A5030377129- Chronic Obstructive Pulmonary Disease (COPD) Research
- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Cancer, Hypoxia, and Metabolism
- Information and Cyber Security
- Cyberloafing and Workplace Behavior
- Neonatal Health and Biochemistry
- CO2 Reduction Techniques and Catalysts
- Impact of Technology on Adolescents
- Diabetes Treatment and Management
- Metallurgical Processes and Thermodynamics
- Respiratory Support and Mechanisms
- Cardiovascular Disease and Adiposity
- Heme Oxygenase-1 and Carbon Monoxide
- Circular RNAs in diseases
- Advanced Malware Detection Techniques
- Metabolomics and Mass Spectrometry Studies
- Phytochemicals and Antioxidant Activities
- Tryptophan and brain disorders
- Metabolism, Diabetes, and Cancer
- Cancer-related Molecular Pathways
- Genetic Associations and Epidemiology
- Adipokines, Inflammation, and Metabolic Diseases
- Death Anxiety and Social Exclusion
- Chemokine receptors and signaling
State Key Laboratory of Respiratory Disease
2020-2025
Guangzhou Medical University
2020-2025
First Affiliated Hospital of Guangzhou Medical University
2020-2025
Nanchang University
2022-2025
First Affiliated Hospital of Nanchang University
2024-2025
Harbin Medical University
2022-2025
Longgang Central Hospital
2024-2025
Wenzhou Medical University
2025
China Medical University
2022-2024
East China University of Technology
2022-2023
It is unclear whether patients with Global Initiative for Chronic Obstructive Lung Disease stage 1 (mild) chronic obstructive pulmonary disease (COPD) have a higher risk of all-cause mortality than participants normal spirometry results. We used the data from National Health and Nutrition Examination Survey (NHANES) III 2007-2012, which included aged 20-79 years, to investigate mild COPD (whole population subgroups) spirometry. Mild was defined as prebronchodilator forced expiratory volume...
Abstract Background The association between diurnal temperature range (DTR) and hospitalization for exacerbation of chronic respiratory diseases (CRD) was rarely reported. Objectives To examine the DTR daily hospital admissions CRD find out potential effect modifications on this association. Method Data obstructive pulmonary disease (COPD), asthma bronchiectasis meteorology measures from 2013 through 2017 were obtained 21 cities in South China. After controlling effects mean temperature,...
The relationship between long-term ozone (O₃) exposure and readmission for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) remains elusive. In this study, we collected individual-level information on AECOPD hospitalizations from a standardized electronic database in Guangzhou January 1, 2014, to December 31, 2015. We calculated the annual mean O₃ concentration prior dates index hospitalization using patients' residential addresses. Employing Cox proportional hazards...
Nurses are at high risk of psychological distress including stress, depression, and anxiety due to low personnel density work demand. Despite mounting evidence showing that role stress is a factor for nurses' distress, the mediating moderating mechanisms underlying this relationship less known. This study tests mediation effect burnout in association between whether moderated by social support.A sample 623 Chinese nurses were recruited from all hepatological surgery departments Hunan...
<title>Abstract</title> <bold>Background</bold> Osseointegration is considered a prerequisite for predicting implant success, and structure, biocompatibility, properties of the are important parts factors that influence osseointegration. The focus current research on how to increase strength osseointegration shorten time.<bold>Methods</bold> In this research, different porous scaffolds, including uniform, radial-gradient, axial-gradient porous,were designed fabricated. Their mechanical...
Pyroptosis is a novel kind of programmed cell death and Caspase-1 plays key roles in driving pyroptosis. The current study aims to elucidate the molecular mechanism affecting cardiomyocyte pyroptosis myocardial ischemia/reperfusion (I/R) injury, both vivo vitro. A murine model I/R injury was established then treated with lentivirus-mediated shRNA targeting evaluate effect on injury. Further, silenced cardiomyocytes following hypoxia-reoxygenation (H/R) detect function mitochondrial...
BACKGROUND We investigated the association between 8 single-nucleotide polymorphisms (SNPs) at 3 genetic loci (CDKAL1, CDKN2A/2B and FTO) with type 2 diabetes (T2D) in a Uyghur population. MATERIAL AND METHODS A case-control study of 879 patients T2D 895 non-diabetic controls was conducted Hospital Xinjiang Medical University 2010 2013. Eight SNPs CDKAL1, FTO were analyzed using Sequenom MassARRAY®SNP genotyping. Factors associated assessed by logistic regression analyses. Gene-gene...
To assess possible effect of air quality improvements, we investigated the temporal change in hospital admissions for acute exacerbations chronic obstructive pulmonary disease (AECOPD) associated with pollutant concentrations. We collected daily concentrations particulate matter (i.e., PM2.5, PM10 and PMcoarse), sulfur dioxide (SO2), nitrogen (NO2), carbon monoxide (CO), ozone (O3), AECOPD 21 cities Guangdong from 2013 to 2017. examined association pollution using two-stage time-series...
The previous findings on the correlation between spirometry and high-density lipoprotein (HDL) cholesterol are intriguing yet conflicting. aim of this research is to evaluate relationship HDL levels as well imaging parameters in patients with chronic obstructive pulmonary disease (COPD) China.
Cervical cancer remains one of the leading causes cancer-related deaths among women globally, and there is still a need to research molecular targets that can be used for prognosis assessment personalized therapies. Here, we investigate role potential target ribosomal L22-like 1 (RPL22L1) on cervical cancer, identify its mechanisms, explore related applications in Multiple cohorts online, tissue microarrays clinical specimens were analyzed association between RPL22L1 expression patient...
Osseointegration is considered a prerequisite for predicting implant success, and structure, biocompatibility, properties of the are important parts factors that influence osseointegration. The focus current research on how to increase strength osseointegration shorten time. In this research, different porous scaffolds, including uniform, radial-gradient, axial-gradient porous, were designed fabricated. Their mechanical biocompatibility comprehensively evaluated through tests in vitro...
Alterations in glycolysis play a crucial role cancer cells, influencing tumor aggressiveness and therapeutic effect, particularly pancreatic adenocarcinoma (PAAD). However, the specific glycolysis-related genes involved PAAD progression remain poorly understood. This study established molecular subtypes with distinct survival outcomes using TCGA datasets. The favorable prognosis subtype exhibited enhanced immune infiltration an activated microenvironment. A prognostic model effectively...
Purpose. To explore the regulatory effects of liraglutide on kidney and liver through miR-34a/SIRT1 pathway with related factors in diabetic nephropathy (DN) rats. Methods. DN rats were randomly divided into two groups ( <a:math xmlns:a="http://www.w3.org/1998/Math/MathML" id="M1"> <a:mi>n</a:mi> <a:mo>=</a:mo> <a:mn>10</a:mn> </a:math> ) injected or normal saline twice a day. The 24-hour urine microalbumin content biochemical index levels measured. qRT-PCR was performed to detect expression...