about demographics, medical history, anthropometry collected at interview, as well information newly-diagnosed cases during follow-up period. According to guidelines for blood lipids Chinese adults distribution population, was classified into five...