A5102766513- RNA modifications and cancer
- Cancer-related molecular mechanisms research
- Air Quality and Health Impacts
- Ferroptosis and cancer prognosis
- Per- and polyfluoroalkyl substances research
- Toxic Organic Pollutants Impact
- Health, Environment, Cognitive Aging
- Circular RNAs in diseases
- Effects and risks of endocrine disrupting chemicals
- Heavy Metal Exposure and Toxicity
- Liver Disease Diagnosis and Treatment
- MicroRNA in disease regulation
- Birth, Development, and Health
- Gestational Diabetes Research and Management
- DNA Repair Mechanisms
- Epigenetics and DNA Methylation
- Cancer, Hypoxia, and Metabolism
- Nutrition, Genetics, and Disease
- Cancer, Lipids, and Metabolism
- Hemoglobinopathies and Related Disorders
- Genetic factors in colorectal cancer
- Atmospheric chemistry and aerosols
- Nutritional Studies and Diet
- Cancer-related Molecular Pathways
- Hepatocellular Carcinoma Treatment and Prognosis
Guilin Medical University
2024-2025
Guangxi Medical University
2016-2025
Zhejiang University of Technology
2023-2024
Tumor Hospital of Guangxi Medical University
2017-2023
Hunan Provincial Maternal and Child Health Hospital
2023
National University of Singapore
2021
Xinjiang Medical University
2011-2018
Sun Yat-sen University
2013-2018
The Seventh Affiliated Hospital of Sun Yat-sen University
2018
First Affiliated Hospital of Xinjiang Medical University
2011-2018
Growing evidence has revealed the impacts of exposure to fine particulate matter (PM
Serological detection of Epstein-Barr virus (EBV) antibodies is frequently used in nasopharyngeal carcinoma (NPC) mass screening. However, the large number seropositive subjects who require close follow-up still a big burden. The present study aimed to detect EBV load high-risk population for against EBV, as well examine whether assay DNA might reduce and improve early NPC. A prospective population-based cohort was conducted southern China from 2006 through 2013. Among 22,186 participants,...
Preterm birth (PTB), a serious adverse outcome, is the leading cause of perinatal mortality and morbidity. Bisphenols induce endocrine disruption that spreads across placenta, which may affect fetal growth development. However, effects bisphenols on PTB, particularly their combined effects, remain unknown. This study investigated association between prenatal bisphenol exposure PTB. Study participants were 2023 mother-infant pairs selected from Guangxi Zhuang Birth Cohort. Maternal serum...
We investigated cross-sectional associations between children's neurodevelopment and their gut microbiota composition. Study children (36 months of age) lived in rural China (n = 46). Neurodevelopment was assessed using the Bayley Scales Infant Development, 2nd Edition, yielding Mental Developmental Index (MDI) Psychomotor (PDI). Children's 16S rRNA gene profiling. Microbial diversity characterized alpha patterns. Additionally, 3 coabundance factors were determined for 25 most abundant taxa....
Prenatal exposure to outdoor air pollution have been associated with birth outcomes. However, there is limited evidence on the adverse effects of household indoor worldwide, much less in rural areas China. This study aimed explore associations environmental factors (primary cooking fuel, housing renovation, and home ventilation) four outcomes (preterm (PTB), small for gestational age (SGA), low weight (LBW), term (T-LBW)). We conducted a cohort involving 10,324 pregnancies women who...
Telomere length (TL) is an important biomarker of biological aging and disease that may be affected by prenatal exposure to environmental pollutants. Birth seasons have been linked reproductive immune-related diseases. Prenatal per- polyfluoroalkyl substance (PFAS) has associated with adverse birth outcomes, but the effects PFAS on newborn TL are poorly understood.To explore individual combined maternal TL, exploration interaction between TL.Between June 2015 May 2018, a total 499...
Fetal sex hormone homeostasis disruption could lead to reproductive and developmental abnormalities. However, previous studies have reported inconsistent findings regarding the association of maternal per- polyfluoroalkyl substances (PFAS) exposure with fetal levels. A total 277 mother-infant pairs from Guangxi Zhuang Birth Cohort Study between 2015 2019 were selected. We quantified nine PFAS in serum early pregnancy, detected three hormones, namely, estradiol (E2), progesterone (P4)...
<h3>Objectives</h3> To explore the potential dose–response relationship between manganese (Mn) exposure and cognitive function also plasma brain-derived neurotrophic factor (BDNF) levels in occupational Mn workers. <h3>Methods</h3> A total 819 workers were identified from our Mn-exposed workers, 293 control recruited same region. All exposed divided into three groups based on cumulative index. The Montreal Cognitive Assessment (MoCA) test was applied to estimate for all subjects. Plasma BDNF...
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths. The average survival and 5-year rates HCC patients still remains poor. Thus, there an urgent need to better understand mechanisms cancer progression in identify useful biomarkers predict prognosis. Public data portals including Oncomine, Cancer Genome Atlas (TCGA) Gene Expression Omnibus (GEO) profiles were used retrieve HCC-related microarrays potential genes contributed progression. Bioinformatics analyses...
The forkhead box O (FOXO) transcription factors play important roles in various cancer development including Hepatocellular Carcinoma (HCC). In this study we conducted a hospital-based case control 1049 cases (HCC patients) and 1052 controls (non-tumor to examine whether single nucleotide polymorphisms (SNPs) within microRNA (miRNA) target sites of FOXO genes confer HCC susceptibility. A total three miRNA site SNPs the 3' untranslated regions (UTR) FOXO1 (rs17592236), FOXO3 (rs4946936) FOXO4...
BACKGROUND We investigated the association between 8 single-nucleotide polymorphisms (SNPs) at 3 genetic loci (CDKAL1, CDKN2A/2B and FTO) with type 2 diabetes (T2D) in a Uyghur population. MATERIAL AND METHODS A case-control study of 879 patients T2D 895 non-diabetic controls was conducted Hospital Xinjiang Medical University 2010 2013. Eight SNPs CDKAL1, FTO were analyzed using Sequenom MassARRAY®SNP genotyping. Factors associated assessed by logistic regression analyses. Gene-gene...