A5056793891- Animal Disease Management and Epidemiology
- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Vector-Borne Animal Diseases
- Microbial infections and disease research
- Animal Behavior and Welfare Studies
- Human-Animal Interaction Studies
- Zoonotic diseases and public health
- Viral Infections and Vectors
- Agricultural safety and regulations
- Viral gastroenteritis research and epidemiology
- Veterinary Practice and Education Studies
- COVID-19 epidemiological studies
- Genetic and phenotypic traits in livestock
- Milk Quality and Mastitis in Dairy Cows
- Agriculture and Farm Safety
- Diagnosis and treatment of tuberculosis
- Insect and Pesticide Research
- Infectious Diseases and Mycology
- Veterinary Equine Medical Research
- SARS-CoV-2 and COVID-19 Research
- Data-Driven Disease Surveillance
- T-cell and Retrovirus Studies
- Forensic Entomology and Diptera Studies
- Livestock and Poultry Management
Dr. V. M. Government Medical College
2024-2025
University College Dublin
2015-2024
UCD Centre for Veterinary Epidemiology and Risk Analysis
2011-2024
University of Zurich
2017-2023
London School of Hygiene & Tropical Medicine
2022
European Food Safety Authority
2021
Laboratoire de Neurosciences Cognitives
2021
Département Santé Animale
2003-2019
Animal Welfare Institute
2017-2019
European Commission
2019
The Scientific Committee (SC) reconfirms that the benchmark dose (BMD) approach is a scientifically more advanced method compared to NOAEL for deriving Reference Point (RP). Most of modifications made SC guidance 2009 concern section providing on how apply BMD approach. Model averaging recommended as preferred calculating confidence interval, while acknowledging respective tools are still under development and may not be easily accessible all. Therefore, selecting or rejecting models...
This Guidance document describes harmonised risk assessment methodologies for combined exposure to multiple chemicals all relevant areas within EFSA's remit, i.e. human health, animal health and ecological areas. First, a short review of the key terms, scientific basis approaches assessing (eco)toxicology is given, including existing frameworks these assessments. background was evaluated, resulting in framework chemicals. The based on steps (problem formulation, assessment, hazard...
Objectives Our objective was to review the literature on inferred duration of infectious period COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus, and provide an overview variation depending methodological approach. Design Rapid scoping review. Literature with fixed search terms, up 1 April 2020. Central tendency parameter estimates for in (A) asymptomatic (B) symptomatic cases from (1) virological studies (repeated testing), (2) tracing (3) modelling...
EFSA requested the Scientific Committee to develop a guidance document on use of weight evidence approach in scientific assessments for all areas under EFSA's remit.The addresses approaches using both qualitative and quantitative approaches.Several case studies covering various remit are annexed illustrate applicability proposed approach.Weight assessment is defined this as process which integrated determine relative support possible answers question.This considers comprising three basic...
Uncertainty analysis is the process of identifying limitations in scientific knowledge and evaluating their implications for conclusions.It therefore relevant all EFSA's assessments also necessary, to ensure that assessment conclusions provide reliable information decisionmaking.The form extent uncertainty analysis, how should be reported, vary widely depending on nature context each degree present.This document provides concise guidance identify which options are appropriate assessment,...
The European Food Safety Authority has produced this Guidance on human and animal health aspects (Part 1) of the risk assessment nanoscience nanotechnology applications in food feed chain. It covers application areas within EFSA's remit, e.g. novel foods, contact materials, food/feed additives pesticides. takes account new developments that have taken place since publication previous 2011. Potential future are suggested scientific literature for nanoencapsulated delivery systems...
Q fever is a disease of humans, caused by Coxiella burnetii, and large range animals can be infected. This paper presents review the epidemiology in humans farm between 1982 2010, using case studies from four European countries (Bulgaria, France, Germany Netherlands). The Netherlands had outbreak 2007 other history research. Within all countries, serological prevalence C. burnetii infection reported incidence varies broadly both humans. Proximity to contact with infected or their birth...
EFSA and EMA have jointly reviewed measures taken in the EU to reduce need for use of antimicrobials food-producing animals, resultant impacts on antimicrobial resistance (AMR). Reduction strategies been implemented successfully some Member States. Such include national reduction targets, benchmarking use, controls prescribing restrictions specific critically important antimicrobials, together with improvements animal husbandry disease prevention control measures. Due multiplicity factors...
The Scientific Committee confirms that the Threshold of Toxicological Concern (TTC) is a pragmatic screening and prioritisation tool for use in food safety assessment. This Guidance provides clear step-by-step instructions TTC approach. inclusion exclusion criteria are defined decision tree explained. approach can be used when chemical structure substance known, there limited chemical-specific toxicity data exposure estimated. should not substances which EU food/feed legislation requires...
The EFSA has updated the Guidance on risk assessment of application nanoscience and nanotechnologies in food feed chain, human animal health. It covers areas within EFSA's remit, including novel foods, contact materials, food/feed additives pesticides. guidance, now Scientific Committee nano (SC Nano-RA), taken account relevant scientific studies that provide insights to physico-chemical properties, exposure hazard characterisation nanomaterials applicability. Together with accompanying...
To meet the general requirement for transparency in EFSA's work, all its scientific assessments must consider uncertainty. Assessments say clearly and unambiguously what sources of uncertainty have been identified is their impact on assessment conclusion. This applies to areas, types affecting assessment. current Opinion describes principles methods supporting a concise Guidance Document Uncertainty Scientific Assessment, published separately. These documents do not prescribe specific...
Following a request from the European Commission to EFSA, EFSA Scientific Committee (SC) prepared guidance for risk assessment of substances present in food intended infants below 16 weeks age.In its approach develop this guidance, SC took into account, among others, (i) an exposure based on infant formula as only source nutrition; (ii) knowledge organ development human infants, including gut, metabolic and excretory capacities, brain barriers, immune system, endocrine reproductive systems;...
Following a mandate from the European Commission, EFSA has developed Guidance on Technical Requirements (Guidance Particle-TR), defining criteria for assessing presence of fraction small particles, and setting out information requirements applications in regulated food feed product areas (e.g. novel food, food/feed additives, contact materials pesticides). These apply to particles requiring specific assessment at nanoscale conventional that do not meet definition engineered nanomaterial as...
This update on the African swine fever (ASF) outbreaks in EU demonstrated that out of all tested wild boar found dead, proportion positive samples peaked winter and summer. For domestic pigs only, a summer peak was evident. Despite existence several plausible factors could result observed seasonality, there is no evidence to prove causality. Wild density most influential risk factor for occurrence ASF boar. In vast majority introductions pig holdings, direct contact with infected or excluded...
The EFSA Scientific Committee addressed in this document the peculiarities related to genotoxicity assessment of chemical mixtures. suggests that first a mixture should be chemically characterised as far possible. Although characterisation mixtures is relevant also for other toxicity aspects, it particularly significant genotoxicity. If contains one or more substances are individually assessed genotoxic
The Scientific Committee (SC) reconfirms that the benchmark dose (BMD) approach is a scientifically more advanced method compared to no-observed-adverse-effect-level (NOAEL) for deriving Reference Point (RP). major change previous Guidance (EFSA SC, 2017) concerns Section 2.5, in which from frequentist Bayesian paradigm recommended. In former, uncertainty about unknown parameters measured by confidence and significance levels, interpreted calibrated under hypothetical repetition, while...
Copper is an essential micronutrient and also a regulated product used in organic conventional farming pest management. Both deficiency excessive exposure to copper can have adverse health effects. In this Scientific Opinion, the EFSA 2021 harmonised approach for establishing health-based guidance values (HBGVs) substances that are products nutrients was resolve divergent existing HBGVs copper. The tightly homeostasis prevents toxicity manifestation short term, but development of chronic...
Calfhood diseases have a major impact on the economic viability of cattle operations. This is first in three part review series calf health from birth to weaning, focusing preventive measures. The considers both pre- and periparturient management factors influencing health, colostrum beef dairy calves further nutrition weaning calves.
There have been considerable recent advancements in animal breeding and genetics relevant to disease control cattle, which can now be utilised as part of an overall programme for improved cattle health. This review summarises the contribution genetic makeup differences resistance many diseases affecting cattle. Significant variation susceptibility does exist among suggesting that selection will fruitful. Deficiencies accurately recorded data on individual are, however, currently hindering...
Calfhood diseases have a major impact on the economic viability of cattle operations. The second this three part review series considers management diarrhoeic in pre-weaned calves. In neonatal calf diarrhoea, oral rehydration therapy is single most important therapeutic measure to be carried out by farmer and usually successful if instigated immediately after diarrhoea has developed. Continued feeding milk or replacer calves important, prevent malnourishment weight loss affected...