- Cardiovascular and exercise physiology
- Sports Performance and Training
- Heart Rate Variability and Autonomic Control
- Physical Activity and Health
- Adipose Tissue and Metabolism
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Cardiovascular Effects of Exercise
- Behavioral Health and Interventions
- Muscle metabolism and nutrition
- Diet and metabolism studies
- Muscle activation and electromyography studies
- Metabolomics and Mass Spectrometry Studies
- Spatial Cognition and Navigation
- Diabetes Management and Research
- Mental Health Research Topics
- Cardiovascular Function and Risk Factors
- Pediatric Pain Management Techniques
- Infant Development and Preterm Care
- Psychosomatic Disorders and Their Treatments
- Recommender Systems and Techniques
- High Altitude and Hypoxia
- Carbon Dioxide Capture Technologies
- Augmented Reality Applications
- Nursing Roles and Practices
University Children's Hospital Tübingen
2020-2025
University of Tübingen
2018-2023
University of Calgary
2016-2018
Western University
2016
Critical power (CP) conceptually represents the highest output (PO) at physiological steady-state. In cycling exercise, CP is traditionally derived from hyperbolic relationship of ∼5 time-to-exhaustion trials (TTE) (CPHYP). Recently, a 3-min all-out test (CP3MIN) has been proposed for estimation as well maximal lactate steady-state (MLSS). The aim this study was to compare POs CPHYP, CP3MIN, and MLSS, oxygen uptake blood concentrations MLSS. Thirteen healthy young subjects (age, 26 ± 3years;...
Abstract Purpose We investigated the cardiovascular individual response to 6 weeks (3×/week) of work-matched within severe-intensity domain (high-intensity interval training, HIIT) or moderate-intensity (moderate-intensity continuous MICT). In addition, we analyzed factors at baseline underlying variability. Methods 42 healthy sedentary participants were randomly assigned HIIT MICT. applied region practical equivalence-method for identifying levels responders maximal oxygen uptake (V̇O 2max...
The use of continuous glucose monitors (CGMs) in individuals living without diabetes is increasing. purpose this study was to profile various CGM metrics around nutritional intake, sleep and exercise a large cohort physically active men women any known metabolic disease diagnosis better understand the normative glycemic response these common stimuli. A total 12,504 adults (age 40 ± 11 years, BMI 23.8 3.6 kg/m2; 23% self-identified as women) wore real-time (Abbott Libre Sense Sport Glucose...
This study characterized central and peripheral adaptations to domain-specific endurance exercise training. Eighty-four young healthy participants were randomly assigned age- sex-matched groups of: continuous cycling in the 1) moderate (MOD)-, 2) lower heavy (HVY1)-, 3) upper heavy-intensity (HVY2)- domain; interval 4) severe-intensity domain (i.e., high-intensity training (HIIT), or 5) extreme-intensity sprint-interval (SIT)); 6) control (CON). Two 3-week phases of (three sessions per week)...
Background. Physical activity induces a range of physiological and molecular adaptations, particularly affecting skeletal muscle the cardiovascular system, regulating both tissue architecture metabolic pathways. Emerging evidence suggests that PIWI-interacting RNAs (piRNAs) may serve as potential biomarkers for these adaptations. Methods. This study selected eight participants iReAct (DRKS00017446) piRNA analysis. Baseline assessments included demographic profiling fitness evaluation,...
Physical activity is a substantial promoter for health and well-being. Yet, while an increasing number of studies shows that the responsiveness to physical highly individual, most focus this issue from only one perspective neglect other contributing aspects. In reference biopsychosocial framework, goal our study examine how physically inactive individuals respond two distinct standardized endurance trainings on various levels. Based assessment activity- health-related biographical...
The evaluation of the maximal oxygen uptake () following exercise training is classical assessment effectiveness. Research has lacked in investigating whether individuals that do not respond to intervention (), also improve other health-related parameters. We aimed investigate cardiovascular and metabolic adaptations (i.e., performance, body composition, blood pressure, vascular function, fasting markers, resting cardiac function morphology) among participants who showed different levels...
This study compared the responses of two priming exercises similar fatigue on adjustment oxygen uptake time constant (τV̇O2) in cycling. Ten healthy young adults (25 ± 3 yr) performed: three step transitions from a 20-W baseline to power output (PO) below gas exchange threshold (MOD, MODPRE); 3-min bout (P3MIN) at 90% peak PO (POpeak), followed by MOD (MOD3MIN); and 6-min (P6MIN) 80% POpeak, (MOD6MIN). The O2 supply-to-O2 demand ([HHb]/V̇O2) ratio was calculated for MODPRE, MOD3MIN, MOD6MIN....
Using a large database of continuous glucose monitoring (CGM) data, this study aimed to gain insights into the association between pre-exercise food ingestion timing and reactive hypoglycemia. A group 6,761 users self-reported 48,799 events logged minute-by-minute CGM, which was used detect hypoglycemia (<70 mg/dL) in first 30 min exercise. linear non-linear binomial logistic regression model investigate probability experiencing An analysis variance conducted compare predictive ability...
Affect experienced during an exercise session is supposed to predict future behavior. However, empirical evidence reveals high variability in affective response different modalities. Thus, the purpose of present study was compare acute and its variation three endurance modalities: (a) moderate-intensity continuous (MICE), (b) vigorous-intensity (VICE), (c) high-intensity interval (HIIE). Using dual-mode theory as a theoretical framework, cognitive interoceptive factors were considered...
microRNAs (miRs) have been proposed as a promising new class of biomarkers in the context training adaptation. Using microarray analysis, we studied skeletal muscle miR patterns sedentary young healthy females (n = 6) before and after single submaximal bout endurance exercise (‘reference training’). Subsequently, participants were subjected to structured program, consisting six weeks moderate-intensity continuous (MICT) high-intensity interval (HIIT) randomized order. In vastus lateralis...
In chronometric mental rotation tasks, sex differences are widely discussed. Most studies find men to be more skilled in than women, which can explained by the holistic strategy that they use rotate stimuli. Women believed apply a piecemeal strategy. So far, there have been no investigating this phenomenon using eye-tacking methods combination with electroencephalography (EEG) analysis: present study compared behavioral responses, EEG activity, and eye movements of 15 women while solving...
Small, non-coding RNAs (microRNAs) have been shown to regulate gene expression in response exercise various tissues and organs, thus possibly coordinating their adaptive response. Thus, it is likely that differential microRNA might be one of the factors are responsible for different training responses individuals. Consequently, determining patterns a promising approach toward development individualized strategies. However, little known on (1) regulation by regimens (2) possible correlations...
Regular exercise fosters fitness-enhancing benefits. We assume that interventions become successful and sustainable if physiological benefits of are also subjectively perceivable. The goal this study was to examine how young inactive adults physiologically respond an intervention those responses experienced . Furthermore, we aimed assess whether the sequence two distinct endurance-based modes has impact on physical fitness. Thirty-one were assessed for substudy larger iReAct study....
In exercise physiology, laboratory components help students connect theoretical concepts to their own experiences and introduce them data collection, analysis, interpretation using classic techniques. Most courses include a lab protocol that involves exhaustive incremental during which expired gas volumes concentrations of oxygen carbon dioxide are measured. During these protocols, there characteristic alterations in exchange ventilatory profiles give rise two thresholds: the threshold (GET)...