Pengcheng Zhu

ORCID: 0000-0002-3618-8266
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About
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Research Areas
  • Cardiac, Anesthesia and Surgical Outcomes
  • Obsessive-Compulsive Spectrum Disorders
  • Colorectal Cancer Surgical Treatments
  • Enhanced Recovery After Surgery
  • Anorectal Disease Treatments and Outcomes
  • Intestinal and Peritoneal Adhesions
  • Autism Spectrum Disorder Research
  • Heat shock proteins research
  • Multimedia Communication and Technology
  • Cardiovascular Health and Risk Factors
  • Traditional Chinese Medicine Studies
  • High Altitude and Hypoxia
  • Spaceflight effects on biology
  • Eating Disorders and Behaviors
  • Health disparities and outcomes
  • Endoplasmic Reticulum Stress and Disease
  • Ferroptosis and cancer prognosis
  • Health Promotion and Cardiovascular Prevention
  • Hormonal Regulation and Hypertension
  • Renin-Angiotensin System Studies
  • Metabolomics and Mass Spectrometry Studies
  • Colorectal and Anal Carcinomas
  • RNA modifications and cancer
  • Genetic Associations and Epidemiology
  • Body Image and Dysmorphia Studies

Soochow University
2017-2024

Changshu No.1 People's Hospital
2018-2024

Xinjiang Medical University
2009-2023

Shanghai Jiao Tong University
2008-2020

XinHua Hospital
2013-2020

Second Affiliated Hospital of Soochow University
2017

Creative Commons
2017

First Affiliated Hospital of Xinjiang Medical University
2009-2013

Disulfidptosis, a regulated form of cell death, has been recently reported in cancers characterized by high SLC7A11 expression, including invasive breast carcinoma, lung adenocarcinoma, and hepatocellular carcinoma. However, its role colon adenocarcinoma (COAD) infrequently discussed. In this study, we developed validated prognostic model based on 20 disulfidptosis-related genes (DRGs) using LASSO Cox regression analyses. The robustness practicality were assessed via nomogram. Subsequent...

10.3389/fimmu.2024.1344637 article EN cc-by Frontiers in Immunology 2024-06-19

To investigate the contribution of de novo variants to Tourette disorder (TD) probands in China. Whole-exome sequencing (WES) conducted on 15 child-parent trios (45 samples) detected 25 coding variants, including 2 Likely Gene Disrupting (LGD) and 6 Missense3 variants. The LGD were consistently associated with TD risk (Fisher's exact test OR 2.69; p = 0.1952), although statistical significance was not achieved due small sample size. We then assessed relationship between genetic events...

10.1089/dna.2019.4746 article EN DNA and Cell Biology 2019-12-19

To assess the synergistic effects of gene polymorphisms renin-angiotensin-aldosterone system (RAAS) on essential hypertension (EH) in Kazakhs Xinjiang.A cross-sectional case-control association study was conducted 52 1 hypertensive and 623 normotensive subjects Kazakh ethnicity eight common single nucleotide (SNPs) interspersed over five genes RAAS. SNPs were genotyped by polymerase chain reaction-restriction fragment length polymorphism. Interactions among analyzed multifactor...

10.3109/10641963.2015.1060985 article EN Clinical and Experimental Hypertension 2015-08-13

The aim of the present study was to investigate whether measurement cytokines from abdominal exudate is valuable for early diagnosis prolonged postoperative ileus (PPOI) following colorectal surgery. In study, 100 consecutive patients who were scheduled undergo elective resection carcinoma sigmoid or rectum investigated. Abdominal obtained via a drain tube surgery detection interleukin (IL)-1β, IL-6 and tumour necrosis factor (TNF)-α. correlation among cytokine levels on days 1, 3 5...

10.3892/ol.2013.1465 article EN Oncology Letters 2013-07-15

Background Prolonged postoperative ileus (PPOI) is a common problem after major abdominal surgery and can cause morbidity, extended hospitalization, as well increased health care costs. Aim To investigate whether the levels of cytokines from exudate are predictive for early diagnosis PPOI colorectal surgery. Methods One hundred patients who had undergone elective resection carcinoma sigmoid or rectum were recruited. The was obtained drain tube to examine C-reactive protein (CRP),...

10.5301/jbm.5000028 article EN The International Journal of Biological Markers 2013-04-01

Abstract Background Studies have reported the impact of chronic childhood and adolescent tic disorder (TD) on families. However, few researches focused relationship between family environment diagnosis TD. We aim to assess influence couple structure onset Methods A total 660 parents patients with TD (aged 6–12 years) 641 controls completed questionnaires. Couple were selected by regression binary logistic analysis as risk factors. was divided into harmonious, common, hostile, divorced....

10.1002/mgg3.1286 article EN cc-by-nc-nd Molecular Genetics & Genomic Medicine 2020-05-18

The objective of this study is to investigate the effects laparoscopic and open operation on serum peritoneal inflammatory mediators in patients with right colon carcinoma.A total 100 were randomly divided into group (n = 50) 50). age, sex, time, blood loss, post-operative Dukes stage, time first passage flatus hospital stay recorded. levels hypersensitive C reactive protein (hsCRP) tumour necrosis factor-α (TNF-α) abdominal exudate measured by ELISA at pre-operative 2 h 6 24 h.There was no...

10.4103/jmas.jmas_217_17 article EN cc-by-nc-sa Journal of Minimal Access Surgery 2018-02-19

In this study, we aimed to evaluate the feasibility and safety of undergoing restorative proctocolectomy through ileal pouch-anal anastomosis (RPC-IPAA) with hand-assisted laparoscopic (HALS) in patients ulcerative colitis (UC).We reviewed 40 consecutive who underwent RPC-IPAA HALS or open technique for treatment UC between 2010 2013. Moreover, intra-/post-operative outcomes were compared.We found median operative time was significantly longer group while blood loss less than surgery. group,...

10.4103/jmas.jmas_230_16 article EN cc-by-nc-sa Journal of Minimal Access Surgery 2017-01-01

Objective To explore the sociodemographic patterning of risk factors for cardiovascular disease (CVD) in three isolated-based subgroups Uyghur population Xinjiang, China. Design A cross-sectional study. Between 2005 and 2008, a non-probability sampling design method was used to select specific groups rural populations based on their potential socioeconomic status (ie, isolated, semi-isolated open-environment status). Setting Three communities (named Desert, Turpan Yuli Rob) Southern Xinjiang...

10.1136/bmjopen-2012-002279 article EN cc-by-nc BMJ Open 2013-01-01

Objectives To help understand the pathogenesis of coronary heart disease (CHD) by doing blood metabonomics comparison on CHD patients with phlegm-turbidity syndrome and without syndrome, healthy controls.

10.1080/10826076.2023.2216771 article EN Journal of Liquid Chromatography &amp Related Technologies 2023-03-16

Quantitative evaluation of tic disorders (TDs) is challenging as there are few objective indicators that can be used for the assessment treatment outcomes. 18F-Fluorodeoxyglucose (FDG) a radioactive tracer able to cross blood-brain barrier and detected by positron emission tomography/CT (PET/CT). In present study, it was hypothesized FDG PET/CT scan applied reflect severity symptoms in rat TD model, where signals brain striatum evaluate efficacy with traditional Chinese medicine (TCM). A...

10.3892/etm.2020.9483 article EN Experimental and Therapeutic Medicine 2020-11-19
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